Skip to main content
Erschienen in: European Spine Journal 2/2010

01.02.2010 | Review Article

Review of metastatic spine tumour classification and indications for surgery: the consensus statement of the Global Spine Tumour Study Group

verfasst von: David Choi, A. Crockard, C. Bunger, J. Harms, N. Kawahara, C. Mazel, R. Melcher, K. Tomita

Erschienen in: European Spine Journal | Ausgabe 2/2010

Einloggen, um Zugang zu erhalten

Abstract

Choosing the right operation for metastatic spinal tumours is often difficult, and depends on many factors, including life expectancy and the balance of the risk of surgery against the likelihood of improving quality of life. Several prognostic scores have been devised to help the clinician decide the most appropriate course of action, but there still remains controversy over how to choose the best option; more often the decision is influenced by habit, belief and subjective experience. The purpose of this article is to review the present systems available for classifying spinal metastases, how these classifications can be used to help surgical planning, discuss surgical outcomes, and make suggestions for future research. It is important for spinal surgeons to reach a consensus regarding the classification of spinal metastases and surgical strategies. The authors of this article constitute the Global Spine Tumour Study Group: an international group of spinal surgeons who are dedicated to studying the techniques and outcomes of surgery for spinal tumours, to build on the existing evidence base for the surgical treatment of spinal tumours.
Literatur
1.
Zurück zum Zitat Hatrick NC, Lucas JD, Timothy AR et al (2000) The surgical treatment of metastatic disease of the spine. Radiother Oncol 56:335–339CrossRefPubMed Hatrick NC, Lucas JD, Timothy AR et al (2000) The surgical treatment of metastatic disease of the spine. Radiother Oncol 56:335–339CrossRefPubMed
2.
Zurück zum Zitat Bailar JC III, Gornik HL (1997) Cancer undefeated. N Eng J Med 336:1569–1574CrossRef Bailar JC III, Gornik HL (1997) Cancer undefeated. N Eng J Med 336:1569–1574CrossRef
3.
Zurück zum Zitat Jacobs WB, Perrin RG (2001) Evaluation and treatment of spinal metastases: an overview. Neurosurg Focus 11 (article 10) Jacobs WB, Perrin RG (2001) Evaluation and treatment of spinal metastases: an overview. Neurosurg Focus 11 (article 10)
4.
Zurück zum Zitat Ibrahim AG, Crockard HA, Antonetti P et al (2005) Does spinal surgery improve the quality of life for those with extradural (spinal) osseous metastases? An international multi-centre prospective observational study of 223 patients. J Neurosurg Spine 8:271–278CrossRef Ibrahim AG, Crockard HA, Antonetti P et al (2005) Does spinal surgery improve the quality of life for those with extradural (spinal) osseous metastases? An international multi-centre prospective observational study of 223 patients. J Neurosurg Spine 8:271–278CrossRef
6.
Zurück zum Zitat Sakaura H, Hosono N, Mukai Y et al (2004) Outcome of total en bloc spondylectomy for solitary metastasis of the thoracolumbar spine. J Spinal Disord Tech 17:297–300CrossRefPubMed Sakaura H, Hosono N, Mukai Y et al (2004) Outcome of total en bloc spondylectomy for solitary metastasis of the thoracolumbar spine. J Spinal Disord Tech 17:297–300CrossRefPubMed
7.
Zurück zum Zitat Tomita K, Kawahara N, Kobayashi T et al (2001) Surgical strategy for spinal metastases. Spine 26:298–306CrossRefPubMed Tomita K, Kawahara N, Kobayashi T et al (2001) Surgical strategy for spinal metastases. Spine 26:298–306CrossRefPubMed
9.
Zurück zum Zitat North RB, LaRocca VR, Schwartz J et al (2005) Surgical management of spinal metastases: analysis of prognostic factors during 10-year experience. J Neurosurg Spine 2:564–573CrossRefPubMed North RB, LaRocca VR, Schwartz J et al (2005) Surgical management of spinal metastases: analysis of prognostic factors during 10-year experience. J Neurosurg Spine 2:564–573CrossRefPubMed
10.
Zurück zum Zitat Tokuhashi Y, Matsuzaki H, Oda H et al (2005) A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine 30:2186–2191CrossRefPubMed Tokuhashi Y, Matsuzaki H, Oda H et al (2005) A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis. Spine 30:2186–2191CrossRefPubMed
11.
Zurück zum Zitat Findlay GF (1984) Adverse effects of the management of malignant spinal cord compression. J Neurol Neurosurg Psychiatry 47:761–768CrossRefPubMed Findlay GF (1984) Adverse effects of the management of malignant spinal cord compression. J Neurol Neurosurg Psychiatry 47:761–768CrossRefPubMed
12.
Zurück zum Zitat Steinmetz MP, Mekhail A, Benzel EC (2001) Management of metastatic tumors of the spine: strategies and operative indications. Neurosurg Focus 11(6):e2CrossRefPubMed Steinmetz MP, Mekhail A, Benzel EC (2001) Management of metastatic tumors of the spine: strategies and operative indications. Neurosurg Focus 11(6):e2CrossRefPubMed
13.
Zurück zum Zitat Weigel B, Maghsudi M, Neumann C et al (1999) Surgical management of symptomatic spinal metastases. Post-operative outcome and quality of life. Spine 24:2240–2246CrossRefPubMed Weigel B, Maghsudi M, Neumann C et al (1999) Surgical management of symptomatic spinal metastases. Post-operative outcome and quality of life. Spine 24:2240–2246CrossRefPubMed
14.
Zurück zum Zitat Young RF, Post EM, King GA (1980) Treatment of spinal epidural metastases. Randomized prospective comparison of laminectomy and radiotherapy. J Neurosurg 53:741–748CrossRefPubMed Young RF, Post EM, King GA (1980) Treatment of spinal epidural metastases. Randomized prospective comparison of laminectomy and radiotherapy. J Neurosurg 53:741–748CrossRefPubMed
15.
Zurück zum Zitat Patchell RA, Tibbs PA, Regine WF et al (2005) Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet 366:643–648CrossRefPubMed Patchell RA, Tibbs PA, Regine WF et al (2005) Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet 366:643–648CrossRefPubMed
16.
Zurück zum Zitat Wai EK, Finkelstein JA, Tangente RP et al (2003) Quality of life in surgical treatment of metastatic spine disease. Spine 28:508–512CrossRefPubMed Wai EK, Finkelstein JA, Tangente RP et al (2003) Quality of life in surgical treatment of metastatic spine disease. Spine 28:508–512CrossRefPubMed
17.
Zurück zum Zitat Wise JJ, Fischgrund JS, Herkowitz HN et al (1999) Complication, survival rates, and risk factors of surgery for metastatic disease of the spine. Spine 24:1943–1951CrossRefPubMed Wise JJ, Fischgrund JS, Herkowitz HN et al (1999) Complication, survival rates, and risk factors of surgery for metastatic disease of the spine. Spine 24:1943–1951CrossRefPubMed
18.
Zurück zum Zitat Cooper PR, Errico TJ, Martin R et al (1993) A systematic approach to spinal reconstruction after anterior decompression for neoplastic disease of the thoracic and lumbar spine. Neurosurgery 32:1–8CrossRefPubMed Cooper PR, Errico TJ, Martin R et al (1993) A systematic approach to spinal reconstruction after anterior decompression for neoplastic disease of the thoracic and lumbar spine. Neurosurgery 32:1–8CrossRefPubMed
19.
Zurück zum Zitat Gokaslan ZL, York JE, Walsh GL et al (1998) Transthoracic vertebrectomy for metastatic spinal tumours. J Neurosurg 89:599–609CrossRefPubMed Gokaslan ZL, York JE, Walsh GL et al (1998) Transthoracic vertebrectomy for metastatic spinal tumours. J Neurosurg 89:599–609CrossRefPubMed
20.
Zurück zum Zitat Sundaresan N, Digiacinto GV, Hughes JE et al (1991) Treatment of neoplastic spinal cord compression: results of a prospective study. Neurosurgery 29:645–650CrossRefPubMed Sundaresan N, Digiacinto GV, Hughes JE et al (1991) Treatment of neoplastic spinal cord compression: results of a prospective study. Neurosurgery 29:645–650CrossRefPubMed
21.
Zurück zum Zitat Mazel C, Balabaud L, Bennis S et al (2009) Cervical and thoracic spine tumor management: surgical indications, techniques, and outcomes. Orthop Clin N Am 40:75–92CrossRef Mazel C, Balabaud L, Bennis S et al (2009) Cervical and thoracic spine tumor management: surgical indications, techniques, and outcomes. Orthop Clin N Am 40:75–92CrossRef
22.
Zurück zum Zitat National Collaborating Centre for Cancer (2008) Metastatic spinal cord compression. Diagnosis and management of adults at risk of and with metastatic spinal cord compression. NICE Guidelines CG75, TJ International Ltd, Cardiff, UK National Collaborating Centre for Cancer (2008) Metastatic spinal cord compression. Diagnosis and management of adults at risk of and with metastatic spinal cord compression. NICE Guidelines CG75, TJ International Ltd, Cardiff, UK
23.
Zurück zum Zitat Tokuhashi Y, Matsuzaki H, Toriyama S et al (1990) Scoring system for the preoperative evaluation of metastatic spine tumor prognosis. Spine 15:1110–1113CrossRefPubMed Tokuhashi Y, Matsuzaki H, Toriyama S et al (1990) Scoring system for the preoperative evaluation of metastatic spine tumor prognosis. Spine 15:1110–1113CrossRefPubMed
24.
Zurück zum Zitat Hirabayashi H, Ebara S, Kinoshita T et al (2003) Clinical outcome and survival after palliative surgery for spinal metastases. Cancer 97:476–484CrossRefPubMed Hirabayashi H, Ebara S, Kinoshita T et al (2003) Clinical outcome and survival after palliative surgery for spinal metastases. Cancer 97:476–484CrossRefPubMed
25.
Zurück zum Zitat Hosono N, Ueda T, Tamura D et al (2005) Prognostic relevance of clinical symptoms in patients with spinal metastases. Clin Orthop Relat Res 436:196–201CrossRefPubMed Hosono N, Ueda T, Tamura D et al (2005) Prognostic relevance of clinical symptoms in patients with spinal metastases. Clin Orthop Relat Res 436:196–201CrossRefPubMed
26.
Zurück zum Zitat Bartels RHMA, Feuth T, van der Maazen R et al (2007) Development of a model with which to predict the life expectancy of patients with spinal epidural metastasis. Cancer 110:2042–2049CrossRefPubMed Bartels RHMA, Feuth T, van der Maazen R et al (2007) Development of a model with which to predict the life expectancy of patients with spinal epidural metastasis. Cancer 110:2042–2049CrossRefPubMed
27.
Zurück zum Zitat Tatsui H, Onomura T, Morishita S et al (1996) Survival rates of patients with metastatic spinal cancer after scintigraphic detection of abnormal radioactive accumulation. Spine 21:2143–2148CrossRefPubMed Tatsui H, Onomura T, Morishita S et al (1996) Survival rates of patients with metastatic spinal cancer after scintigraphic detection of abnormal radioactive accumulation. Spine 21:2143–2148CrossRefPubMed
28.
Zurück zum Zitat van der Linden YM, Dijkstra SPDS, Vonk EJA et al (2005) Prediction of survival in patients with metastases in the spinal column. Cancer 103:320–328CrossRefPubMed van der Linden YM, Dijkstra SPDS, Vonk EJA et al (2005) Prediction of survival in patients with metastases in the spinal column. Cancer 103:320–328CrossRefPubMed
29.
Zurück zum Zitat Enkaoua EA, Doursounian L, Chatellier G et al (1997) Vertebral metastases: a critical appreciation of the preoperative prognostic Tokuhashi score in a series of 71 cases. Spine 22:2293–2298CrossRefPubMed Enkaoua EA, Doursounian L, Chatellier G et al (1997) Vertebral metastases: a critical appreciation of the preoperative prognostic Tokuhashi score in a series of 71 cases. Spine 22:2293–2298CrossRefPubMed
30.
Zurück zum Zitat Spiegel DA, Sampson JH, Richardson WJ et al (1995) Metastatic melanoma to the spine. Demographics, risk factors, and prognosis in 114 patients. Spine 20:2141–2146CrossRefPubMed Spiegel DA, Sampson JH, Richardson WJ et al (1995) Metastatic melanoma to the spine. Demographics, risk factors, and prognosis in 114 patients. Spine 20:2141–2146CrossRefPubMed
31.
Zurück zum Zitat Sioutos PJ, Arbit E, Meshulam CF et al (1995) Spinal metastases from solid tumors. Analysis of factors affecting survival. Cancer 76:1453–1459CrossRefPubMed Sioutos PJ, Arbit E, Meshulam CF et al (1995) Spinal metastases from solid tumors. Analysis of factors affecting survival. Cancer 76:1453–1459CrossRefPubMed
32.
Zurück zum Zitat Zeng JC, Song YM, Liu H et al (2007) The predictive value of the Tokuhashi revised scoring system for the survival time of patients with spinal metastases (Chinese). Sichan Da Xue Xue Bao Yi Xue Ban 38:488–491 Zeng JC, Song YM, Liu H et al (2007) The predictive value of the Tokuhashi revised scoring system for the survival time of patients with spinal metastases (Chinese). Sichan Da Xue Xue Bao Yi Xue Ban 38:488–491
33.
Zurück zum Zitat Zou XN, Grejs A, Li HS et al (2006) Estimation of life expectancy for selecting surgical procedure and predicting prognosis of extradural spinal metastases. Ai Zheng 25:1406–1410PubMed Zou XN, Grejs A, Li HS et al (2006) Estimation of life expectancy for selecting surgical procedure and predicting prognosis of extradural spinal metastases. Ai Zheng 25:1406–1410PubMed
34.
Zurück zum Zitat Harrington KD (1986) Metastatic disease of the spine. J Bone Joint Surg 68A:1110–1115 Harrington KD (1986) Metastatic disease of the spine. J Bone Joint Surg 68A:1110–1115
35.
Zurück zum Zitat McLain RF, Weinstein JN (1990) Tumors of the spine. Semin Spine Surg 2:157–180 McLain RF, Weinstein JN (1990) Tumors of the spine. Semin Spine Surg 2:157–180
36.
Zurück zum Zitat Enneking WF, Spainer SS, Goodman MA (1980) A system for the surgical staging of musculoskeletal sarcomas. Clin Orthop 153:106–120PubMed Enneking WF, Spainer SS, Goodman MA (1980) A system for the surgical staging of musculoskeletal sarcomas. Clin Orthop 153:106–120PubMed
37.
Zurück zum Zitat Boriani S, Weinstein JN, Biagini R (1997) Primary bone tumors of the spine: terminology and surgical staging. Spine 22:1036–1044CrossRefPubMed Boriani S, Weinstein JN, Biagini R (1997) Primary bone tumors of the spine: terminology and surgical staging. Spine 22:1036–1044CrossRefPubMed
38.
Zurück zum Zitat Ghogawala Z, Mansfield FL, Borges LF (2001) Spinal radiation before surgical decompression adversely affects outcomes of surgery for symptomatic metastatic spinal cord compression. Spine 26:818–824CrossRefPubMed Ghogawala Z, Mansfield FL, Borges LF (2001) Spinal radiation before surgical decompression adversely affects outcomes of surgery for symptomatic metastatic spinal cord compression. Spine 26:818–824CrossRefPubMed
39.
Zurück zum Zitat Falicov A, Fisher CG, Sparkes J et al (2006) Impact of surgical intervention on quality of life in patients with spinal metastases. Spine 31:2849–2856CrossRefPubMed Falicov A, Fisher CG, Sparkes J et al (2006) Impact of surgical intervention on quality of life in patients with spinal metastases. Spine 31:2849–2856CrossRefPubMed
41.
Zurück zum Zitat Choi D, Crockard HA (2009) How and why should we benchmark clinical outcomes and quality of life for surgery in spinal metastases? Br J Neurosurg 23(1):3–4CrossRefPubMed Choi D, Crockard HA (2009) How and why should we benchmark clinical outcomes and quality of life for surgery in spinal metastases? Br J Neurosurg 23(1):3–4CrossRefPubMed
42.
Zurück zum Zitat Tomita K, Kawahara N, Baba H et al (1997) Total en bloc spondylectomy: a new surgical technique for primary malignant vertebral tumors of the spine. Spine 22:324–333CrossRefPubMed Tomita K, Kawahara N, Baba H et al (1997) Total en bloc spondylectomy: a new surgical technique for primary malignant vertebral tumors of the spine. Spine 22:324–333CrossRefPubMed
43.
Zurück zum Zitat Liljenqvist U, Lerner T, Halm H, Buerger H, Gosheger G, Winkelmann W (2008) En bloc spondylectomy in malignant tumors of the spine. Eur Spine J 17(4):600–609CrossRefPubMed Liljenqvist U, Lerner T, Halm H, Buerger H, Gosheger G, Winkelmann W (2008) En bloc spondylectomy in malignant tumors of the spine. Eur Spine J 17(4):600–609CrossRefPubMed
44.
Zurück zum Zitat Oberndorfer S, Grisold W (2000) The management of malignant spinal cord compression. Spine 25:653–654CrossRefPubMed Oberndorfer S, Grisold W (2000) The management of malignant spinal cord compression. Spine 25:653–654CrossRefPubMed
Metadaten
Titel
Review of metastatic spine tumour classification and indications for surgery: the consensus statement of the Global Spine Tumour Study Group
verfasst von
David Choi
A. Crockard
C. Bunger
J. Harms
N. Kawahara
C. Mazel
R. Melcher
K. Tomita
Publikationsdatum
01.02.2010
Verlag
Springer-Verlag
Erschienen in
European Spine Journal / Ausgabe 2/2010
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-009-1252-x

Weitere Artikel der Ausgabe 2/2010

European Spine Journal 2/2010 Zur Ausgabe

Ganga Operative Spine Course

Odontoid anterior screw fixation

Intro Open Operating Theatre

Ganga Operative Spine Course

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Klinik aktuell Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Aquatherapie bei Fibromyalgie wirksamer als Trockenübungen

03.05.2024 Fibromyalgiesyndrom Nachrichten

Bewegungs-, Dehnungs- und Entspannungsübungen im Wasser lindern die Beschwerden von Patientinnen mit Fibromyalgie besser als das Üben auf trockenem Land. Das geht aus einer spanisch-brasilianischen Vergleichsstudie hervor.

Endlich: Zi zeigt, mit welchen PVS Praxen zufrieden sind

IT für Ärzte Nachrichten

Darauf haben viele Praxen gewartet: Das Zi hat eine Liste von Praxisverwaltungssystemen veröffentlicht, die von Nutzern positiv bewertet werden. Eine gute Grundlage für wechselwillige Ärztinnen und Psychotherapeuten.

Proximale Humerusfraktur: Auch 100-Jährige operieren?

01.05.2024 DCK 2024 Kongressbericht

Mit dem demographischen Wandel versorgt auch die Chirurgie immer mehr betagte Menschen. Von Entwicklungen wie Fast-Track können auch ältere Menschen profitieren und bei proximaler Humerusfraktur können selbst manche 100-Jährige noch sicher operiert werden.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.