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European Spine Journal

Erschienen in:

01.08.2006 | Original Article

Altered cerebral blood flow in chronic neck pain patients but not in whiplash patients: a ^99mTc-HMPAO rCBF study

verfasst von: Torbjörn Sundström, Michel Guez, Christer Hildingsson, Göran Toolanen, Lars Nyberg, Katrine Riklund

Erschienen in: European Spine Journal | Ausgabe 8/2006

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Abstract

A cross-sectional study to investigate regional cerebral blood flow (rCBF) in patients with chronic whiplash syndrome and chronic neck pain patients without previous history of trauma along with a healthy control group. Chronic neck pain is a common disorder and a history of cervical spine injury including whiplash trauma constitute a risk factor for persistent neck pain. The aetiology of the late whiplash syndrome is unknown with no specific diagnostic criteria based on imaging, physiological, or psychological examination. Earlier studies indicate a parieto-occipital hypoperfusion but it is unclear if the hypoperfusion represents a response to chronic pain. The rCBF was monitored in 45 patients with chronic neck pain: 27 cases with chronic whiplash syndrome and 18 age and gender matched cases with non-traumatic chronic neck pain. The rCBF was estimated with single-photon emission computed tomography (SPECT) using technetium-99m hexamethylpropylene amine oxime (HMPAO). The non-traumatic patients displayed rCBF changes in comparison with the whiplash group and the healthy control group. These changes included rCBF decreases in a right temporal region close to hippocampus, and increased rCBF in left insula. The whiplash group displayed no significant differences in rCBF in comparison with the healthy controls. The present study suggests different pain mechanisms in patients with chronic neck pain of non-traumatic origin compared to those with chronic neck pain due to a whiplash trauma.

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Titel: Altered cerebral blood flow in chronic neck pain patients but not in whiplash patients: a 99mTc-HMPAO rCBF study
verfasst von: Torbjörn Sundström
Michel Guez
Christer Hildingsson
Göran Toolanen
Lars Nyberg
Katrine Riklund
Publikationsdatum: 01.08.2006
Verlag: Springer-Verlag
Erschienen in: European Spine Journal / Ausgabe 8/2006
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI: https://doi.org/10.1007/s00586-005-0040-5

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