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01.07.2015 | Review

Treatment of infantile haemangiomas: recommendations of a European expert group

verfasst von: Peter H. Hoeger, John I. Harper, Eulalia Baselga, Damien Bonnet, Laurence M. Boon, Marta Ciofi Degli Atti, Maya El Hachem, Arnold P. Oranje, Agneta Troilius Rubin, Lisa Weibel, Christine Léauté-Labrèze

Erschienen in: European Journal of Pediatrics | Ausgabe 7/2015

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Abstract

With a prevalence of 2.6–4.5 %, infantile haemangiomas (IH) represent the most common tumour of infancy. While the majority of IH does not require therapy and regresses spontaneously, about 10 % of IH exhibit complications such as obstruction, ulceration or disfigurement. With the advent of oral propranolol, many conventional treatment options have become obsolete. This paper summarizes current recommendations for management of complicated IH. These recommendations have been written by an expert group after a consensus process including bibliographic review, several drafts of synthesis, meetings with quantitative voting system and redaction of an approved final manuscript.

Conclusion: Oral propranolol is the first-line agent for the treatment of complicated IH.

What is Known:

• Infantile haemangiomas (IH) are the most common tumours of infancy. Within a very short period after its discovery and long before the publication of randomized controlled trials, propranolol has become the number one agent for the treatment of complicated IH.

What is New:

• We report IH treatment recommendations of an international, interdisciplinary team of experts, based on an up-to-date review of the literature.

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Titel: Treatment of infantile haemangiomas: recommendations of a European expert group
verfasst von: Peter H. Hoeger
John I. Harper
Eulalia Baselga
Damien Bonnet
Laurence M. Boon
Marta Ciofi Degli Atti
Maya El Hachem
Arnold P. Oranje
Agneta Troilius Rubin
Lisa Weibel
Christine Léauté-Labrèze
Publikationsdatum: 01.07.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Pediatrics / Ausgabe 7/2015
Print ISSN: 0340-6199
Elektronische ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-015-2570-0

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