Approximately 38.4 million people live with human immunodeficiency virus (HIV) worldwide (UNAIDS, 2021). While advances in combination-antiretroviral therapy (cART) have reduced HIV progression, secondary effects of long-term infection arise …
verfasst von:
Samantha M. Ayoub, Breanna M. Holloway, Alannah H. Miranda, Benjamin Z. Roberts, Jared W. Young, Arpi Minassian, Ronald J. Ellis
The HIV pandemic remains a global public health challenge [ 1 ]. Despite significant progress in prevention and treatment, the UNAIDS 95–95-95 goals remain unmet [ 1 , 2 ]. To achieve these global targets by 2030, innovation is needed to improve …
verfasst von:
Shannon Bosman, Shriya Misra, Lili Marie Flax-Nel, Alastair van Heerden, Hilton Humphries, Zaynab Essack
Successful scale-up of HIV antiretroviral therapy (ART) has required simplifying access criteria and diversifying delivery channels to meet client needs and reduce strain on healthcare systems; a similar approach will likely be needed to scale up …
verfasst von:
Stephanie D. Roche, Daniel Were, Natalie D. Crawford, Angela Tembo, Jillian Pintye, Elizabeth Bukusi, Kenneth Ngure, Katrina F. Ortblad
As articulated in the U.S. Ending the HIV Epidemic (EHE) Plan, for the past decade, we have had the biomedical tools to effectively eliminate HIV transmission—highly sensitive tests to diagnose HIV infection, interventions to prevent and treat …
verfasst von:
Dennis H. Li, Kathryn Macapagal, Melissa Mongrella, Rana Saber, Brian Mustanski
The synthetic control method (SCM) was first described by Abadie and Gardeazabal in 2003 and expanded on by Abadie, Diamond, and Hainmueller in 2010. It is a design-based approach to causal inference related to difference-in-difference (DiD) …
verfasst von:
Sara Wallach, Suzue Saito, Harriet Nuwagaba-Biribonwoha, Lenhle Dube, Matthew R. Lamb
10.12.2019 | Complications of HIV and Antiretroviral Therapy (GA McComsey, Section Editor)
The recent and rapid demographic changes affecting people living with HIV (PLWH) produced a subset of older adults demanding a prompt response both in clinical practice and research setting.
verfasst von:
Giovanni Guaraldi, Jovana Milic, Cristina Mussini
27.11.2019 | Implementation Science (E Geng, Section Editor)
Despite growing optimism towards achieving 95–95–95 targets, the HIV epidemic in adolescents and young people aged 10–24 years remains one of the most persistent global public health challenges today. Adolescents and young people living with HIV …
verfasst von:
Daniella Mark, Susan Hrapcak, Wole Ameyan, Ronnie Lovich, Agnes Ronan, Kathrin Schmitz, Luann Hatane
19.10.2019 | Complications of HIV and Antiretroviral Therapy (GA McComsey, Section Editor)
Few can argue the dramatic impact that antiretroviral therapy (ART) given to pregnant women and their infants has had on the prevention of maternal to child transmission (PMTCT) of HIV. It is arguably one of the best achievements to date toward …
verfasst von:
Allison Ross Eckard, Stephanie E. Kirk, Nancy L. Hagood
