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Erschienen in:
01.10.2008 | Original Article
Health-related quality of life 18 months after breast cancer: comparison with the general population of Queensland, Australia
Erschienen in: Supportive Care in Cancer | Ausgabe 10/2008
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Goals of work
Health-related quality of life (HRQoL) was compared between urban breast cancer survivors (BCS) and the general female population in urban Queensland, and correlates were identified.
Materials and methods
HRQoL data were collected at 6, 12, and 18 months post-diagnosis from a population-based sample of 287 women, aged 74 years or younger, diagnosed with breast cancer in 2002. The urban comparison group was drawn from a population-based survey conducted in 2004 and included 675 women aged 30–74 years with no prior history of breast cancer. The Functional Assessment of Cancer Therapy-General questionnaire was used to measure HRQoL in both groups.
Main results
Younger (<50 years) BCS reported lower HRQoL at 6 months (mean, 80.2 vs 86.8) but were comparable to the general population by 12 months post-diagnosis (mean = 87.3). In contrast, HRQoL of older (50+ years) BCS at 6 months (mean = 87.1) was comparable to their general population peers (mean = 86.0) and was clinically better 18 months post-diagnosis (mean = 91.0). Compared with the general population, physical and emotional well-being among younger BCS was impaired at 6 months post-diagnosis (mean, 24.9 vs 21.0 and 21.0 vs 18.0, respectively) and did not improve over time for emotional well-being (mean = 18.8). These results persisted after adjustment for treatment-related factors, although receiving chemotherapy was an important correlate of HRQoL among younger BCS at 6 months post-diagnosis (−14.9).
Conclusions
This study not only shows that the HRQoL of BCS improves between 6 and 18 months post-diagnosis but also suggests that emotional well-being among younger BCS may benefit from targeted intervention.