Skip to main content
Erschienen in: Journal of Gastroenterology 6/2013

01.06.2013 | Original Article—Alimentary Tract

Sexual function and patients' perceptions in inflammatory bowel disease: a case–control survey

verfasst von: Laura Marín, Míriam Mañosa, Esther Garcia-Planella, Jordi Gordillo, Yamile Zabana, Eduard Cabré, Eugeni Domènech

Erschienen in: Journal of Gastroenterology | Ausgabe 6/2013

Einloggen, um Zugang zu erhalten

Abstract

Background

Sexuality is important when assessing quality of life (QoL), which is often disturbed in inflammatory bowel disease (IBD). However, sexuality is not addressed in most QoL questionnaires.

Aims

To evaluate the prevalence and predisposing factors of sexual dysfunction among IBD patients, and their own perception.

Methods

A postal survey was conducted in IBD patients 25–65 years of age from two tertiary centres. Patients were asked to provide a control of the same gender and age without IBD. The questionnaire assessed patient perception of the impact of IBD on their sexuality, and also allowed calculation of the Erectile Function International Index or the Female Sexual Function Index.

Results

A total of 355 patients and 200 controls were available for the final analysis. Both groups were comparable except for a higher proportion of individuals who had been treated for depression among patients. Half of the female and one-third of the male patients considered that both sexual desire and satisfaction worsened after IBD diagnosis. As compared to controls, both men and women with IBD showed significantly lower scores in sexual function indexes, but a higher prevalence of sexual dysfunction was only noticed among women. Independent predictors of sexual dysfunction among IBD patients were the use of corticosteroids in women, and the use of biological agents, depression and diabetes in men.

Conclusions

Sexuality is often disturbed in IBD patients, particularly among women. Many factors seem to contribute to worsened intimacy. Sexuality should be considered when QoL is assessed in these patients.
Literatur
1.
Zurück zum Zitat Romberg-Camps MJ, Dagnelie PC, Kester AD, Hesselink-van de Kruijs MA, Cilissen M, Engels LG, et al. Influence of phenotype at diagnosis and of other potential prognostic factors on the course of inflammatory bowel disease. Am J Gastroenterol. 2009;104:371–83.PubMedCrossRef Romberg-Camps MJ, Dagnelie PC, Kester AD, Hesselink-van de Kruijs MA, Cilissen M, Engels LG, et al. Influence of phenotype at diagnosis and of other potential prognostic factors on the course of inflammatory bowel disease. Am J Gastroenterol. 2009;104:371–83.PubMedCrossRef
2.
Zurück zum Zitat Hoie O, Wolters FL, Riis L, Bernklev T, Aamodt G, Clofent J, et al. Low colectomy rates in ulcerative colitis in an unselected European cohort followed for 10 years. Gastroenterology. 2007;132:507–15.PubMedCrossRef Hoie O, Wolters FL, Riis L, Bernklev T, Aamodt G, Clofent J, et al. Low colectomy rates in ulcerative colitis in an unselected European cohort followed for 10 years. Gastroenterology. 2007;132:507–15.PubMedCrossRef
3.
Zurück zum Zitat Romberg-Camps M, Kuiper E, Schouten L, Kester A, Hesselink-van de Kruijs M, Limonard C, et al. Mortality in inflammatory bowel disease in the Netherlands 1991–2002: results of a population-based study: the IBD South-Limburg cohort. Inflamm Bowel Dis. 2010;16(8):1397–410.PubMedCrossRef Romberg-Camps M, Kuiper E, Schouten L, Kester A, Hesselink-van de Kruijs M, Limonard C, et al. Mortality in inflammatory bowel disease in the Netherlands 1991–2002: results of a population-based study: the IBD South-Limburg cohort. Inflamm Bowel Dis. 2010;16(8):1397–410.PubMedCrossRef
4.
Zurück zum Zitat Höie O, Schouten LJ, Wolters FL, Solberg IC, Riis L, Mouzas IA, et al. Ulcerative colitis: no rise in mortality in a European-wide population based cohort 10 years after diagnosis. Gut. 2007;56(4):497–503.PubMedCrossRef Höie O, Schouten LJ, Wolters FL, Solberg IC, Riis L, Mouzas IA, et al. Ulcerative colitis: no rise in mortality in a European-wide population based cohort 10 years after diagnosis. Gut. 2007;56(4):497–503.PubMedCrossRef
5.
Zurück zum Zitat Wolters FL, Russel MG, Sijbrandij J, Schouten LJ, Odes S, Riis L, et al. Crohn’s disease: increased mortality 10 years after diagnosis in a Europe-wide population based cohort. Gut. 2006;55(4):510–8.PubMedCrossRef Wolters FL, Russel MG, Sijbrandij J, Schouten LJ, Odes S, Riis L, et al. Crohn’s disease: increased mortality 10 years after diagnosis in a Europe-wide population based cohort. Gut. 2006;55(4):510–8.PubMedCrossRef
6.
Zurück zum Zitat Manninen P, Karvonen AL, Huhtala H, Rasmussen M, Salo M, Mustaniemi L, et al. Mortality in ulcerative colitis and Crohn’s disease. A population-based study in Finland. J Crohns Colitis. 2012;6(5):524–8.PubMedCrossRef Manninen P, Karvonen AL, Huhtala H, Rasmussen M, Salo M, Mustaniemi L, et al. Mortality in ulcerative colitis and Crohn’s disease. A population-based study in Finland. J Crohns Colitis. 2012;6(5):524–8.PubMedCrossRef
8.
Zurück zum Zitat Habal FM, Huang VW. Review article: a decision-making algorithm for the management of pregnancy in the inflammatory bowel disease patient. Aliment Pharmacol Ther. 2012;35(5):501–15.PubMedCrossRef Habal FM, Huang VW. Review article: a decision-making algorithm for the management of pregnancy in the inflammatory bowel disease patient. Aliment Pharmacol Ther. 2012;35(5):501–15.PubMedCrossRef
9.
Zurück zum Zitat Mountifield R, Bampton P, Prosser R, Muller K, Andrews JM. Fear and fertility in inflammatory bowel disease: a mismatch of perception and reality affects family planning decisions. Inflamm Bowel Dis. 2009;15(5):720–5.PubMedCrossRef Mountifield R, Bampton P, Prosser R, Muller K, Andrews JM. Fear and fertility in inflammatory bowel disease: a mismatch of perception and reality affects family planning decisions. Inflamm Bowel Dis. 2009;15(5):720–5.PubMedCrossRef
10.
Zurück zum Zitat Heetun ZS, Byrnes C, Neary P, O’Morain C. Review article: reproduction in the patient with inflammatory bowel disease. Aliment Pharmacol Ther. 2007;26(4):513–33.PubMedCrossRef Heetun ZS, Byrnes C, Neary P, O’Morain C. Review article: reproduction in the patient with inflammatory bowel disease. Aliment Pharmacol Ther. 2007;26(4):513–33.PubMedCrossRef
11.
Zurück zum Zitat Gazzard BG, Price HL, Libby GW, Dawson AM. The social toll of Crohn′s disease. Br Med J. 1978;2:1117–9.PubMedCrossRef Gazzard BG, Price HL, Libby GW, Dawson AM. The social toll of Crohn′s disease. Br Med J. 1978;2:1117–9.PubMedCrossRef
12.
Zurück zum Zitat Moody G, Probert CSJ, Srivastava EM, Rhodes J, Mayberry JF. Sexual dysfunction amongst women with Crohn’s disease: a hidden problem. Digestion. 1992;52:179–83.PubMedCrossRef Moody G, Probert CSJ, Srivastava EM, Rhodes J, Mayberry JF. Sexual dysfunction amongst women with Crohn’s disease: a hidden problem. Digestion. 1992;52:179–83.PubMedCrossRef
13.
Zurück zum Zitat Moody G, Mayberry JF. Perceived sexual dysfunction amongst patients with inflammatory bowel disease. Digestion. 1993;54:256–60.PubMedCrossRef Moody G, Mayberry JF. Perceived sexual dysfunction amongst patients with inflammatory bowel disease. Digestion. 1993;54:256–60.PubMedCrossRef
14.
Zurück zum Zitat Timmer A, Bauer A, Dignass A, Rogler G. Sexual function in persons with inflammatory bowel disease: a survey with matched controls. Clin Gastroenterol Hepatol. 2007;5(1):87–94.PubMedCrossRef Timmer A, Bauer A, Dignass A, Rogler G. Sexual function in persons with inflammatory bowel disease: a survey with matched controls. Clin Gastroenterol Hepatol. 2007;5(1):87–94.PubMedCrossRef
15.
Zurück zum Zitat Timmer A, Bauer A, Kemptner D, Fürst A, Rogler G. Determinants of male sexual function in inflammatory bowel disease: a survey-based cross-sectional analysis in 280 men. Inflamm Bowel Dis. 2007;13(10):1236–43.PubMedCrossRef Timmer A, Bauer A, Kemptner D, Fürst A, Rogler G. Determinants of male sexual function in inflammatory bowel disease: a survey-based cross-sectional analysis in 280 men. Inflamm Bowel Dis. 2007;13(10):1236–43.PubMedCrossRef
16.
Zurück zum Zitat Timmer A, Kemptner D, Bauer A, Takses A, Ott C, Fürst A. Determinants of female sexual function in inflammatory bowel disease: a survey based cross-sectional analysis. BMC Gastroenterol. 2008;8:45.PubMedCrossRef Timmer A, Kemptner D, Bauer A, Takses A, Ott C, Fürst A. Determinants of female sexual function in inflammatory bowel disease: a survey based cross-sectional analysis. BMC Gastroenterol. 2008;8:45.PubMedCrossRef
17.
Zurück zum Zitat Muller KR, Prosser R, Bampton P, Mountifield R, Andrews JM. Female gender and surgery impair relationships, body image, and sexuality in inflammatory bowel disease: patient perceptions. Inflamm Bowel Dis. 2010;16(4):657–63.PubMedCrossRef Muller KR, Prosser R, Bampton P, Mountifield R, Andrews JM. Female gender and surgery impair relationships, body image, and sexuality in inflammatory bowel disease: patient perceptions. Inflamm Bowel Dis. 2010;16(4):657–63.PubMedCrossRef
18.
Zurück zum Zitat Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997;49(6):822–30.PubMedCrossRef Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997;49(6):822–30.PubMedCrossRef
19.
Zurück zum Zitat Hendren SK, O’Connor BI, Liu M, Asano T, Cohen Z, Swallow CJ, et al. Prevalence of male and female sexual dysfunction is high following surgery for rectal cancer. Ann Surg. 2005;242(2):212–23.PubMedCrossRef Hendren SK, O’Connor BI, Liu M, Asano T, Cohen Z, Swallow CJ, et al. Prevalence of male and female sexual dysfunction is high following surgery for rectal cancer. Ann Surg. 2005;242(2):212–23.PubMedCrossRef
20.
Zurück zum Zitat Bengtsson J, Lindholm E, Nordgren S, Berndtsson I, Oresland T, Börjesson L. Sexual function after failed ileal pouch-anal anastomosis. J Crohns Colitis. 2011;5(5):407–14.PubMedCrossRef Bengtsson J, Lindholm E, Nordgren S, Berndtsson I, Oresland T, Börjesson L. Sexual function after failed ileal pouch-anal anastomosis. J Crohns Colitis. 2011;5(5):407–14.PubMedCrossRef
21.
Zurück zum Zitat Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, et al. The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000;26(2):191–208.PubMedCrossRef Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, et al. The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000;26(2):191–208.PubMedCrossRef
22.
Zurück zum Zitat Wiegel M, Meston C, Rosen R. The female sexual function index (FSFI): cross-validation and development of clinical cutoff scores. J Sex Marital Ther. 2005;31(1):1–20.PubMedCrossRef Wiegel M, Meston C, Rosen R. The female sexual function index (FSFI): cross-validation and development of clinical cutoff scores. J Sex Marital Ther. 2005;31(1):1–20.PubMedCrossRef
23.
Zurück zum Zitat Zegarra L, Loza C, Pérez V. Validación psicométrioca del instrumento índice internacional de función eréctil en pacientes con disfunción eréctil en Perú. Rv Peru Med Exp Salud Publica. 2011;28(3):477–83.CrossRef Zegarra L, Loza C, Pérez V. Validación psicométrioca del instrumento índice internacional de función eréctil en pacientes con disfunción eréctil en Perú. Rv Peru Med Exp Salud Publica. 2011;28(3):477–83.CrossRef
24.
Zurück zum Zitat Blümel JE, Binfa L, Cataldo P, Carrasco A, Izaguirre H, Sarrá S. Indice de función sexual femenina: un test para evaluar la sexualidad de la mujer. Rev Chil Obstet Ginecol. 2004;69(2):118–25.CrossRef Blümel JE, Binfa L, Cataldo P, Carrasco A, Izaguirre H, Sarrá S. Indice de función sexual femenina: un test para evaluar la sexualidad de la mujer. Rev Chil Obstet Ginecol. 2004;69(2):118–25.CrossRef
25.
Zurück zum Zitat Bernal I, Domènech E, Garcia-Planella E, Marín L, Mañosa M, Navarro M, et al. Medication-taking behaviour in a cohort of patients with inflammatory bowel disease. Dig Dis Sci. 2006;51:2165–9.PubMedCrossRef Bernal I, Domènech E, Garcia-Planella E, Marín L, Mañosa M, Navarro M, et al. Medication-taking behaviour in a cohort of patients with inflammatory bowel disease. Dig Dis Sci. 2006;51:2165–9.PubMedCrossRef
26.
Zurück zum Zitat Garcia-Planella E, Marín L, Domènech E, Bernal I, Mañosa M, Zabana Y, et al. Utilización de medicinas alternativas y consumo de drogas en pacientes con enfermedad inflamatoria intestinal. Med Clin (Barc). 2007;128:45–8.CrossRef Garcia-Planella E, Marín L, Domènech E, Bernal I, Mañosa M, Zabana Y, et al. Utilización de medicinas alternativas y consumo de drogas en pacientes con enfermedad inflamatoria intestinal. Med Clin (Barc). 2007;128:45–8.CrossRef
27.
Zurück zum Zitat Navarro M, Mañosa M, Marín L, Domènech E, García-Castellanos R, Carrión S, et al. Fertility in patients with inflammatory bowel disease. J Crohns Colitis. 2008;2:75. Navarro M, Mañosa M, Marín L, Domènech E, García-Castellanos R, Carrión S, et al. Fertility in patients with inflammatory bowel disease. J Crohns Colitis. 2008;2:75.
28.
Zurück zum Zitat Römkens TE, Van Vugt-van Pinxteren MW, Nagengast FM, van Oijen MG, de Jong DJ. A high prevalence of fatigue in inflammatory bowel disease: case control study. J Crohns Colitis. 2011;5(4):332–7.PubMedCrossRef Römkens TE, Van Vugt-van Pinxteren MW, Nagengast FM, van Oijen MG, de Jong DJ. A high prevalence of fatigue in inflammatory bowel disease: case control study. J Crohns Colitis. 2011;5(4):332–7.PubMedCrossRef
29.
Zurück zum Zitat Graff LA, Vincent N, Walker JR, Clara I, Carr R, Ediger J, Miller N, et al. A population-based study of fatigue and sleep difficulties in inflammatory bowel disease. Inflamm Bowel Dis. 2011;17(9):1882–9.PubMedCrossRef Graff LA, Vincent N, Walker JR, Clara I, Carr R, Ediger J, Miller N, et al. A population-based study of fatigue and sleep difficulties in inflammatory bowel disease. Inflamm Bowel Dis. 2011;17(9):1882–9.PubMedCrossRef
30.
Zurück zum Zitat Bager P, Befrits R, Wikman O, Lindgren S, Moum B, Hjortswang H, et al. Fatigue in out-patients with inflammatory bowel disease is common and multifactorial. Aliment Pharmacol Ther. 2012;35(1):133–41.PubMedCrossRef Bager P, Befrits R, Wikman O, Lindgren S, Moum B, Hjortswang H, et al. Fatigue in out-patients with inflammatory bowel disease is common and multifactorial. Aliment Pharmacol Ther. 2012;35(1):133–41.PubMedCrossRef
31.
Zurück zum Zitat Jelsness-Jørgensen LP, Bernklev T, Henriksen M, Torp R, Moum B. Chronic fatigue is associated with increased disease-related worries and concerns in inflammatory bowel disease. World J Gastroenterol. 2012;18(5):445–52.PubMedCrossRef Jelsness-Jørgensen LP, Bernklev T, Henriksen M, Torp R, Moum B. Chronic fatigue is associated with increased disease-related worries and concerns in inflammatory bowel disease. World J Gastroenterol. 2012;18(5):445–52.PubMedCrossRef
32.
Zurück zum Zitat McCulloch DK, Campbell IW, Wu FC, Prescott RJ, Clarke BF. The prevalence of diabetic impotence. Diabetologia. 1980;18(4):279–83.PubMedCrossRef McCulloch DK, Campbell IW, Wu FC, Prescott RJ, Clarke BF. The prevalence of diabetic impotence. Diabetologia. 1980;18(4):279–83.PubMedCrossRef
33.
Zurück zum Zitat Perelman MA. Erectile dysfunction and depression: screening and treatment. Urol Clin North Am. 2011;38(2):125–39.PubMedCrossRef Perelman MA. Erectile dysfunction and depression: screening and treatment. Urol Clin North Am. 2011;38(2):125–39.PubMedCrossRef
Metadaten
Titel
Sexual function and patients' perceptions in inflammatory bowel disease: a case–control survey
verfasst von
Laura Marín
Míriam Mañosa
Esther Garcia-Planella
Jordi Gordillo
Yamile Zabana
Eduard Cabré
Eugeni Domènech
Publikationsdatum
01.06.2013
Verlag
Springer Japan
Erschienen in
Journal of Gastroenterology / Ausgabe 6/2013
Print ISSN: 0944-1174
Elektronische ISSN: 1435-5922
DOI
https://doi.org/10.1007/s00535-012-0700-2

Weitere Artikel der Ausgabe 6/2013

Journal of Gastroenterology 6/2013 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.