Erschienen in:
01.02.2007 | Hot Stuff
The periosteum—a surface for all seasons
verfasst von:
E. Seeman
Erschienen in:
Osteoporosis International
|
Ausgabe 2/2007
Einloggen, um Zugang zu erhalten
Excerpt
Fetal limb buds removed in utero and grown ex vivo develop the shape of the proximal femur [
1]. Thus, the structure needed to accommodate the stresses to be borne is assembled by instructions from the ancestorial genetic ‘blue print’. Although this seems obvious, it is considerably less obvious that the reverse also applies; the stresses imposed on bone determine its material composition, structural design and so its strength [
2]. Bone has the ability to adapt—to modify its material composition and structural design to accommodate prevailing loads. …