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01.04.2011 | Case Report

Development of antisynthetase syndrome in a patient with rheumatoid arthritis

verfasst von: Cheol-Kyu Park, Tae-Jong Kim, Young-Nan Cho, Il-Soo Kim, Ho-Jun Lee, Kyung-Eun Lee, Seong-Chang Park, Jong-Sun Kim, Dong-Jin Park, Sung-Ji Lee, Seong-Rye Seo, Jeong-Chul Kim, Sang-Gook Song, Shin-Seok Lee, Yong-Wook Park

Erschienen in: Rheumatology International | Ausgabe 4/2011

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Abstract

Rheumatoid arthritis (RA) and antisynthetase syndrome (ASS) are distinct clinical syndromes, and their co-occurrence is rarely encountered. The authors report the case of a 56-year-old female patient with RA of 3 years duration who suddenly developed ASS, and include a review of the literature. The patient was diagnosed with ASS based on; positivity for anti-histidyl-tRNA synthetase (Jo-1) antibody, interstitial lung disease, polyarthritis, and mechanic’s hands. High-dose corticosteroid and pulse intravenous cyclophosphamide were used to control the ASS. This case demonstrates that ASS should be considered during clinical presentations due to its potential overlap with RA.

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Titel: Development of antisynthetase syndrome in a patient with rheumatoid arthritis
verfasst von: Cheol-Kyu Park
Tae-Jong Kim
Young-Nan Cho
Il-Soo Kim
Ho-Jun Lee
Kyung-Eun Lee
Seong-Chang Park
Jong-Sun Kim
Dong-Jin Park
Sung-Ji Lee
Seong-Rye Seo
Jeong-Chul Kim
Sang-Gook Song
Shin-Seok Lee
Yong-Wook Park
Publikationsdatum: 01.04.2011
Verlag: Springer-Verlag
Erschienen in: Rheumatology International / Ausgabe 4/2011
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-009-1222-y

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