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Erschienen in: Archives of Orthopaedic and Trauma Surgery 9/2008

01.09.2008 | Trauma Surgery

Timing of thoracolomber spine stabilization in trauma patients; impact on neurological outcome and clinical course. A real prospective (rct) randomized controlled study

verfasst von: Şahika Liva Cengiz, Erdal Kalkan, Aysegul Bayir, Kemal Ilik, Alper Basefer

Erschienen in: Archives of Orthopaedic and Trauma Surgery | Ausgabe 9/2008

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Abstract

Objective

Optimal timing of stabilization for spinal injuries is discussed controversially. The goal of this study is to investigate the neurological recovery and its influencing factors in thoracolumbar spine fractures after surgical decompression and stabilization within 8 h of spinal cord injury versus surgery which is performed between 3 and 15 days.

Methods

Twenty-seven patients undergoing thoracolumbar stabilization with neurological deficit for an acute thoracolumbar spinal injury at the level of Th8-L2 vertebra at Selcuk University between March 2004 and December 2006 were recorded. Patients with neurological deficity and medically stable for surgery underwent immediate stabilization within 8 h defined as group I (n = 12) and patients underwent operation in 3–15 days after thoracolumbar injury were defined as group II (n = 15). Patients were assessed for neurologic deficit and improvement as defined by the scoring system of American spinal injury association (ASIA).

Results

In spite of comparable demographic data, patients in group I had a significantly shorter overall hospital and intensive care unit stay and had lesser systemic complications such as pneumonia and also exhibited better neurological improvement than group II (p < 0.05).

Conclusion

Early surgery may improve neurological recovery and decrease hospitalization time and also additional systemic complications in patients with thoracolomber spinal cord injuries. Thus early stabilization of thoracolumbar spine fractures within 8 h after trauma appears to be favorable.
Literatur
1.
Zurück zum Zitat Jacobs RR, Casey MP (1984) Surgical management of thoracolumbar spinal injuries. Clin Orthop 189:22–35PubMed Jacobs RR, Casey MP (1984) Surgical management of thoracolumbar spinal injuries. Clin Orthop 189:22–35PubMed
2.
Zurück zum Zitat Magerl FP (1984) Stabilization of the lower thoracic and lumbar spine with external skeletal fixation. Clin Orthop 189:125–141PubMed Magerl FP (1984) Stabilization of the lower thoracic and lumbar spine with external skeletal fixation. Clin Orthop 189:125–141PubMed
3.
Zurück zum Zitat Silvestro C, Francaviglia N, Bragazzi R, Viale GL (1992) Near anatomical reduction and stabilization of burst fractures of the lower thoracic or lumbar spine. Acta Neurochir 116:53–59CrossRef Silvestro C, Francaviglia N, Bragazzi R, Viale GL (1992) Near anatomical reduction and stabilization of burst fractures of the lower thoracic or lumbar spine. Acta Neurochir 116:53–59CrossRef
4.
Zurück zum Zitat Fehlings MG, Perrin RG (2005) The role and timing of early decompression for cervical spinal cord injury: update with a review of recent clinical evidence. Injury 2:13–26CrossRef Fehlings MG, Perrin RG (2005) The role and timing of early decompression for cervical spinal cord injury: update with a review of recent clinical evidence. Injury 2:13–26CrossRef
5.
Zurück zum Zitat Kerwin AJ, Frykberg ER, Schinco MA, Griffen MM, Murphy T, Tepas JJ (2005) The effect of early spine fixation on non-neurologic outcome. J Trauma 58:15–21PubMed Kerwin AJ, Frykberg ER, Schinco MA, Griffen MM, Murphy T, Tepas JJ (2005) The effect of early spine fixation on non-neurologic outcome. J Trauma 58:15–21PubMed
6.
Zurück zum Zitat Mirza SK, Krengel WF 3rd, Chapman JR, Anderson PA, Bailey JC, Grady MS et al (1999) Early versus delayed surgery for acute cervical spinal cord injury. Clin Orthop Relat Res 359:104–114PubMedCrossRef Mirza SK, Krengel WF 3rd, Chapman JR, Anderson PA, Bailey JC, Grady MS et al (1999) Early versus delayed surgery for acute cervical spinal cord injury. Clin Orthop Relat Res 359:104–114PubMedCrossRef
7.
Zurück zum Zitat Rath SA, Kahamba JF, Kretschmer T, Neff U, Richter HP, Antoniadis G (2005) Neurological recovery and its influencing factors in thoracic and lumbar spine fractures after surgical decompression and stabilization. Neurosurg Rev 28:44–52PubMed Rath SA, Kahamba JF, Kretschmer T, Neff U, Richter HP, Antoniadis G (2005) Neurological recovery and its influencing factors in thoracic and lumbar spine fractures after surgical decompression and stabilization. Neurosurg Rev 28:44–52PubMed
8.
Zurück zum Zitat Schinkel C, Frangen TM, Kmetic A, Andress HJ, Muhr G (2006) Timing of thoracic spine stabilization in trauma patients: impact on clinical course and outcome. J Trauma 61:156–160PubMed Schinkel C, Frangen TM, Kmetic A, Andress HJ, Muhr G (2006) Timing of thoracic spine stabilization in trauma patients: impact on clinical course and outcome. J Trauma 61:156–160PubMed
9.
Zurück zum Zitat Riska EB, von Bonsdorff H, Hakkinen S, Jaroma H, Kiviluoto O, Paavilainen T (1977) Primary operative fixation of long bone fractures in patients with multiple injuries. J Trauma 17:111–121PubMed Riska EB, von Bonsdorff H, Hakkinen S, Jaroma H, Kiviluoto O, Paavilainen T (1977) Primary operative fixation of long bone fractures in patients with multiple injuries. J Trauma 17:111–121PubMed
10.
Zurück zum Zitat Seibel R, LaDuca J, Hassett JM, Babikian G, Mills B, Border DO et al (1985) Blunt multiple trauma (ISS 36), femur traction, and the pulmonary failure-septic state. Ann Surg 202:283–295PubMedCrossRef Seibel R, LaDuca J, Hassett JM, Babikian G, Mills B, Border DO et al (1985) Blunt multiple trauma (ISS 36), femur traction, and the pulmonary failure-septic state. Ann Surg 202:283–295PubMedCrossRef
11.
Zurück zum Zitat Aebi M, Mohler J, Zach GA, Morscher E (1986) Indication, surgical technique, and results of 100 surgically-treated fractures and fracture–dislocations of the cervical spine. Clin Orthop Relat Res 203:244–257PubMed Aebi M, Mohler J, Zach GA, Morscher E (1986) Indication, surgical technique, and results of 100 surgically-treated fractures and fracture–dislocations of the cervical spine. Clin Orthop Relat Res 203:244–257PubMed
12.
Zurück zum Zitat Burke DC, Berryman D (1971) The place of closed manipulation in the management of flexion–rotation dislocations of the cervical spine. J Bone Joint Surg Br 53:165–182PubMed Burke DC, Berryman D (1971) The place of closed manipulation in the management of flexion–rotation dislocations of the cervical spine. J Bone Joint Surg Br 53:165–182PubMed
13.
Zurück zum Zitat Krengel WF 3rd, Anderson PA, Henley MB (1993) Early stabilization and decompression for incomplete paraplegia due to a thoracic-level spinal cord injury. Spine 15:2080–2087CrossRef Krengel WF 3rd, Anderson PA, Henley MB (1993) Early stabilization and decompression for incomplete paraplegia due to a thoracic-level spinal cord injury. Spine 15:2080–2087CrossRef
14.
Zurück zum Zitat Marshall LF, Knowlton S, Garfin SR, Klauber MR, Eisenberg HM, Kopaniky D et al (1987) Deterioration following spinal cord injury. J Neurosurg 66:400–404PubMed Marshall LF, Knowlton S, Garfin SR, Klauber MR, Eisenberg HM, Kopaniky D et al (1987) Deterioration following spinal cord injury. J Neurosurg 66:400–404PubMed
15.
Zurück zum Zitat Vaccaro AR, Daugherty RJ, Sheehan TP, Dante SJ, Cotler JM, Balderston RA et al (1997) Neurologic outcome of early versus late surgery for cervical spinal cord injury. Spine 15:2609–2613CrossRef Vaccaro AR, Daugherty RJ, Sheehan TP, Dante SJ, Cotler JM, Balderston RA et al (1997) Neurologic outcome of early versus late surgery for cervical spinal cord injury. Spine 15:2609–2613CrossRef
16.
Zurück zum Zitat Tator CH (2006) Review of treatment trials in human spinal cord injury: issues, difficulties, and recommendations. Neurosurgery 59:957–82PubMed Tator CH (2006) Review of treatment trials in human spinal cord injury: issues, difficulties, and recommendations. Neurosurgery 59:957–82PubMed
17.
Zurück zum Zitat Tator CH (1996) Pathophysiology and pathology of spinal cord injury. In: Wilkins RH, Rengachary SS (eds) Neurosurgery. McGraw-Hill, New York, pp 2847–2859 Tator CH (1996) Pathophysiology and pathology of spinal cord injury. In: Wilkins RH, Rengachary SS (eds) Neurosurgery. McGraw-Hill, New York, pp 2847–2859
18.
Zurück zum Zitat Leypold BG, Flanders AE, Schwartz ED, Burns AS (2007) The impact of methylprednisolone on lesion severity following spinal cord injury. Spine 32:373–378PubMedCrossRef Leypold BG, Flanders AE, Schwartz ED, Burns AS (2007) The impact of methylprednisolone on lesion severity following spinal cord injury. Spine 32:373–378PubMedCrossRef
19.
Zurück zum Zitat Magerl F, Aebi M, Gertzbein SD, Harms J, Nazarian SA (1994) Comprehensive classification of thoracic and lumbar injuries. Eur Spine J 3:184–201PubMedCrossRef Magerl F, Aebi M, Gertzbein SD, Harms J, Nazarian SA (1994) Comprehensive classification of thoracic and lumbar injuries. Eur Spine J 3:184–201PubMedCrossRef
20.
Zurück zum Zitat Harrop JS, Sharan A, Ratliff J (2006) Central cord injury: pathophysiology, management, and outcomes. Spine J 6:198–206CrossRef Harrop JS, Sharan A, Ratliff J (2006) Central cord injury: pathophysiology, management, and outcomes. Spine J 6:198–206CrossRef
21.
Zurück zum Zitat Maynard FM Jr, Bracken MB, Creasey G, Ditunno JF Jr, Donovan WH, Ducker TB et al (1997) International standards for neurological and functional classification of spinal cord injury. Spinal Cord 35:266–274PubMedCrossRef Maynard FM Jr, Bracken MB, Creasey G, Ditunno JF Jr, Donovan WH, Ducker TB et al (1997) International standards for neurological and functional classification of spinal cord injury. Spinal Cord 35:266–274PubMedCrossRef
22.
Zurück zum Zitat Bracken MB, Holford TR (1993) Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2. J. Neurosurgery 79:500–507CrossRef Bracken MB, Holford TR (1993) Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2. J. Neurosurgery 79:500–507CrossRef
23.
Zurück zum Zitat Delamarter RB, Sherman J, Carr JB (1995) Pathophysiology of spinal cord injury. Recovery after immediate and delayed decompression. J Bone Joint Surg Am 77:1042–1049PubMed Delamarter RB, Sherman J, Carr JB (1995) Pathophysiology of spinal cord injury. Recovery after immediate and delayed decompression. J Bone Joint Surg Am 77:1042–1049PubMed
24.
Zurück zum Zitat Fehlings MG, Tator CH (1999) An evidence-based review of decompressive surgery in acute spinal cord injury: rationale, indications, and timing based on experimental and clinical studies. J Neurosurg 91:1–11PubMed Fehlings MG, Tator CH (1999) An evidence-based review of decompressive surgery in acute spinal cord injury: rationale, indications, and timing based on experimental and clinical studies. J Neurosurg 91:1–11PubMed
25.
Zurück zum Zitat Guha A, Tator CH, Endrenyi L, Piper I (1987) Decompression of the spinal cord improves recovery after acute experimental spinal cord compression injury. Paraplegia 25:324–339PubMed Guha A, Tator CH, Endrenyi L, Piper I (1987) Decompression of the spinal cord improves recovery after acute experimental spinal cord compression injury. Paraplegia 25:324–339PubMed
26.
Zurück zum Zitat McAfee PC, Bohlman HH, Yuan HA (1985) Anterior decompression of traumatic thoracolumbar fractures with incomplete neurological deficit using a retroperitoneal approach. J Bone Joint Surg Am 67:89–104PubMed McAfee PC, Bohlman HH, Yuan HA (1985) Anterior decompression of traumatic thoracolumbar fractures with incomplete neurological deficit using a retroperitoneal approach. J Bone Joint Surg Am 67:89–104PubMed
27.
Zurück zum Zitat Nystrom B, Berglund JE (1988) Spinal cord restitution following compression injuries in rats. Acta Neurol Scand 78:467–472PubMed Nystrom B, Berglund JE (1988) Spinal cord restitution following compression injuries in rats. Acta Neurol Scand 78:467–472PubMed
28.
Zurück zum Zitat Wagner FC Jr, Chehrazi B (1982) Early decompression and neurological outcome in acute cervical spinal cord injuries. J Neurosurg 56:699–705PubMed Wagner FC Jr, Chehrazi B (1982) Early decompression and neurological outcome in acute cervical spinal cord injuries. J Neurosurg 56:699–705PubMed
29.
Zurück zum Zitat Wiberg J, Hauge HN (1988) Neurological outcome after surgery for thoracic and lumbar spine injuries. Acta Neurochir (Wien) 91:106–112CrossRef Wiberg J, Hauge HN (1988) Neurological outcome after surgery for thoracic and lumbar spine injuries. Acta Neurochir (Wien) 91:106–112CrossRef
30.
Zurück zum Zitat Hadley MN, Fitzpatrick BC, Sonntag VK, Browner CM (1992) Facet fracture-dislocation injuries of the cervical spine. Neurosurgery 30:661–666PubMedCrossRef Hadley MN, Fitzpatrick BC, Sonntag VK, Browner CM (1992) Facet fracture-dislocation injuries of the cervical spine. Neurosurgery 30:661–666PubMedCrossRef
31.
Zurück zum Zitat Wolf A, Levi L, Mirvis S, Ragheb J, Huhn S, Rigamonti D et al (1991) Operative management of bilateral facet dislocation. J Neurosurg 75:883–890PubMed Wolf A, Levi L, Mirvis S, Ragheb J, Huhn S, Rigamonti D et al (1991) Operative management of bilateral facet dislocation. J Neurosurg 75:883–890PubMed
32.
Zurück zum Zitat Dai LY, Wang XY, Jiang LS (2007) Neurologic recovery from thoracolumbar burst fractures: is it predicted by the amount of initial canal encroachment and kyphotic deformity? Surg Neurol 67:232–238PubMedCrossRef Dai LY, Wang XY, Jiang LS (2007) Neurologic recovery from thoracolumbar burst fractures: is it predicted by the amount of initial canal encroachment and kyphotic deformity? Surg Neurol 67:232–238PubMedCrossRef
33.
Zurück zum Zitat Clohisy JC, Akbarnia BA, Bucholz RD, Burkus JK, Backer RJ (1992) Neurologic recovery associated with anterior decompression of spine fractures at the thoracolumbar junction (T1 2–L1). Spine 17:325–330CrossRef Clohisy JC, Akbarnia BA, Bucholz RD, Burkus JK, Backer RJ (1992) Neurologic recovery associated with anterior decompression of spine fractures at the thoracolumbar junction (T1 2–L1). Spine 17:325–330CrossRef
Metadaten
Titel
Timing of thoracolomber spine stabilization in trauma patients; impact on neurological outcome and clinical course. A real prospective (rct) randomized controlled study
verfasst von
Şahika Liva Cengiz
Erdal Kalkan
Aysegul Bayir
Kemal Ilik
Alper Basefer
Publikationsdatum
01.09.2008
Verlag
Springer-Verlag
Erschienen in
Archives of Orthopaedic and Trauma Surgery / Ausgabe 9/2008
Print ISSN: 0936-8051
Elektronische ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-007-0518-1

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