Skip to main content
Erschienen in: European Journal of Medical Research 7/2011

01.12.2011 | Research

Histopathological examination of newly-developed adhesive silicone denture relining material

verfasst von: M. Tomida, K. Nakano, M. Sato, S. Matsuura, T. Kawakami

Erschienen in: European Journal of Medical Research | Ausgabe 7/2011

Einloggen, um Zugang zu erhalten

Abstract

We aimed to evaluate the subcutaneous tissue reaction to a newly developed adhesive silicone denture relining material, SG, (Neo Dental Chemical Products Co., Ltd. Tokyo, Japan). We embedded the experimental material SG and another existing control material, Roeko Seal (RS), in the dorsal area of 22 male ddY mice. One week and 12 weeks after the embedding, the tissues surrounding the embedded materials were removed and a histopathological examination was performed. The results demonstrate that the basic histopathological aspects are the formation of granulation tissue and the change of the tissue to fibrous capsule over time. The results suggests that the newly-developed SG is safe as compared with the control RS, whose composition is similar.
Literatur
1.
Zurück zum Zitat Kawakami T, Nakamura C, Eda S: Fate of 14 C-labelled dimethylpolysiloxane (silicone oil) in a root canal filling material embedded in rat subcutaneous tissues. Dent Mater 1987, 3: 256–260. 10.1016/S0109-5641(87)80083-0CrossRefPubMed Kawakami T, Nakamura C, Eda S: Fate of 14 C-labelled dimethylpolysiloxane (silicone oil) in a root canal filling material embedded in rat subcutaneous tissues. Dent Mater 1987, 3: 256–260. 10.1016/S0109-5641(87)80083-0CrossRefPubMed
2.
Zurück zum Zitat Kawakami T, Eda S: Excretion of silicone oil embedded in rat subcutaneous tissue. Med Sci Res 1988, 16: 837. Kawakami T, Eda S: Excretion of silicone oil embedded in rat subcutaneous tissue. Med Sci Res 1988, 16: 837.
3.
Zurück zum Zitat Kawakami T, Nakamura C, Uji H, Hasegawa H, Eda S: Fate of the silicone oil component of a root canal filling material embedded in rat subcutaneous tissue. J Matsumoto Dent Univ Soc (Matsumoto Shigaku) 1989, 15: 167–172. Kawakami T, Nakamura C, Uji H, Hasegawa H, Eda S: Fate of the silicone oil component of a root canal filling material embedded in rat subcutaneous tissue. J Matsumoto Dent Univ Soc (Matsumoto Shigaku) 1989, 15: 167–172.
4.
Zurück zum Zitat Kawakami T, Yoshikawa M, Eda S: Tissue reactions to dimethylpolysiloxane embedded subcutaneously in rats. Med Sci Res 1990, 18: 485–487. Kawakami T, Yoshikawa M, Eda S: Tissue reactions to dimethylpolysiloxane embedded subcutaneously in rats. Med Sci Res 1990, 18: 485–487.
5.
Zurück zum Zitat Silva-Herzog D, Ramirez T, Mora J, Pozos AJ, Silva LA, Silva RA, Nelson-Filho P: Preliminary study of inflammatory response to subcutaneous implantation of three root canal sealers. Int Endod J 2011. doi: 10.111/j.1365–2591.2010.01849.x. Silva-Herzog D, Ramirez T, Mora J, Pozos AJ, Silva LA, Silva RA, Nelson-Filho P: Preliminary study of inflammatory response to subcutaneous implantation of three root canal sealers. Int Endod J 2011. doi: 10.111/j.1365–2591.2010.01849.x.
6.
Zurück zum Zitat Tanomaru JMG, Cezare L, Goncalves M, Filho MT: Evaluation of the radiopacity of root canal sealers by digitization of radiographic images. J Appl Oral Sci 2004, 12: 355–357. 10.1590/S1678-77572004000400019CrossRefPubMed Tanomaru JMG, Cezare L, Goncalves M, Filho MT: Evaluation of the radiopacity of root canal sealers by digitization of radiographic images. J Appl Oral Sci 2004, 12: 355–357. 10.1590/S1678-77572004000400019CrossRefPubMed
7.
Zurück zum Zitat Tanomaru-Filho M, Tanomaru JMG, Leonardo MR, da Silva LAB: Periapical repair after root canal filling with different root canal sealers. Braz Dent J 2009, 20: 389–395.CrossRefPubMed Tanomaru-Filho M, Tanomaru JMG, Leonardo MR, da Silva LAB: Periapical repair after root canal filling with different root canal sealers. Braz Dent J 2009, 20: 389–395.CrossRefPubMed
8.
Zurück zum Zitat Lucena-Martin C, Ferrer-Luque CM, Gonzalez-Rodriquez MP, Robles-Gijon V, de Mondelo JMN-R: A comparative study of apical leakage of Endomethasone, Top Seal, and Roeko Seal sealer cements. J Endod 2002, 28: 423–426. 10.1097/00004770-200206000-00001CrossRefPubMed Lucena-Martin C, Ferrer-Luque CM, Gonzalez-Rodriquez MP, Robles-Gijon V, de Mondelo JMN-R: A comparative study of apical leakage of Endomethasone, Top Seal, and Roeko Seal sealer cements. J Endod 2002, 28: 423–426. 10.1097/00004770-200206000-00001CrossRefPubMed
9.
Zurück zum Zitat Barbizam JVB, Souza M, Cecchin D, Dabbel J: Effectiveness of a silicon-based root canal sealer for filling of simulated lateral canals. Braz Dent J 2007, 18: 20–23.CrossRefPubMed Barbizam JVB, Souza M, Cecchin D, Dabbel J: Effectiveness of a silicon-based root canal sealer for filling of simulated lateral canals. Braz Dent J 2007, 18: 20–23.CrossRefPubMed
10.
Zurück zum Zitat Upman PJ: ISO 1099,3–6: Test for local effects after implantation. BONEZone 2006,5(1):50–52. Upman PJ: ISO 1099,3–6: Test for local effects after implantation. BONEZone 2006,5(1):50–52.
11.
Zurück zum Zitat International Organization for Standardization (ISO): Biological Evaluation of Medical Devices-Part 1: Evaluation and testing, ISO 10993–1:2003 (E). Geneva, Switzerland. 2003. International Organization for Standardization (ISO): Biological Evaluation of Medical Devices-Part 1: Evaluation and testing, ISO 10993–1:2003 (E). Geneva, Switzerland. 2003.
Metadaten
Titel
Histopathological examination of newly-developed adhesive silicone denture relining material
verfasst von
M. Tomida
K. Nakano
M. Sato
S. Matsuura
T. Kawakami
Publikationsdatum
01.12.2011
Verlag
BioMed Central
Erschienen in
European Journal of Medical Research / Ausgabe 7/2011
Elektronische ISSN: 2047-783X
DOI
https://doi.org/10.1186/2047-783X-16-7-328

Weitere Artikel der Ausgabe 7/2011

European Journal of Medical Research 7/2011 Zur Ausgabe