Erschienen in:
01.07.2002 | Leading Article
Issues in the Conduct of Therapeutic Trials in Palliative Care
An Australian Perspective
verfasst von:
Dr Ian Maddocks
Erschienen in:
Drugs & Aging
|
Ausgabe 7/2002
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Abstract
Palliative care has been slow to demonstrate that its common interventions are supported by high levels of evidence. There are multiple reasons for this — historical and cultural, as well as the recognised difficulties of conducting studies in dying persons. There are problems in isolating the effect of a single intervention from the many other changing dimensions which attend the progress of terminal illness, and problems also in defining particular outcomes free from the contaminating effect of other simultaneous changes in a patient’s situation. Sickness is an interaction between disease and patient, and science sits more comfortably with the study of disease than with the understanding of the patient. Nevertheless, the therapies commonly employed for symptom management in individuals with advanced and terminal illness deserve more rigorous investigation to establish their efficacy. In Australia, new levels of government support for research have stimulated a closer examination of principles and practical guidelines for the conduct of research in this area of healthcare.