Skip to main content
Erschienen in: Archives of Orthopaedic and Trauma Surgery 11/2013

01.11.2013 | Hip Arthroplasty

Periarticular infiltration for pain relief after total hip arthroplasty: a comparison with epidural and PCA analgesia

verfasst von: Ageliki Pandazi, Ilias Kanellopoulos, Konstantinos Kalimeris, Chrysanthi Batistaki, Nikolaos Nikolakopoulos, Paraskevi Matsota, George C. Babis, Georgia Kostopanagiotou

Erschienen in: Archives of Orthopaedic and Trauma Surgery | Ausgabe 11/2013

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Epidural and intravenous patient-controlled analgesia (PCA) are established methods for pain relief after total hip arthroplasty (THA). Periarticular infiltration is an alternative method that is gaining ground due to its simplicity and safety. Our study aims to assess the efficacy of periarticular infiltration in pain relief after THA.

Methods

Sixty-three patients undergoing THA under spinal anaesthesia were randomly assigned to receive postoperative analgesia with continuous epidural infusion with ropivacaine (epidural group), intraoperative periarticular infiltration with ropivacaine, clonidine, morphine, epinephrine and corticosteroids (infiltration group) or PCA with morphine (PCA group). PCA morphine provided rescue analgesia in all groups. We recorded morphine consumption, visual analog scale (VAS) scores at rest and movement, blood loss from wound drainage, mean arterial pressure (MAP) and adverse effects at 1, 6, 12, 24 h postoperatively.

Results

Morphine consumption at all time points, VAS scores at rest, 6, 12 and 24 h and at movement, 6 and 12 h postoperatively were lower in infiltration group compared to PCA group (p < 0.05), but did not differ between infiltration and epidural group. There was no difference in adverse events in all groups. At 24 h, MAP was higher in the PCA group (p < 0.05) and blood loss was lower in the infiltration group (p < 0.05).

Conclusions

In our study periarticular infiltration was clearly superior to PCA with morphine after THA, providing better pain relief and lower opioid consumption postoperatively. Infiltration seems to be equally effective to epidural analgesia without having the potential side effects of the latter.
Literatur
1.
Zurück zum Zitat Skinner HB (2004) Multimodal acute pain management. Am J Orthop (Belle Mead NJ) 33(5 Suppl):5–9 Skinner HB (2004) Multimodal acute pain management. Am J Orthop (Belle Mead NJ) 33(5 Suppl):5–9
2.
Zurück zum Zitat Strassels SA, Chen C, Carr DB (2002) Postoperative analgesia: economics, resource use, and patient satisfaction in an urban teaching hospital. Anesth Analg 94:130–137PubMed Strassels SA, Chen C, Carr DB (2002) Postoperative analgesia: economics, resource use, and patient satisfaction in an urban teaching hospital. Anesth Analg 94:130–137PubMed
3.
Zurück zum Zitat Frater RA, Moores MA, Parry P, Hanning CD (1989) Analgesia-induced respiratory depression: comparison of meptazinol and morphine in the postoperative period. Br J Anaesth 63:260–265PubMedCrossRef Frater RA, Moores MA, Parry P, Hanning CD (1989) Analgesia-induced respiratory depression: comparison of meptazinol and morphine in the postoperative period. Br J Anaesth 63:260–265PubMedCrossRef
4.
Zurück zum Zitat Tang R, Evans H, Chaput A, Klim C (2009) Multimodal analgesia for hip arthroplasty. Orthop Clin North Am 40:377–387PubMedCrossRef Tang R, Evans H, Chaput A, Klim C (2009) Multimodal analgesia for hip arthroplasty. Orthop Clin North Am 40:377–387PubMedCrossRef
5.
Zurück zum Zitat Newsome LT, Weller RS, Gerancher JC, Kutcher MA, Royster RL (2008) Coronary artery stents: II. Perioperative considerations and management. Anesth Analg 107:570–590PubMedCrossRef Newsome LT, Weller RS, Gerancher JC, Kutcher MA, Royster RL (2008) Coronary artery stents: II. Perioperative considerations and management. Anesth Analg 107:570–590PubMedCrossRef
6.
Zurück zum Zitat Hebl JR, Kopp SL, Ali MH, Horlocker TT, Dilger JA, Lennon RL et al (2005) A comprehensive anesthesia protocol that emphasizes peripheral nerve blockade for total knee and total hip arthroplasty. J Bone Joint Surg Am 87(Suppl 2):63–70PubMedCrossRef Hebl JR, Kopp SL, Ali MH, Horlocker TT, Dilger JA, Lennon RL et al (2005) A comprehensive anesthesia protocol that emphasizes peripheral nerve blockade for total knee and total hip arthroplasty. J Bone Joint Surg Am 87(Suppl 2):63–70PubMedCrossRef
7.
Zurück zum Zitat Essving P, Axelsson K, Kjellberg J, Wallgren O, Gupta A, Lundin A (2009) Reduced hospital stay, morphine consumption, and pain intensity with local infiltration analgesia after unicompartmental knee arthroplasty. Acta Orthop 80:213–219PubMedCrossRef Essving P, Axelsson K, Kjellberg J, Wallgren O, Gupta A, Lundin A (2009) Reduced hospital stay, morphine consumption, and pain intensity with local infiltration analgesia after unicompartmental knee arthroplasty. Acta Orthop 80:213–219PubMedCrossRef
8.
Zurück zum Zitat Kerr DR, Kohan L (2008) Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients. Acta Orthop 79:174–183PubMedCrossRef Kerr DR, Kohan L (2008) Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients. Acta Orthop 79:174–183PubMedCrossRef
9.
Zurück zum Zitat Busch CA, Whitehouse MR, Shore BJ, MacDonald SJ, McCalden RW, Bourne RB (2010) The efficacy of periarticular multimodal drug infiltration in total hip arthroplasty. Clin Orthop Relat Res 468:2152–2159PubMedCrossRef Busch CA, Whitehouse MR, Shore BJ, MacDonald SJ, McCalden RW, Bourne RB (2010) The efficacy of periarticular multimodal drug infiltration in total hip arthroplasty. Clin Orthop Relat Res 468:2152–2159PubMedCrossRef
10.
Zurück zum Zitat Parvataneni HK, Ranawat AS, Ranawat CS (2007) The use of local periarticular injections in the management of postoperative pain after total hip and knee replacement: a multimodal approach. Instr Course Lect 56:125–131PubMed Parvataneni HK, Ranawat AS, Ranawat CS (2007) The use of local periarticular injections in the management of postoperative pain after total hip and knee replacement: a multimodal approach. Instr Course Lect 56:125–131PubMed
11.
Zurück zum Zitat Kardash KJ, Sarrazin F, Tessler MJ, Velly AM (2008) Single-dose dexamethasone reduces dynamic pain after total hip arthroplasty. Anesth Analg 106:1253–1257PubMedCrossRef Kardash KJ, Sarrazin F, Tessler MJ, Velly AM (2008) Single-dose dexamethasone reduces dynamic pain after total hip arthroplasty. Anesth Analg 106:1253–1257PubMedCrossRef
12.
Zurück zum Zitat Pratap JN, Shankar RK, Goroszeniuk T (2007) Co-injection of clonidine prolongs the anesthetic effect of lidocaine skin infiltration by a peripheral action. Anesth Analg 104:982–983PubMedCrossRef Pratap JN, Shankar RK, Goroszeniuk T (2007) Co-injection of clonidine prolongs the anesthetic effect of lidocaine skin infiltration by a peripheral action. Anesth Analg 104:982–983PubMedCrossRef
13.
Zurück zum Zitat Kampe S, Randebrock G, Kiencke P, Hünseler U, Cranfield K, König DP, Diefenbach C (2001) Comparison of continuous epidural infusion of ropivacaine and sufentanil with intravenous patient-controlled analgesia after total hip replacement. Anaesthesia 56:1189–1193PubMedCrossRef Kampe S, Randebrock G, Kiencke P, Hünseler U, Cranfield K, König DP, Diefenbach C (2001) Comparison of continuous epidural infusion of ropivacaine and sufentanil with intravenous patient-controlled analgesia after total hip replacement. Anaesthesia 56:1189–1193PubMedCrossRef
14.
Zurück zum Zitat Andersen LJ, Poulsen T, Krogh B, Nielsen T (2007) Postoperative analgesia in total hip arthroplasty: a randomized double-blinded, placebo-controlled study on peroperative and postoperative ropivacaine, ketorolac, and adrenaline wound infiltration. Acta Orthop 78:187–192PubMedCrossRef Andersen LJ, Poulsen T, Krogh B, Nielsen T (2007) Postoperative analgesia in total hip arthroplasty: a randomized double-blinded, placebo-controlled study on peroperative and postoperative ropivacaine, ketorolac, and adrenaline wound infiltration. Acta Orthop 78:187–192PubMedCrossRef
15.
Zurück zum Zitat Gupta A, Bodin L, Holmstrom B, Berggren L (2001) A systematic review of the peripheral analgesic effects of intraarticular morphine. Anesth Analg 93:761–770PubMedCrossRef Gupta A, Bodin L, Holmstrom B, Berggren L (2001) A systematic review of the peripheral analgesic effects of intraarticular morphine. Anesth Analg 93:761–770PubMedCrossRef
16.
Zurück zum Zitat Parvataneni HK, Shah VP, Howard H, Cole N, Ranawat AS, Ranawat CS (2007) Controlling pain after total hip and knee arthroplasty using a multimodal protocol with local periarticular injections: a prospective randomized study. J Arthoplasty 22(Suppl 2):33–38CrossRef Parvataneni HK, Shah VP, Howard H, Cole N, Ranawat AS, Ranawat CS (2007) Controlling pain after total hip and knee arthroplasty using a multimodal protocol with local periarticular injections: a prospective randomized study. J Arthoplasty 22(Suppl 2):33–38CrossRef
17.
Zurück zum Zitat Lunn TH, Kristensen BB, Andersen LØ, Husted H, Otte KS, Gaarn-Larsen L, Kehlet H (2011) Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial. Br J Anaesth 106:230–238PubMedCrossRef Lunn TH, Kristensen BB, Andersen LØ, Husted H, Otte KS, Gaarn-Larsen L, Kehlet H (2011) Effect of high-dose preoperative methylprednisolone on pain and recovery after total knee arthroplasty: a randomized, placebo-controlled trial. Br J Anaesth 106:230–238PubMedCrossRef
18.
Zurück zum Zitat Essving P, Axelsson K, Kjellberg J, Wallgren O, Gupta A, Lundin A (2010) Reduced morphine consumption and pain intensity with local infiltration analgesia (LIA) following total knee arthroplasty. Acta Orthop 81:354–360PubMedCrossRef Essving P, Axelsson K, Kjellberg J, Wallgren O, Gupta A, Lundin A (2010) Reduced morphine consumption and pain intensity with local infiltration analgesia (LIA) following total knee arthroplasty. Acta Orthop 81:354–360PubMedCrossRef
19.
Zurück zum Zitat Meunier A, Aspenberg P (2006) Parecoxib impairs early metaphyseal bone healing in rats. Arch Orthop Trauma Surg 126:433–436PubMedCrossRef Meunier A, Aspenberg P (2006) Parecoxib impairs early metaphyseal bone healing in rats. Arch Orthop Trauma Surg 126:433–436PubMedCrossRef
20.
Zurück zum Zitat McCartney CJ, Duggan E, Apatu E (2007) Should we add clonidine to local anesthetic for peripheral nerve blockade? A qualitative systematic review of the literature. Reg Anesth Pain Med 32:330–338PubMed McCartney CJ, Duggan E, Apatu E (2007) Should we add clonidine to local anesthetic for peripheral nerve blockade? A qualitative systematic review of the literature. Reg Anesth Pain Med 32:330–338PubMed
21.
Zurück zum Zitat Casati A, Magistris L, Fanelli G, Beccaria P, Cappelleri G, Aldegheri G, Torri G (2000) Small-dose clonidine prolongs postoperative analgesia after sciatic-femoral nerve block with 0.75% ropivacaine for foot surgery. Anesth Analg 91:388–392PubMed Casati A, Magistris L, Fanelli G, Beccaria P, Cappelleri G, Aldegheri G, Torri G (2000) Small-dose clonidine prolongs postoperative analgesia after sciatic-femoral nerve block with 0.75% ropivacaine for foot surgery. Anesth Analg 91:388–392PubMed
22.
Zurück zum Zitat Brill S, Plaza M (2004) Non-narcotic adjuvants may improve the duration and quality of analgesia after knee arthroscopy: a brief review. Can J Anaesth 51:975–978PubMedCrossRef Brill S, Plaza M (2004) Non-narcotic adjuvants may improve the duration and quality of analgesia after knee arthroscopy: a brief review. Can J Anaesth 51:975–978PubMedCrossRef
23.
Zurück zum Zitat Eisenach JC, De Kock M, Klimscha W (1996) alpha(2)-adrenergic agonists for regional anesthesia. A clinical review of clonidine (1984–1995). Anesthesiology 85:655–674PubMedCrossRef Eisenach JC, De Kock M, Klimscha W (1996) alpha(2)-adrenergic agonists for regional anesthesia. A clinical review of clonidine (1984–1995). Anesthesiology 85:655–674PubMedCrossRef
24.
Zurück zum Zitat Andersen KV, Pfeiffer-Jensen M, Haraldsted V, Søballe K (2007) Reduced hospital stay and narcotic consumption, and improved mobilization with local and intraarticular infiltration after hip arthroplasty: a randomized clinical trial of an intraarticular technique versus epidural infusion in 80 patients. Acta Orthop 78:180–186PubMedCrossRef Andersen KV, Pfeiffer-Jensen M, Haraldsted V, Søballe K (2007) Reduced hospital stay and narcotic consumption, and improved mobilization with local and intraarticular infiltration after hip arthroplasty: a randomized clinical trial of an intraarticular technique versus epidural infusion in 80 patients. Acta Orthop 78:180–186PubMedCrossRef
25.
Zurück zum Zitat Padala PR, Rouholamin E, Mehta RL (2004) The role of drains and tourniquets in primary total knee replacement: a comparative study of TKR performed with drains and tourniquet versus no drains and adrenaline and saline infiltration. J Knee Surg 17:24–27PubMed Padala PR, Rouholamin E, Mehta RL (2004) The role of drains and tourniquets in primary total knee replacement: a comparative study of TKR performed with drains and tourniquet versus no drains and adrenaline and saline infiltration. J Knee Surg 17:24–27PubMed
Metadaten
Titel
Periarticular infiltration for pain relief after total hip arthroplasty: a comparison with epidural and PCA analgesia
verfasst von
Ageliki Pandazi
Ilias Kanellopoulos
Konstantinos Kalimeris
Chrysanthi Batistaki
Nikolaos Nikolakopoulos
Paraskevi Matsota
George C. Babis
Georgia Kostopanagiotou
Publikationsdatum
01.11.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Archives of Orthopaedic and Trauma Surgery / Ausgabe 11/2013
Print ISSN: 0936-8051
Elektronische ISSN: 1434-3916
DOI
https://doi.org/10.1007/s00402-013-1849-8

Weitere Artikel der Ausgabe 11/2013

Archives of Orthopaedic and Trauma Surgery 11/2013 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.