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European Journal of Nuclear Medicine and Molecular Imaging

Erschienen in:

01.11.2009 | Original Article

Prognostic risk stratification of myocardial ischaemia evaluated by gated myocardial perfusion SPECT in patients with chronic kidney disease

verfasst von: Tsuguru Hatta, Shigeyuki Nishimura, Tsunehiko Nishimura

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 11/2009

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Abstract

Purpose

The aim of this study was to identify useful predictors of cardiac events in patients with chronic kidney disease (CKD).

Methods

Among 4,031 patients identified from the Japanese Assessment of Cardiac Events and Survival Study (J-ACCESS) database with suspected or known ischaemic heart disease, we selected 820 with an estimated glomerular filtration rate (eGFR) of < 60 ml/min per 1.73 m².

Results

A total of 75 cardiac events developed among these 820 patients. The incidence of cardiac events was higher in the group with a lower eGFR. Multivariate Cox analysis indicated that age, diabetes mellitus, end-systolic volume, summed stress score (SSS) and eGFR were predictors of cardiac events. Event rates of patients with SSS ≥ 9 were significantly higher in groups with lower eGFR values (< 40 and 40–49 ml/min).

Conclusion

The SSS value (≥ 9) is a reliable predictor of cardiac events and myocardial single photon emission computed tomography has incremental value for predicting cardiac events and survival in CKD.

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Titel: Prognostic risk stratification of myocardial ischaemia evaluated by gated myocardial perfusion SPECT in patients with chronic kidney disease
verfasst von: Tsuguru Hatta
Shigeyuki Nishimura
Tsunehiko Nishimura
Publikationsdatum: 01.11.2009
Verlag: Springer-Verlag
Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 11/2009
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-009-1165-2

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusion

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