Skip to main content
main-content

04.05.2018 | Local-Regional Evaluation and Therapy (DM Euhus, Section Editor) | Ausgabe 2/2018

Current Breast Cancer Reports 2/2018

Individualizing Local-Regional Therapy of Breast Cancer in the Elderly

Zeitschrift:
Current Breast Cancer Reports > Ausgabe 2/2018
Autoren:
Apoorve Nayyar, Trevor A. Jolly, Ellen T. Jones, Kandace P. McGuire, Hyman B. Muss, Kristalyn K. Gallagher
Wichtige Hinweise
This article is part of the Topical Collection on Local-Regional Evaluation and Therapy

Abstract

Purpose of Review

The treatment of breast cancer in the elderly population requires a tailored approach. We summarize the current best evidence for personalized local-regional therapy in breast cancer patients older than 70.

Recent Findings

Breast cancer treatment in older adults incorporates the use of geriatric assessment tools to best evaluate functional status and treatment tolerability while accounting for the biologic profile of the disease. Surgical resection of the primary tumor with lymph node evaluation remains the cornerstone of local-regional control. Recent clinical trials demonstrate that surgery and radiation therapy may, however, be safely omitted in selected patients who are eligible for primary endocrine therapy. In patients with high-risk node-positive disease, DFS can be improved by systemic chemotherapy, but potential toxicity should be carefully considered in this population.

Summary

Patient-specific evaluation of the risks of both under- and over-treatment of breast cancer in the older adult is essential for delivering optimal care in this population.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Weitere Produktempfehlungen anzeigen
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 2/2018

Current Breast Cancer Reports 2/2018Zur Ausgabe

Local-Regional Evaluation and Therapy (DM Euhus, Section Editor)

Choosing Wisely: Optimizing Routine Workup for the Newly Diagnosed Breast Cancer Patient

Local-Regional Evaluation and Therapy (DM Euhus, Section Editor)

Managing Patient with Mutations in PALB2, CHEK2, or ATM

Local-Regional Evaluation and Therapy (DM Euhus, Section Editor)

Estimating Contralateral Breast Cancer Risk

Local-Regional Evaluation and Therapy (DM Euhus, Section Editor)

Prepectoral Breast Reconstruction

Local-Regional Evaluation and Therapy (DM Euhus, Section Editor)

Breast Density and the Importance of Supplemental Screening

Translational Research (RL Aft, Section Editor)

HER2 Activating Mutations in Estrogen Receptor Positive Breast Cancer

  1. Das kostenlose Testabonnement läuft nach 14 Tagen automatisch und formlos aus. Dieses Abonnement kann nur einmal getestet werden.

Neu im Fachgebiet Onkologie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Onkologie und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise