Introduction
Methods
Participants
Procedure
Instruments
Fear of cancer recurrence: severity
Fear of cancer recurrence: multidimensional aspects
Distress: cancer-specific
Distress: general
Quality of life: cancer-related
Data-analyses
Results
Sample characteristics
Age (years) | Median 67.3; range = 41–88 | |
---|---|---|
Sex: male | 40 | 53 % |
Marital status | ||
Married/partnership | 55 | 72 % |
Not in partnership | 21 | 28 % |
Children: yes | 64 | 84 % |
Educational level | ||
Primary | 03 | 04 % |
Secondary | 43 | 57 % |
Tertiary | 25 | 33 % |
Other | 05 | 07 % |
Employment status | ||
Retired | 44 | 58 % |
Employed | 20 | 26 % |
Home management | 12 | 16 % |
Unemployed/others | 15 | 20 % |
Time since surgery (years) | Median 5.1; range = 1.3–9.2 | |
Location of tumor | ||
Colon | 58 | 76 % |
Rectum | 18 | 24 % |
Stoma: yes | 13 | 17 % |
Disease stage | ||
I | 13 | 17 % |
II | 31 | 41 % |
III | 32 | 42 % |
Additional treatment | ||
Chemotherapy: yes | 24 | 32 % |
Radiotherapy: yes | 10 | 13 % |
ROC analysis
CWS cut-off | Sensitivity | Specificity | PPV | NPV |
---|---|---|---|---|
Score | (%) | (%) | (%) | (%) |
8 vs 9 | 100 | 28 | 39 | 100 |
9 vs 10 | 100 | 45 | 46 | 100 |
10 vs 11 | 96 | 61 | 54 | 97 |
11 vs 12 | 91 | 72 | 61 | 94 |
12 vs 13 | 91 | 81 | 69 | 95 |
13 vs 14 | 86 | 87 | 76 | 93 |
14 vs 15 | 73 | 89 | 76 | 88 |
15 vs 16 | 59 | 92 | 76 | 83 |
16 vs 17 | 41 | 100 | 100 | 78 |
17 vs 18 | 32 | 100 | 100 | 76 |
18 vs 19 | 27 | 100 | 100 | 75 |
20 vs 21 | 18 | 100 | 100 | 72 |
22 vs 23 | 14 | 100 | 100 | 71 |
23 vs 24 | 9 | 100 | 100 | 70 |
Reliability and measure of agreement
Reliability
Prevalence and multidimensional aspects of high FCR
Low FCR (n = 47) CWS < 14 | High FCR (n = 29) CWS ≥ 14 | ||||
---|---|---|---|---|---|
EORTC QLQ-C30 | Mean | SD | Mean | SD |
p value |
Global health/QoLc
| 77.6 | (19.1) | 56.7 | (26.7) |
p < 0.001 |
Physical functioningb
| 81.1 | (21.9) | 68.5 | (30.7) |
p = 0.052 |
Role functioningc
| 81.7 | (24.1) | 59.6 | (38.1) |
p = 0.004 |
Emotional functioningc
| 93.5 | (11.3) | 72.4 | (23.9) |
p < 0.001 |
Cognitive functioningb
| 86.5 | (18.9) | 68.6 | (25.1) |
p = 0.001 |
Social functioningc
| 93.7 | (12.7) | 62.8 | (38.7) |
p < 0.001 |
EORTC QLQ-CR38 | |||||
Body imagec
| 91.4 | (15.1) | 70.4 | (32.8) |
p < 0.001 |
Sexual functioning | 23.0 | (22.6) | 20.4 | (19.8) |
p = 0.623 |
Future perspectivec
| 88.9 | (15.9) | 56.8 | (27.4) |
p < 0.001 |
General distress | |||||
HADS total | 5.5 | (5.0) | 13.8 | (6.9) |
p < 0.001 |
Cancer-specific distress | |||||
IES total | 2.8 | (6.3) | 15.4 | (14.6) |
p = 0.001 |
Intrusion | 1.9 | (3.9) | 8.2 | (7.9) |
p = 0.001 |
Avoidance | 0.9 | (2.5) | 8.0 | (7.4) |
p < 0.001 |
FCRI | |||||
Triggers | 6.3 | (5.6) | 15.5 | (5.6) |
p < 0.001 |
Psychological distress | 1.9 | (2.0) | 7.6 | (3.5) |
p < 0.001 |
Functioning impairments | 1.1 | (2.1) | 6.9 | (5.3) |
p < 0.001 |
Insight | 0.3 | (0.7) | 2.1 | (2.2) |
p < 0.001 |
Reassurance | 1.1 | (2.0) | 2.9 | (3.1) |
p = 0.005 |