Skip to main content
Erschienen in: International Orthopaedics 7/2015

01.07.2015 | Original Paper

Full weight bearing and dynamisation with Limmed® locked plate fixation accelerates bone regeneration in the volume of opening wedge high tibial osteotomy

verfasst von: Philippe Hernigou, Charles Flouzat Lachaniette, Jerome Delambre, Isaac Guissou, Omar Dahmani, Mohamed Ibrahim Ouali, Alexandre Poignard

Erschienen in: International Orthopaedics | Ausgabe 7/2015

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The efficacy of immediate full weight bearing in accelerating bone regeneration after medial opening wedge high tibial osteotomy (HTO) was evaluated in patients operated with the Limmed system (locked plate fixation) that allows dynamisation of the site of the osteotomy.

Methods

A case series of 50 consecutive osteotomies performed with Limmed locked plate fixation for medial opening wedge HTO had full weight bearing immediately after the HTO; they were compared to a case-matched control series of 50 HTOs (50 patients) performed using the same implant without locked screws. Radiographs were observed at 30 days and two, three, four, five and six months after surgery. The osteotomy gap was only partially filled by a medial bone substitute leaving the lateral part unfilled. Bone surface areas of osteotomy planes were quantified and opening volumes were determined applying wedge heights. End points for evaluation included radiographic evidence of bone regeneration in the volume created by the opening of the osteotomy.

Results

Statistically significant differences were seen between the groups in terms of radiographic union and radiographic stability between the two groups. Patients of the Limmed group reported a shorter time for union (average four weeks difference) without loss of correction during healing. At the radiographic evaluation, there was a significant increase in osseointegration in the group with weight bearing compared to the control group without weight bearing with increased rate of speed to fill the void volume of the osteotomy. The computed tomography scan of the grafted area at four months after surgery showed no significant difference in the quality of the newly formed bone between the two groups.

Conclusions

The Limmed medial opening wedge HTO system with immediate full weight bearing accelerates bone graft substitute osseointegration and bone healing as compared with controls without full weight bearing.
Literatur
1.
Zurück zum Zitat Benzakour T, Hefti A, Lemseffer M, El Ahmadi JD, Bouyarmane H, Benzakour A (2010) High tibial osteotomy for medial osteoarthritis of the knee: 15 years follow-up. Int Orthop 34(2):209–215PubMedCentralPubMedCrossRef Benzakour T, Hefti A, Lemseffer M, El Ahmadi JD, Bouyarmane H, Benzakour A (2010) High tibial osteotomy for medial osteoarthritis of the knee: 15 years follow-up. Int Orthop 34(2):209–215PubMedCentralPubMedCrossRef
2.
Zurück zum Zitat Bode G, Ogon P, Pestka J, Zwingmann J, Feucht M, Südkamp N, Niemeyer P (2014) Clinical outcome and return to work following single-stage combined autologous chondrocyte implantation and high tibial osteotomy. Int Orthop. Oct 10. PMID: 25300396 Bode G, Ogon P, Pestka J, Zwingmann J, Feucht M, Südkamp N, Niemeyer P (2014) Clinical outcome and return to work following single-stage combined autologous chondrocyte implantation and high tibial osteotomy. Int Orthop. Oct 10. PMID: 25300396
3.
Zurück zum Zitat Brinkman JM, Luites JW, Wymenga AB, van Heerwaarden RJ (2010) Early full weight bearing is safe in open-wedge high tibial osteotomy. Acta Orthop 81(2):193–198PubMedCentralPubMedCrossRef Brinkman JM, Luites JW, Wymenga AB, van Heerwaarden RJ (2010) Early full weight bearing is safe in open-wedge high tibial osteotomy. Acta Orthop 81(2):193–198PubMedCentralPubMedCrossRef
4.
Zurück zum Zitat Brosset T, Pasquier G, Migaud H, Gougeon F (2011) Opening wedge high tibial osteotomy performed without filling the defect but with locking plate fixation (TomoFix™) and early weight-bearing: prospective evaluation of bone union, precision and maintenance of correction in 51 cases. Orthop Traumatol Surg Res 97:705–711 Brosset T, Pasquier G, Migaud H, Gougeon F (2011) Opening wedge high tibial osteotomy performed without filling the defect but with locking plate fixation (TomoFix™) and early weight-bearing: prospective evaluation of bone union, precision and maintenance of correction in 51 cases. Orthop Traumatol Surg Res 97:705–711
5.
Zurück zum Zitat Caton J (1989) Method of measuring the height of the patella. Acta Orthop Belg 55:385–386PubMed Caton J (1989) Method of measuring the height of the patella. Acta Orthop Belg 55:385–386PubMed
6.
Zurück zum Zitat Floerkemeier S, Staubli AE, Schroeter S, Goldhahn S, Lobenhoffer P (2014) Does obesity and nicotine abuse influence the outcome and complication rate after open-wedge high tibial osteotomy? A retrospective evaluation of five hundred and thirty three patients. Int Orthop 38(1):55–60PubMedCentralPubMedCrossRef Floerkemeier S, Staubli AE, Schroeter S, Goldhahn S, Lobenhoffer P (2014) Does obesity and nicotine abuse influence the outcome and complication rate after open-wedge high tibial osteotomy? A retrospective evaluation of five hundred and thirty three patients. Int Orthop 38(1):55–60PubMedCentralPubMedCrossRef
7.
Zurück zum Zitat Goodship AE, Kenwright J (1985) The influence of induced micromovement upon the healing of experimental tibial fractures. J Bone Joint Surg Br 67:650–655PubMed Goodship AE, Kenwright J (1985) The influence of induced micromovement upon the healing of experimental tibial fractures. J Bone Joint Surg Br 67:650–655PubMed
8.
Zurück zum Zitat Hernigou P, Medevielle D, Debeyre J, Goutallier D (1987) Proximal tibial osteotomy for osteoarthritis with varus deformity. A ten to thirteen-year follow-up study. J Bone Joint Surg Am 69(3):332–354PubMed Hernigou P, Medevielle D, Debeyre J, Goutallier D (1987) Proximal tibial osteotomy for osteoarthritis with varus deformity. A ten to thirteen-year follow-up study. J Bone Joint Surg Am 69(3):332–354PubMed
9.
Zurück zum Zitat Hernigou P, Roussignol X, Flouzat-Lachaniette CH, Filippini P, Guissou I, Poignard A (2010) Opening wedge tibial osteotomy for large varus deformity with Ceraver resorbable beta tricalcium phosphate wedges. Int Orthop 34(2):191–199PubMedCentralPubMedCrossRef Hernigou P, Roussignol X, Flouzat-Lachaniette CH, Filippini P, Guissou I, Poignard A (2010) Opening wedge tibial osteotomy for large varus deformity with Ceraver resorbable beta tricalcium phosphate wedges. Int Orthop 34(2):191–199PubMedCentralPubMedCrossRef
10.
Zurück zum Zitat Hernigou P, Queinnec S, Picard L, Guissou I, Naanaa T, Duffiet P, Julian D, Archer V (2013) Safety of a novel high tibial osteotomy locked plate fixation for immediate full weight-bearing: a case–control study. Int Orthop 37(12):2377–2384PubMedCentralPubMedCrossRef Hernigou P, Queinnec S, Picard L, Guissou I, Naanaa T, Duffiet P, Julian D, Archer V (2013) Safety of a novel high tibial osteotomy locked plate fixation for immediate full weight-bearing: a case–control study. Int Orthop 37(12):2377–2384PubMedCentralPubMedCrossRef
11.
Zurück zum Zitat Koshino T, Murase T, Saito T (2003) Medial opening-wedge high tibial osteotomy with use of porous hydroxyapatite to treat medial compartment osteoarthritis of the knee. J Bone Joint Surg Am 85-A:78–85PubMed Koshino T, Murase T, Saito T (2003) Medial opening-wedge high tibial osteotomy with use of porous hydroxyapatite to treat medial compartment osteoarthritis of the knee. J Bone Joint Surg Am 85-A:78–85PubMed
12.
Zurück zum Zitat Nelissen EM, van Langelaan EJ, Nelissen RG (2010) Stability of medial opening wedge high tibial osteotomy: a failure analysis. Int Orthop 34(2):217–223PubMedCentralPubMedCrossRef Nelissen EM, van Langelaan EJ, Nelissen RG (2010) Stability of medial opening wedge high tibial osteotomy: a failure analysis. Int Orthop 34(2):217–223PubMedCentralPubMedCrossRef
13.
Zurück zum Zitat Paley D, Fleming B, Catagni M, Kristiansen T, Pope M (1990) Mechanical evaluation of external fixators used in limb lengthening. Clin Orthop 250:50–57PubMed Paley D, Fleming B, Catagni M, Kristiansen T, Pope M (1990) Mechanical evaluation of external fixators used in limb lengthening. Clin Orthop 250:50–57PubMed
14.
Zurück zum Zitat Perren SM (2008) Fracture healing. The evolution of our understanding. Acta Chir Orthop Traumatol Cech 75:241–246PubMed Perren SM (2008) Fracture healing. The evolution of our understanding. Acta Chir Orthop Traumatol Cech 75:241–246PubMed
15.
Zurück zum Zitat Poignard A, Flouzat Lachaniette CH, Amzallag J, Hernigou P (2010) Revisiting high tibial osteotomy: fifty years of experience with the opening-wedge technique. J Bone Joint Surg Am 92(Suppl 2):187–195PubMedCrossRef Poignard A, Flouzat Lachaniette CH, Amzallag J, Hernigou P (2010) Revisiting high tibial osteotomy: fifty years of experience with the opening-wedge technique. J Bone Joint Surg Am 92(Suppl 2):187–195PubMedCrossRef
16.
Zurück zum Zitat Ralston JL, Brown TD, Nepola JV, Williams DR, Marsh JL (1990) Mechanical analysis of the factors affecting dynamization of the Orthofix Dynamic Axial Fixator. J Orthop Trauma 4:449–457PubMedCrossRef Ralston JL, Brown TD, Nepola JV, Williams DR, Marsh JL (1990) Mechanical analysis of the factors affecting dynamization of the Orthofix Dynamic Axial Fixator. J Orthop Trauma 4:449–457PubMedCrossRef
17.
Zurück zum Zitat Richardson JB, Cunningham iL, Goodship AE, O’Connor BT, Kenwright J (1994) Measuring stiffness can define healing of tibial fractures. J Bone Joint Surg Br 76:389–394PubMed Richardson JB, Cunningham iL, Goodship AE, O’Connor BT, Kenwright J (1994) Measuring stiffness can define healing of tibial fractures. J Bone Joint Surg Br 76:389–394PubMed
18.
Zurück zum Zitat Santic V, Tudor A, Sestan B, Legovic D, Sirola L, Rakovac I (2010) Bone allograft provides bone healing in the medial opening high tibial osteotomy. Int Orthop 34(2):225–229PubMedCentralPubMedCrossRef Santic V, Tudor A, Sestan B, Legovic D, Sirola L, Rakovac I (2010) Bone allograft provides bone healing in the medial opening high tibial osteotomy. Int Orthop 34(2):225–229PubMedCentralPubMedCrossRef
19.
Zurück zum Zitat Saragaglia D, Blaysat M, Inman D, Mercier N (2011) Outcome of opening wedge high tibial osteotomy augmented with a Biosorb® wedge and fixed with a plate and screws in 124 patients with a mean of ten years follow-up. Int Orthop 35(8):1151–1156PubMedCentralPubMedCrossRef Saragaglia D, Blaysat M, Inman D, Mercier N (2011) Outcome of opening wedge high tibial osteotomy augmented with a Biosorb® wedge and fixed with a plate and screws in 124 patients with a mean of ten years follow-up. Int Orthop 35(8):1151–1156PubMedCentralPubMedCrossRef
20.
Zurück zum Zitat Schallberger A, Jacobi M, Wahl P, Maestretti G, Jakob RP (2011) High tibial valgus osteotomy in unicompartmental medial osteoarthritis of the knee: a retrospective follow-up study over 13–21 years. Knee Surg Sports Traumatol Arthrosc 19:122–127PubMedCrossRef Schallberger A, Jacobi M, Wahl P, Maestretti G, Jakob RP (2011) High tibial valgus osteotomy in unicompartmental medial osteoarthritis of the knee: a retrospective follow-up study over 13–21 years. Knee Surg Sports Traumatol Arthrosc 19:122–127PubMedCrossRef
21.
Zurück zum Zitat Schenk RK, Willenegger HR (1977) Histology of primary bone healing: modifications and limits of recovery of gaps in relation to the extent of the defect. Unfallheilkunde 80:155–160PubMed Schenk RK, Willenegger HR (1977) Histology of primary bone healing: modifications and limits of recovery of gaps in relation to the extent of the defect. Unfallheilkunde 80:155–160PubMed
22.
Zurück zum Zitat Staubli AE (2008) Radiological examination of bone healing after open-wedge tibial osteotomy. In: Lobenhoffer P, van Heerwaarden RJ, Staubli AE, Jacobs WC (eds) Osteotomies around the knee. Thieme, Stuttgart, pp 131–146 Staubli AE (2008) Radiological examination of bone healing after open-wedge tibial osteotomy. In: Lobenhoffer P, van Heerwaarden RJ, Staubli AE, Jacobs WC (eds) Osteotomies around the knee. Thieme, Stuttgart, pp 131–146
23.
Zurück zum Zitat Staubli AE, Jacob HA (2010) Evolution of open-wedge high-tibial osteotomy: experience with a special angular stable device for internal fixation without interposition material. Int Orthop 34:167–172PubMedCentralPubMedCrossRef Staubli AE, Jacob HA (2010) Evolution of open-wedge high-tibial osteotomy: experience with a special angular stable device for internal fixation without interposition material. Int Orthop 34:167–172PubMedCentralPubMedCrossRef
24.
Zurück zum Zitat Staubli AE, De Simoni C, Babst R, Lobenhoffer P (2003) TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia—early results in 92 cases. Injury 34(Suppl 2):B55–B62PubMedCrossRef Staubli AE, De Simoni C, Babst R, Lobenhoffer P (2003) TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia—early results in 92 cases. Injury 34(Suppl 2):B55–B62PubMedCrossRef
25.
Zurück zum Zitat Takeuchi R, Ishikawa H, Aratake M et al (2009) Medial opening wedge high tibial osteotomy with early full weight bearing. Arthroscopy 25:46–53PubMedCrossRef Takeuchi R, Ishikawa H, Aratake M et al (2009) Medial opening wedge high tibial osteotomy with early full weight bearing. Arthroscopy 25:46–53PubMedCrossRef
Metadaten
Titel
Full weight bearing and dynamisation with Limmed® locked plate fixation accelerates bone regeneration in the volume of opening wedge high tibial osteotomy
verfasst von
Philippe Hernigou
Charles Flouzat Lachaniette
Jerome Delambre
Isaac Guissou
Omar Dahmani
Mohamed Ibrahim Ouali
Alexandre Poignard
Publikationsdatum
01.07.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
International Orthopaedics / Ausgabe 7/2015
Print ISSN: 0341-2695
Elektronische ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-014-2633-2

Weitere Artikel der Ausgabe 7/2015

International Orthopaedics 7/2015 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.