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Osteoporosis International

Erschienen in:

01.07.2009 | Original Article

Measurement of human trabecular bone by novel ultrasonic bone densitometry based on fast and slow waves

verfasst von: T. Yamamoto, T. Otani, H. Hagino, H. Katagiri, T. Okano, I. Mano, R. Teshima

Erschienen in: Osteoporosis International | Ausgabe 7/2009

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Abstract

Summary

Two longitudinal transmitted waves, fast and slow waves, were observed by employing a new quantitative ultrasound (QUS) method. The trabecular bone measurements generated by this method reflect three-dimensional structural information, and the new QUS parameters were able to identify vertebral fractures.

Introduction

The aims were to identify new quantitative ultrasound (QUS) parameters that based on new QUS method reflecting not only bone volume but also the microstructures of trabecular bone ex vivo and to observe how much they predict fracture risk in vivo.

Methods

Ex vivo measurement: Three human femoral heads were used for the experiment. Attenuation of the slow wave, attenuation of the fast wave, speed of the slow wave, speed of the fast wave (SOFW), bone mass density of trabecular bone, and elastic modulus of the trabecular bone (EMTb) of each specimen were obtained using a new QUS method and compared with three-dimensional structural parameters measured by micro-computed tomography. In vivo measurement: Eighty-nine volunteers were enrolled, and the bone status in the distal radius was measured using a new QUS method. These parameters were compared with data evaluated by peripheral quantitative computed tomography and dual X-ray absorptiometry.

Results

Ex vivo measurement: SOFW and EMTb showed correlations with the parameter of trabecular anisotropy. In vivo measurement: The new QUS parameters were able to identify vertebral fractures.

Conclusion

The newly developed QUS technique reflects the three-dimensional structure and is a promising method to evaluate fracture risk.

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Titel: Measurement of human trabecular bone by novel ultrasonic bone densitometry based on fast and slow waves
verfasst von: T. Yamamoto
T. Otani
H. Hagino
H. Katagiri
T. Okano
I. Mano
R. Teshima
Publikationsdatum: 01.07.2009
Verlag: Springer-Verlag
Erschienen in: Osteoporosis International / Ausgabe 7/2009
Print ISSN: 0937-941X
Elektronische ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-008-0774-0

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Measurement of human trabecular bone by novel ultrasonic bone densitometry based on fast and slow waves

Abstract

Summary

Introduction

Methods

Results

Conclusion

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Abstract

Summary

Introduction

Methods

Results

Conclusion

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