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Pain and Therapy OnlineFirst articles

Open Access 25.04.2024 | REVIEW

Clinical Assessment of Osteoarthritis Pain: Contemporary Scenario, Challenges, and Future Perspectives

The multifaceted nature of osteoarthritis (OA) pain presents a challenge in understanding and managing the condition. The diverse pain experiences, progression rates, individual responses to treatments, and complex disease mechanisms contribute to …

verfasst von:
Vidhu Sethi, Chetan Anand, Oscar Della Pasqua

Open Access 25.04.2024 | CASE SERIES

Ganglionic Local Opioid Analgesia at the Superior Cervical Ganglion: MRI-Verified Solution Spread

The injection of low-dose opioids (mainly buprenorphine or sufentanil) to different sympathetic ganglia has been termed “ganglionic local opioid analgesia” (GLOA) [ 1 , 2 ]. This form of therapy has been successfully used for numerous, often …

verfasst von:
Stefan Neuwersch-Sommeregger, Markus Köstenberger, Andreas Sandner-Kiesling, Matthias Fürstner, Isabel Igerc, Brigitte Trummer, Jessica Wuntschek, Wolfgang Pipam, Haro Stettner, Rudolf Likar, Georg Feigl

Open Access 16.04.2024 | ORIGINAL RESEARCH

Acute Treatment Patterns, Migraine Burden, and Healthcare Resource Use in People With Migraine: Results From the OVERCOME (EU) Observational Study

Migraine is a debilitating neurological condition with an overall prevalence of approximately 15% in Europe [ 1 ], and 1-year prevalences of 12.6% in Spain [ 2 ] and 16.6% in Germany [ 3 ]. Reported prevalence estimates vary between studies …

verfasst von:
Stefan Evers, Grazia Dell’Agnello, Diego Novick, H. Saygin Gonderten, Tommaso Panni, Julio Pascual

Open Access 09.04.2024 | ORIGINAL RESEARCH

Comparison of Thoracoscopy-Guided Thoracic Paravertebral Block and Ultrasound-Guided Thoracic Paravertebral Block in Postoperative Analgesia of Thoracoscopic Lung Cancer Radical Surgery: A Randomized Controlled Trial

Compared with traditional open thoracotomy, thoracoscopic minimally invasive surgery has many advantages. It requires a small incision, causes minimal trauma and less pain, and allows faster recovery [ 1 ]. Therefore, thoracoscopic minimally …

verfasst von:
Xia Xu, Ying-xin Xie, Meng Zhang, Jian-hui Du, Jin-xian He, Li-hong Hu

Open Access 28.03.2024 | ORIGINAL RESEARCH

Observational Retrospective Study in Patients Treated with Galcanezumab as Preventive Treatment for Migraine: The ORYGAM Study

Migraine is a neurologic disease described by the International Classification of Headache Disorders (ICHD-II) as a recurrent headache disorder manifesting in attacks lasting 4–72 h without treatment and with typical characteristics, such as …

verfasst von:
Samuel Díaz Insa, Ángel Guerrero, Javier Viguera, Vicente Medrano Martínez, Carlos Calle de Miguel, Jesús Porta-Etessam, Antonio Ciudad, Silvia Diaz-Cerezo, Ana Roncero Martín, Mercedes Núñez

Open Access 23.03.2024 | REVIEW

Pacific Spine and Pain Society (PSPS) Evidence Review of Surgical Treatments for Lumbar Degenerative Spinal Disease: A Narrative Review

Degenerative disorders of the spine have many etiologies, including hypertrophied ligamentum flavum, facet joint hypertrophy, degenerative disc disease, and osteophyte formation. This cascade of degenerative changes is largely the result of aging …

verfasst von:
Michael J. Dorsi, Patrick Buchanan, Chau Vu, Harjot S. Bhandal, David W. Lee, Samir Sheth, Phil M. Shumsky, Nolan J. Brown, Alexander Himstead, Ryan Mattie, Steven M. Falowski, Ramana Naidu, Jason E. Pope

Open Access 15.03.2024 | ORIGINAL RESEARCH

Analyzing the Effect of Intraoperative Stimulation Voltage on Facial Numbness Following Radiofrequency Thermocoagulation in the Treatment of Idiopathic Trigeminal Neuralgia

Idiopathic trigeminal neuralgia (ITN), also known as tic douloureux, is a condition characterized by severe facial pain without a clear cause, although it potentially involves vascular compression of the fifth cranial nerve [ 1 , 2 ]. This painful …

verfasst von:
Aitao Wang, Jingjing Bian, Na Li, Jiaxiang Ni, Lea Zila, Yuanzhang Tang

Open Access 13.03.2024 | ORIGINAL RESEARCH

Effects of Different Volumes of Ropivacaine for Pericapsular Nerve Group Block on Incidence of Quadriceps Weakness and Analgesic Efficacy Following Hip Arthroplasty: A Randomized Controlled Trial

Excitation of the sympathetic nervous system following hip fracture surgery can result from severe pain, contributing to the release of stress hormones into systemic circulation whereupon they can alter hemodynamic parameters, increase the …

verfasst von:
Huaichang Wen, Weihua Zhang, Yi Wang, Meijing Lu

Open Access 12.03.2024 | ORIGINAL RESEARCH

Real-world Impact of Fremanezumab on Migraine-Related Health Care Resource Utilization in Patients with Comorbidities, Acute Medication Overuse, and/or Unsatisfactory Prior Migraine Preventive Response

This article is published with digital features, including graphical abstract, to facilitate understanding of the article. To view digital features for this article, go to https://doi.org/10.6084/m9.figshare.25133801 .

verfasst von:
Dawn C. Buse, Lynda J. Krasenbaum, Michael J. Seminerio, Elizabeth R. Packnett, Karen Carr, Mario Ortega, Maurice T. Driessen

Open Access 06.03.2024 | REVIEW

The Role of the Combination Paracetamol/Caffeine in Treatment of Acute Migraine Pain: A Narrative Review

Headache is a widespread neurological disorder. Stovner et al.’s review [ 1 ] of literature data from all prevalence studies up to 2020 investigating the past-year prevalence of active headache disorders in the general adult population (i.e., how …

verfasst von:
Barbanti Piero, Allais Gianni, Cevoli Sabina, Guerzoni Simona, Valeriani Massimiliano, Vernieri Fabrizio

Open Access 02.03.2024 | REVIEW

Incorporation of “Artificial Intelligence” for Objective Pain Assessment: A Comprehensive Review

Pain is a significant health issue, and pain assessment is essential for proper diagnosis, follow-up, and effective management of pain. The conventional methods of pain assessment often suffer from subjectivity and variability. The main issue is …

verfasst von:
Salah N. El-Tallawy, Joseph V. Pergolizzi, Ingrid Vasiliu-Feltes, Rania S. Ahmed, JoAnn K. LeQuang, Hamdy N. El-Tallawy, Giustino Varrassi, Mohamed S. Nagiub

Open Access 01.02.2024 | ORIGINAL RESEARCH

Classical TAP vs. I TAP Using the Same Dose of Local Anesthetic in Elective Cesarean Section: A Randomized Controlled Trial

The most frequent surgical operation performed globally is a Cesarean section [ 1 ]. After a Cesarean section, there are primarily two types of pain: somatic pain from the abdominal wall and skin incisions and visceral pain coming from the uterus [ …2

verfasst von:
Wessam Zakaria El-Amrawy, Ahmed Mohamed El-Attar