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Erschienen in: International Urogynecology Journal 4/2006

01.08.2006 | Controversies in Urogynecology

The need for randomised controlled trials in urogynaecology

verfasst von: Christopher Maher, Bernhard Schuessler

Erschienen in: International Urogynecology Journal | Ausgabe 4/2006

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Excerpt

Research in urogynaecology is aimed at acquiring knowledge to improve the outcomes of the women that we treat. Confucius in 479 b.c. stated that the essence of knowledge is, having it, to apply it. Since that time, clinicians and researchers alike have searched for the truth. As early as 1747, James Lind performed a planned trial on scurvy:
I took 12 patients in the scurvy on board the Salisbury at sea. The cases were as similar as I could have them.... They lay together and had one diet common to them all. Two of these were ordered a quart of cider per day... two others took two spoonfuls of vinegar... Two were put on a course of sea-water... Two others had two oranges and a lemon given them each day...Two others took the bigness of nutmeg. The most sudden and visible good effect were perceived from the use of oranges and lemons, one... being fit for duty at six days and the other was appointed nurse to the rest of the sick.
Literatur
1.
Zurück zum Zitat Council MR (1848) Streptomycin treatment of pulmonary tuberculosis. Br Med J 2:769–82 Council MR (1848) Streptomycin treatment of pulmonary tuberculosis. Br Med J 2:769–82
2.
Zurück zum Zitat Sackett DL, Hoey J (2000) Why randomised controlled trials fail but needn’t: a new series is launched. CMAJ 162:1301–1302PubMed Sackett DL, Hoey J (2000) Why randomised controlled trials fail but needn’t: a new series is launched. CMAJ 162:1301–1302PubMed
3.
Zurück zum Zitat Stampfer MJ, Colditz GA (1991) Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the epidemiologic evidence. Prev Med 20:47–63CrossRefPubMed Stampfer MJ, Colditz GA (1991) Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the epidemiologic evidence. Prev Med 20:47–63CrossRefPubMed
4.
Zurück zum Zitat Rossouw JE, Anderson GL, Prentice RL et al (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women’s health initiative randomized controlled trial. JAMA 288:321–333CrossRefPubMed Rossouw JE, Anderson GL, Prentice RL et al (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women’s health initiative randomized controlled trial. JAMA 288:321–333CrossRefPubMed
5.
Zurück zum Zitat LeLorier J, Gregoire G, Benhaddad A, Lapierre J, Derderian F (1997) Discrepancies between meta-analyses and subsequent large randomized, controlled trials. N Engl J Med 337:536–542CrossRefPubMed LeLorier J, Gregoire G, Benhaddad A, Lapierre J, Derderian F (1997) Discrepancies between meta-analyses and subsequent large randomized, controlled trials. N Engl J Med 337:536–542CrossRefPubMed
6.
Zurück zum Zitat Bunker JP, Frazier HS, Mosteller F (1994) Improving health: measuring effects of medical care. Milbank Q 72:225–258PubMedCrossRef Bunker JP, Frazier HS, Mosteller F (1994) Improving health: measuring effects of medical care. Milbank Q 72:225–258PubMedCrossRef
7.
Zurück zum Zitat Bergman A, Elia G (1995) Three surgical procedures for genuine stress incontinence: five-year follow-up of a prospective randomized study. Am J Obstet Gynecol 173:66–71CrossRefPubMed Bergman A, Elia G (1995) Three surgical procedures for genuine stress incontinence: five-year follow-up of a prospective randomized study. Am J Obstet Gynecol 173:66–71CrossRefPubMed
8.
Zurück zum Zitat Benson JT, Lucente V, McClellan E (1996) Vaginal versus abdominal reconstructive surgery for the treatment of pelvic support defects: a prospective randomized study with long-term outcome evaluation. Am J Obstet Gynecol 175:1418–1421CrossRefPubMed Benson JT, Lucente V, McClellan E (1996) Vaginal versus abdominal reconstructive surgery for the treatment of pelvic support defects: a prospective randomized study with long-term outcome evaluation. Am J Obstet Gynecol 175:1418–1421CrossRefPubMed
9.
Zurück zum Zitat Hardiman PJ, Drutz HP (1996) Sacrospinous vault suspension and abdominal colposacropexy: success rates and complications. Am J Obstet Gynecol 175:612–616CrossRefPubMed Hardiman PJ, Drutz HP (1996) Sacrospinous vault suspension and abdominal colposacropexy: success rates and complications. Am J Obstet Gynecol 175:612–616CrossRefPubMed
10.
Zurück zum Zitat Ward KL, Hilton P, Group UKaITT (2004) A prospective multicenter randomized trial of tension-free vaginal tape and colposuspension for primary urodynamic stress incontinence: two-year follow-up. Am J Obstet Gynecol 190:324–331CrossRefPubMed Ward KL, Hilton P, Group UKaITT (2004) A prospective multicenter randomized trial of tension-free vaginal tape and colposuspension for primary urodynamic stress incontinence: two-year follow-up. Am J Obstet Gynecol 190:324–331CrossRefPubMed
1.
Zurück zum Zitat Seaton A (2003) Personal view. BMJ 326 Seaton A (2003) Personal view. BMJ 326
2.
Zurück zum Zitat Herbison P, Hay-Smith J, Ellis K, Moore K (2003) Effectiveness of anticholinergic drugs compared with placebo in the treatment of overactive bladder: systematic review. BMJ 326:841–844CrossRefPubMed Herbison P, Hay-Smith J, Ellis K, Moore K (2003) Effectiveness of anticholinergic drugs compared with placebo in the treatment of overactive bladder: systematic review. BMJ 326:841–844CrossRefPubMed
5.
Zurück zum Zitat Rosenfeld JA (2004) The view of EBM from the trenches: liberation or authoritarian? J Eval Clin Pract 10:153–155CrossRefPubMed Rosenfeld JA (2004) The view of EBM from the trenches: liberation or authoritarian? J Eval Clin Pract 10:153–155CrossRefPubMed
6.
Zurück zum Zitat McCulloch P, Taylor I, Sasako M, Lovett B, Griffin D (2002) Randomised trials in surgery: problems and possible solutions. BMJ 324:1448–1451CrossRefPubMed McCulloch P, Taylor I, Sasako M, Lovett B, Griffin D (2002) Randomised trials in surgery: problems and possible solutions. BMJ 324:1448–1451CrossRefPubMed
7.
Zurück zum Zitat Ward K, Hilton P (2002) UK and Ireland tension-free vaginal tape trial group: prospective multicentre randomised trial of tension-free vaginal tape and colposuspension as primary treatment for stress incontinence. BMJ 325:67–70CrossRefPubMed Ward K, Hilton P (2002) UK and Ireland tension-free vaginal tape trial group: prospective multicentre randomised trial of tension-free vaginal tape and colposuspension as primary treatment for stress incontinence. BMJ 325:67–70CrossRefPubMed
8.
Zurück zum Zitat Maddern GJ, Middleton PF, Grant AM (2002) Urinary stress incontinence: benefits of using tension-free vaginal tape remain unproven. BMJ 325:789–790CrossRefPubMed Maddern GJ, Middleton PF, Grant AM (2002) Urinary stress incontinence: benefits of using tension-free vaginal tape remain unproven. BMJ 325:789–790CrossRefPubMed
9.
Zurück zum Zitat Hilton P (2002) Trials of surgery for stress incontinence—thoughts on the ‘Humpty Dumpty principle’. BJOG 109:1081–1088PubMed Hilton P (2002) Trials of surgery for stress incontinence—thoughts on the ‘Humpty Dumpty principle’. BJOG 109:1081–1088PubMed
10.
Zurück zum Zitat Petri E, Kölbl H (2004) Eminence, or rather eloquence, or rather economy-based medicine? Int Urogynecol J 15:147–148CrossRef Petri E, Kölbl H (2004) Eminence, or rather eloquence, or rather economy-based medicine? Int Urogynecol J 15:147–148CrossRef
11.
Zurück zum Zitat Tamussino K, Hanzal E, Kolle D, Ralph G, Riss PA (2001) Austrian Urogynecology working group: tension-free vaginal tape operation: results of the Austrian registry. Obstet Gynecol 98(1):732–736CrossRefPubMed Tamussino K, Hanzal E, Kolle D, Ralph G, Riss PA (2001) Austrian Urogynecology working group: tension-free vaginal tape operation: results of the Austrian registry. Obstet Gynecol 98(1):732–736CrossRefPubMed
12.
Zurück zum Zitat Kuuva N, Nilsson CG (2002) A nationwide analysis of complications associated with the tension-free vaginal tape (TVT) procedure. Acta Obstet Gynecol Scand 81:72–77CrossRefPubMed Kuuva N, Nilsson CG (2002) A nationwide analysis of complications associated with the tension-free vaginal tape (TVT) procedure. Acta Obstet Gynecol Scand 81:72–77CrossRefPubMed
13.
Zurück zum Zitat Kulseng-Hanssen S (2003) The development of a national database of the results of surgery for urinary incontinence in women. BJOG 110:975–982PubMedCrossRef Kulseng-Hanssen S (2003) The development of a national database of the results of surgery for urinary incontinence in women. BJOG 110:975–982PubMedCrossRef
14.
Zurück zum Zitat Weber AM, Abrams P, Brubaker L, Cundiff G, Davis G, Dmochowski RR, Fischer J, Hull T, Nygaard I, Weidner AC (2001) The standardization of terminology for researchers in female pelvic floor disorders. Int Urogynecol J Pelvic Floor Dysfunct 12:178–186CrossRefPubMed Weber AM, Abrams P, Brubaker L, Cundiff G, Davis G, Dmochowski RR, Fischer J, Hull T, Nygaard I, Weidner AC (2001) The standardization of terminology for researchers in female pelvic floor disorders. Int Urogynecol J Pelvic Floor Dysfunct 12:178–186CrossRefPubMed
Metadaten
Titel
The need for randomised controlled trials in urogynaecology
verfasst von
Christopher Maher
Bernhard Schuessler
Publikationsdatum
01.08.2006
Verlag
Springer-Verlag
Erschienen in
International Urogynecology Journal / Ausgabe 4/2006
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-005-0029-y

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