01.08.2006 | Controversies in Urogynecology
The need for randomised controlled trials in urogynaecology
Erschienen in: International Urogynecology Journal | Ausgabe 4/2006
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Research in urogynaecology is aimed at acquiring knowledge to improve the outcomes of the women that we treat. Confucius in 479 b.c. stated that the essence of knowledge is, having it, to apply it. Since that time, clinicians and researchers alike have searched for the truth. As early as 1747, James Lind performed a planned trial on scurvy:…I took 12 patients in the scurvy on board the Salisbury at sea. The cases were as similar as I could have them.... They lay together and had one diet common to them all. Two of these were ordered a quart of cider per day... two others took two spoonfuls of vinegar... Two were put on a course of sea-water... Two others had two oranges and a lemon given them each day...Two others took the bigness of nutmeg. The most sudden and visible good effect were perceived from the use of oranges and lemons, one... being fit for duty at six days and the other was appointed nurse to the rest of the sick.