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04.05.2018 | Local-Regional Evaluation and Therapy (DM Euhus, Section Editor)

Individualizing Local-Regional Therapy of Breast Cancer in the Elderly

verfasst von: Apoorve Nayyar, Trevor A. Jolly, Ellen T. Jones, Kandace P. McGuire, Hyman B. Muss, Kristalyn K. Gallagher

Erschienen in: Current Breast Cancer Reports | Ausgabe 2/2018

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Abstract

Purpose of Review

The treatment of breast cancer in the elderly population requires a tailored approach. We summarize the current best evidence for personalized local-regional therapy in breast cancer patients older than 70.

Recent Findings

Breast cancer treatment in older adults incorporates the use of geriatric assessment tools to best evaluate functional status and treatment tolerability while accounting for the biologic profile of the disease. Surgical resection of the primary tumor with lymph node evaluation remains the cornerstone of local-regional control. Recent clinical trials demonstrate that surgery and radiation therapy may, however, be safely omitted in selected patients who are eligible for primary endocrine therapy. In patients with high-risk node-positive disease, DFS can be improved by systemic chemotherapy, but potential toxicity should be carefully considered in this population.

Summary

Patient-specific evaluation of the risks of both under- and over-treatment of breast cancer in the older adult is essential for delivering optimal care in this population.

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Titel: Individualizing Local-Regional Therapy of Breast Cancer in the Elderly
verfasst von: Apoorve Nayyar
Trevor A. Jolly
Ellen T. Jones
Kandace P. McGuire
Hyman B. Muss
Kristalyn K. Gallagher
Publikationsdatum: 04.05.2018
Verlag: Springer US
Erschienen in: Current Breast Cancer Reports / Ausgabe 2/2018
Print ISSN: 1943-4588
Elektronische ISSN: 1943-4596
DOI: https://doi.org/10.1007/s12609-018-0272-0

Neu im Fachgebiet Onkologie

25.04.2024 | Nierenkarzinom | Nachrichten

Springer Medizin

Individualizing Local-Regional Therapy of Breast Cancer in the Elderly

Abstract

Purpose of Review

Recent Findings

Summary

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Adjuvante Immuntherapie verlängert Leben bei RCC

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

Bei Senioren mit Prostatakarzinom auf Anämie achten!

ICI-Therapie in der Schwangerschaft wird gut toleriert

Update Onkologie

Springer Medizin

Abstract

Purpose of Review

Recent Findings

Summary

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Neu im Fachgebiet Onkologie

Adjuvante Immuntherapie verlängert Leben bei RCC

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ICI-Therapie in der Schwangerschaft wird gut toleriert

Update Onkologie