Erschienen in:
11.08.2020 | Image of the Month
A theranostic approach of [68Ga]Ga-DOTA.SA.FAPi PET/CT-guided [177Lu]Lu-DOTA.SA.FAPi radionuclide therapy in an end-stage breast cancer patient: new frontier in targeted radionuclide therapy
verfasst von:
Sanjana Ballal, Madhav Prasad Yadav, Vasko Kramer, Euy Sung Moon, Frank Roesch, Madhav Tripathi, Soumyaranjan Mallick, Sreedharan Thankarajan ArunRaj, Chandrasekhar Bal
Erschienen in:
European Journal of Nuclear Medicine and Molecular Imaging
|
Ausgabe 3/2021
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Excerpt
A 31-year-young female was diagnosed with breast cancer in September 2019. The histopathology revealed atypical cells arranged cords and tubules in the fibrotic stroma suggestive of invasive ductal carcinoma of the breast and the immunohistochemistry reported cells immunopositive for Her2neu, while negative for ER and PR (Fig. 1a). The patient underwent all the standard lines of treatment; however, during treatment, she experienced a new onset of headaches and seizures. A follow-up [18F]F-FDG PET/CT was performed (Fig. 1b) on a dedicated GE Discovery 710* 128 Slice PET/CT Scanner, in which the maximum-intensity projection image (MIP) (Fig. 1b) revealed evidence of extensive involvement of disease in known sites, namely, the loco-regional, lungs, liver and bones. However, due to the detection of a new brain lesion, the patient was classified as having a progressive disease (Fig. 1b). …
