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Osteoporosis International

Erschienen in:

01.07.2005 | Editorial

Estimates of optimal vitamin D status

verfasst von: Bess Dawson-Hughes, Robert P. Heaney, Michael F. Holick, Paul Lips, Pierre J. Meunier, Reinhold Vieth

Erschienen in: Osteoporosis International | Ausgabe 7/2005

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Abstract

Vitamin D has captured attention as an important determinant of bone health, but there is no common definition of optimal vitamin D status. Herein, we address the question: What is the optimal circulating level of 25-hydroxyvitamin D [25(OH)D] for the skeleton? The opinions of the authors on the minimum level of serum 25(OH)D that is optimal for fracture prevention varied between 50 and 80 nmol/l. However, for five of the six authors, the minimum desirable 25(OH)D concentration clusters between 70 and 80 nmol/l. The authors recognize that the average older man and woman will need intakes of at least 20 to 25 mcg (800 to 1,000 IU) per day of vitamin D₃to reach a serum 25(OH)D level of 75 nmol/l. Based on the available evidence, we believe that if older men and women maintain serum levels of 25(OH)D that are higher than the consensus median threshold of 75 nmol/l, they will be at lower risk of fracture.

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Titel: Estimates of optimal vitamin D status
verfasst von: Bess Dawson-Hughes
Robert P. Heaney
Michael F. Holick
Paul Lips
Pierre J. Meunier
Reinhold Vieth
Publikationsdatum: 01.07.2005
Verlag: Springer-Verlag
Erschienen in: Osteoporosis International / Ausgabe 7/2005
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-005-1867-7

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