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01.11.2004 | Original Article

Association between exercise and quality of life in multiple myeloma cancer survivors

verfasst von: Lee W. Jones, Kerry S. Courneya, Jeffrey K. H. Vallance, Aliya B. Ladha, Michael J. Mant, Andrew R. Belch, Douglas A. Stewart, Tony Reiman

Erschienen in: Supportive Care in Cancer | Ausgabe 11/2004

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Abstract

Goals of the work

The goal of this study was to examine the association between exercise and quality of life (QOL) in multiple myeloma cancer survivors.

Patients and methods

Using a retrospective design, 156 multiple myeloma cancer survivors were mailed a questionnaire that assessed self-reported exercise behavior over three periods (prediagnosis, active treatment, and off-treatment) and QOL.

Main results

The response rate was 56% (88/156). Descriptive analyses indicated that 6.8% and 20.4% of survivors met national exercise guidelines during active and off-treatment periods, respectively. Exercise during active treatment and off-treatment were positively associated with overall QOL and all subdomains of QOL (all P<0.05) except physical wellbeing.

Conclusions

A low percentage of multiple myeloma cancer survivors are exercising regularly either during active or off-treatment periods. Survivors who report more exercise during these periods also report higher QOL. These findings suggest that a randomized controlled trial is warranted.

Anderson KC, Kyle RA, Dalton WS, Landowski T, Shain K, Jove R, et al (2000) Multiple myeloma: new insights and therapeutic approaches. Hematology (Am Soc Hematol Educ Program) 147–165

Blanchard CM, Courneya KS, Laing D (2001) Effects of acute exercise on state anxiety in breast cancer survivors. Oncol Nurs Forum 28:1617–1621PubMed

Blanchard CM, Cokkinides V, Courneya KS, Nehl EJ, Stein K, Baker F (2003) A comparison of physical activity of posttreatment breast cancer survivors and noncancer controls. Behav Med 28:140–149PubMed

Cella D (1997) The Functional Assessment of Cancer Therapy–Anemia (FACT-An) scale: a new tool for the assessment of outcomes in cancer anemia and fatigue. Semin Hematol 34:13–19

Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, Bonomi A, et al (1993) The Functional Assessment of Cancer Therapy scale: development and validation of the general measure. J Clin Oncol 11:570–579PubMed

Cohen J (1992) Statistical power in the behavioral sciences, 2nd ed. Lawrence Erlbaum, Hillsdale, NJ

Coleman EA, Coon S, Hall-Barrow J, Richards K, Gaylor D, Stewart B (2003) Feasibility of exercise during treatment for multiple myeloma. Cancer Nurs 26:410–419PubMed

Courneya KS (2003) Exercise in cancer survivors: an overview of research. Med Sci Sports Exerc 35:1846–1852PubMed

Courneya KS, Friedenreich CM (1997) Relationship between exercise during cancer treatment and current quality of life in survivors of breast cancer. J Psychosoc Oncol 5:120–127

10.

Courneya KS, Friedenreich CM (1997) Relationship between exercise pattern across the cancer experience and current quality of life in colorectal cancer survivors. J Altern Complement Med 3:215–226PubMed

11.

Courneya KS, Keats MR, Turner AR (2000) Physical exercise and quality of life in cancer patients following high dose chemotherapy and autologous bone marrow transplantation. Psychooncology 9:127–136CrossRefPubMed

12.

Courneya KS, Mackey JR, McKenzie DC (2002) Exercise for breast cancer survivors: research evidence and clinical guidelines. Physician Sportsmed 30:33–42

13.

Courneya KS, Friedenreich CM, Quinney HA, Fields ALA, Jones LW, Fairey AS (2003) A randomized trial of exercise and quality of life in colorectal cancer survivors. Eur J Cancer Care 12:347–357CrossRef

14.

Courneya KS, Mackey JR, Bell GJ, Jones LW, Field CJ, Fairey AS (2003) Randomized controlled trial of exercise training in postmenopausal breast cancer survivors: cardiopulmonary and quality of life outcomes. J Clin Oncol 21:1660–1668CrossRefPubMed

15.

Dillman DA (1983) Mail and other self-administered questionnaires. In: Rossi H, Wright JD, Andersen AB (eds) Handbook of survey research. Academic Press, Toronto, pp 359–378

16.

Dimeo F, Fetscher S, Lange W, Mertelsmann R, Keul J (1997) Effects of aerobic exercise on the physical performance and incidence of treatment-related complications after high-dose chemotherapy. Blood 90:3390–3394PubMed

17.

Dimeo FC, Tilmann MH, Bertz H, Kanz L, Mertelsmann R, Keul J (1997) Aerobic exercise in the rehabilitation of cancer patients after high dose chemotherapy and autologous peripheral stem cell transplantation. Cancer 79:1717–1722CrossRefPubMed

18.

Dimeo FC, Stieglitz RD, Novelli-Fischer U, Fetscher S, Keul J (1999) Effects of physical activity on the fatigue and psychologic status of cancer patients during chemotherapy. Cancer 85:2273–2277CrossRefPubMed

19.

Durie BG, Kyle RA, Belch A, Bensinger W, Blade J, Boccadoro M, et al (2003) Myeloma management guidelines: a consensus report from the Scientific Advisors of the International Myeloma Foundation. Hematol J 4:379–398CrossRefPubMed

20.

Godin G, Shephard RJ (1985) A simple method to assess exercise behavior in the community. Can J Appl Sport Sci 10:141–146

21.

Godin G, Jobin J, Bouillon J (1986) Assessment of leisure time exercise behavior by self-report: a concurrent validity study. Can J Public Health 77:359–362PubMed

22.

Smith A, Behrens J, Drayson M, Iggo N, Jackson B, Liddi J, et al. (2001) Diagnosis and management of multiple myeloma. Br J Haematol 115:522–540CrossRefPubMed

23.

Irwin ML, Crumley D, McTiernan A, Bernstein L, Baumgartner R, Gilliland FD, et al (2003) Physical activity levels before and after a diagnosis of breast carcinoma: the Health, Eating, Activity, and Lifestyle (HEAL) study. Cancer 97:1746–1757CrossRefPubMed

24.

Jacobs DR Jr, Ainsworth BE, Hartman TJ, Leon AS (1993) A simultaneous evaluation of 10 commonly used physical activity questionnaires. Med Sci Sports Exerc 25:81–91PubMed

25.

Jones LW, Courneya KS (2002) Exercise counseling and programming preferences of cancer survivors. Cancer Pract 10:208–215CrossRefPubMed

26.

Jones LW, Courneya KS (2002) Exercise discussions during cancer treatment consultations. Cancer Pract 10:66–74CrossRefPubMed

27.

Jones LW, Courneya KS, Fairey AS, Mackey JR (in press) Effects of an oncologist’s recommendation to exercise on self-reported exercise behavior in newly diagnosed breast cancer survivors: a single-blind, randomized controlled trial. Ann Behav Med

28.

Mock V, Dow KH, Meares CJ, Grimm PM, Dienemann JA, Haisfield-Wolfe ME, et al (1997) Effects of exercise on fatigue, physical functioning, and emotional distress during radiation therapy for breast cancer. Oncol Nurs Forum 24:991–1000PubMed

29.

Mock V, Pickett M, Ropka ME, Muscari Lin E, Stewart KJ, Rhodes VA, et al (2001) Fatigue and quality of life outcomes of exercise during cancer treatment. Cancer Pract 9:119–127CrossRefPubMed

30.

Pate RR, Pratt M, Blair SN, Haskell WL, Macera CA, Bouchard C, et al (1995) Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA 273:402–407CrossRefPubMed

31.

Radloff LS (1991) The use of the Center for Epidemiologic Studies depression scale in adolescents and young adults. J Adolesc 20:149–166

32.

Schwartz AL (2000) Daily fatigue patterns and effect of exercise in women with breast cancer. Cancer Pract 8:16–24CrossRefPubMed

33.

Schwartz AL (2000) Exercise and weight gain in breast cancer patients receiving chemotherapy. Cancer Pract 8:231–237CrossRefPubMed

34.

Segal R, Evans W, Johnson D, Smith J, Colletta S, Gayton J, et al (2001) Structured exercise improves physical functioning in women with stages I and II breast cancer: results of a randomized controlled trial. J Clin Oncol 19:657–665PubMed

35.

Segal R, Reid RD, Courneya KS, Malone SC, Parliament MB, Scott CG, et al (2003) Resistance exercise in men receiving androgen deprivation therapy for prostate cancer. J Clin Oncol 21:1653–1659CrossRefPubMed

36.

Segar ML, Katch VL, Roth RS, Garcia AW, Portner TI, Glickman SG, et al (1998) The effect of aerobic exercise on self-esteem and depressive and anxiety symptoms among breast cancer survivors. Oncol Nurs Forum 25:107–113PubMed

37.

Seidl S, Kaufmann H, Drach J (2003) New insights into the pathophysiology of multiple myeloma. Lancet Oncol 4:557–564CrossRefPubMed

38.

Tian E, Zhan F, Walker R, Rasmussen E, Ma Y, Barlogie B, et al (2003) The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma. N Engl J Med 349:2483–2494CrossRefPubMed

39.

Wyatt GK, Friedman LL, Given CW, Given BA, Beckrow KC (1999) Complementary therapy use among older cancer patients. Cancer Pract 7:136–144CrossRefPubMed

40.

Yellen SB, Cella DF, Webster K, Blendowski C, Kaplan E (1997) Measuring fatigue and other anemia-related symptoms with the Functional Assessment of Cancer Therapy (FACT) measurement system. J Pain Symptom Manage 13:63–74CrossRefPubMed

Titel: Association between exercise and quality of life in multiple myeloma cancer survivors
verfasst von: Lee W. Jones
Kerry S. Courneya
Jeffrey K. H. Vallance
Aliya B. Ladha
Michael J. Mant
Andrew R. Belch
Douglas A. Stewart
Tony Reiman
Publikationsdatum: 01.11.2004
Verlag: Springer-Verlag
Erschienen in: Supportive Care in Cancer / Ausgabe 11/2004
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-004-0668-4

Springer Medizin

Association between exercise and quality of life in multiple myeloma cancer survivors