nach oben

European Spine Journal

Erschienen in:

01.06.2013 | Ideas and Technical Innovations

Bone and joint tuberculosis

verfasst von: Carlos Pigrau-Serrallach, Dolores Rodríguez-Pardo

Erschienen in: European Spine Journal | Sonderheft 4/2013

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Bone and joint tuberculosis has increased in the past two decades in relation with AIDS epidemics.

Material and methods

A literature review of bone and joint tuberculosis, focusing on Pott’s disease.

Results

Bone and joint TB comprises a group of serious infectious diseases whose incidence has increased in the past two decades, especially in underdeveloped countries, in part due to the AIDS epidemic. Tuberculous spinal infections should be suspected in patients with an insidious, progressive history of back pain and in individuals from an endemic area, especially when the thoracic vertebrae are affected and a pattern of bone destruction with relative disc preservation and paravertebral and epidural soft tissue masses are observed. Atypical tuberculous osteoarticular manifestations involving the extraspinal skeleton, a prosthetic joint, or the trochanteric area, and nontuberculous mycobacterial infections should be considered in favorable epidemiological contexts. Surgery combined with prolonged specific antituberculous chemotherapy is mainly indicated in patients with neurological manifestations or deformities, and provides satisfactory results in most cases.

Conclusions

Spinal tuberculosis is still a relative common extra spinal manifestation of spinal tuberculosis that requires a high degree of suspicion in order to avoid neurological complications and need of surgery.

Andronikou S, Jadwat S, Douis H (2002) Patterns of disease on MRI in 53 children with tuberculous spondylitis and the role of gadolinium. Pediatr Radiol 32:798–805PubMedCrossRef

Alothmqan A, ZiadM Awada A, Al-mahmood S, Al-shadoon S, Rahman M, Khan M (2001) Tuberculous spondylitis: analysis of 69 cases from Arabia Saudi. Spine 26:E565–E570CrossRef

Babhulkar SS, Tayade WB, Babhulkar SK (1984) Atypical spinal tuberculosis. J Bone Joint Surg (Br) 66-B:239–242

Berbari EF, Hanssen AD, Duffy MC, Steckelberg JM, Osmon DR (1998) Prosthetic joint infection due to Mycobacterium tuberculosis: a case report and review of the literature. Am J Orthop 27:219–227PubMed

Biviji A, Paiement G, Steinbach L (2002) Musculoskeletal manifestations of human immunodeficiency virus infection. J Am Acad Orthop Surg 10:312–320PubMed

Brown-Elliot B (2010) Infections due to nontuberculous mycobacteria other than Mycobacterium avium intracellulare. In: En Mandell L, Bennet JE, Dolin R (eds) Principles and practice of infectious diseases, 7th edn. Churching Livingstone-Elsevier, Philadelphia, pp 3191–3198

Chastel C (2004) When the Egyptian mummies are speaking about the infections that have made them ill. Hist Sci Med 38:147–155PubMed

Colmenero JD, Morata P, Ruiz-Mesa JD, Bautista D, Bermúdez P, Bravo MJ, Queipo-Ortuño MI (2010) Multiplex real-time polymerase chain reaction. A practical approach for rapid diagnosis of tuberculous and brucellar vertebral osteomyelitis. Spine 35:E1392–E1396PubMedCrossRef

Colmenero JD, Jiménez-Mejías ME, Sánchez-Lora FJ, Palomino-Nicás J, Martos F, GarcíadelasHeras J, Pachón J (1997) Pyogenic, tuberculous, and brucellar vertebral osteomyelitis: a descriptive and comparative study of 219 cases. Ann Rheum Dis 56:709–715PubMedCrossRef

10.

Colmenero JD, Jiménez-Mejías ME, Reguera JM, Palomino-Nicás J, Ruiz-Mesa JD, Márquez-Rivas J, Lozano A, Pachón J (2004) Tuberculous vertebral osteomyelitis in the new millennium: still a diagnostic and therapeutic challenge. Eur J Clin Microbiol Infect Dis 23:477–483PubMedCrossRef

11.

Cottle L, Riordan T (2008) Infectious spondylodiscitis. J Infect 56:401–412PubMedCrossRef

12.

Crespo M, Pigrau C, Flores X, Almirante B, Falcó F, Vidal A, Pahissa A (2004) Tuberculous trochanteric bursitis: report of 5 cases and literature review. Scand J Infect Dis 36:552–558PubMedCrossRef

13.

Danchaivitr N, Temran S, Thepmongkhol K, Chiewvit P (2007) Diagnostic accuracy of MRI in tuberculous spondylitis. J Med Assoc Thail 90:1581–1589

14.

Davies P, Humpries MJ, Byfield SP, Nunn AJ, Darbyshire JH, Citron KM, Fox W (1984) Bone and Joint tuberculosis. A survey of notifications in England and Wales. J Bone Joint Surg B 66:326–330

15.

Departament de Salut (2004) Situació epidemiológica I tendencia de la endemia tuberculosa a Catalunya. Infrome annual 2004. Barcelona: department de Salut. Generalitat de Catalunya

16.

De Groote MA, Huit G (2006) Infections due to rapidly growing mycobacteria. Clin Infect Dis 42:1756–1763PubMedCrossRef

17.

Dhammi I, Jain A, Singh S, Aggarwal A, Kumar S (2003) Multifocal skeletal tuberculosis in children: a retrospective study of 18 cases. Scand J Infect Dis 35:797–799PubMedCrossRef

18.

Enache S, Plesea I, Anusca D, Zaharia B, Pop O (2005) Osteoarticular tuberculosis: a ten years case review. Rom J Morphol Embryol 46:67–72PubMed

19.

Franceschi P, Chapuis J, Curvale G, Roux H, Aquaviva P, Groulier P (1991) Trochantérites bacillaires: a propôs of 30 cases. Ver Rhum 58:433–439

20.

García-Lechuz J, Julve R, Ruiz-Serrano J, Muñoz P (2002) Espondilitis tuberculosa o enfermedad de Pott: experiencia en un hospital general. Enf Infecc Microbiol Clin 20:5–9CrossRef

21.

García-Rodríguez JF, Alvarez-Díez H, Lorenzo-García M, Mariño-Callejo L, Fernández-Rial A, Sesma-Sánchez P (2011) Extrapulmonary tuberculosis: epidemiology and risk factors. Enf Infecc Microbiol Clin 29:502–509CrossRef

22.

Gardam M, Lim S (2005) Mycobacterial osteomyelitis and arthritis. Infect Dis Clin N Am 19:819–830CrossRef

23.

Good RC, Snide DE (1982) Isolation of nontuberculous mycobacteria in the United States 1980. J Infect Dis 146:829–833PubMedCrossRef

24.

Gopal K, Raj A, Rajesh MR, Prabhu SK, Geothe J (2007) Sternal tuberculosis after sternotomy for coronary artery bypass surgery: a case report and review of the literature. J Thorac Cardiovasc Surg 133:1365–1366PubMedCrossRef

25.

Golden M, Vikram H (2005) Extrapulmonary tuberculosis: an overview. Am Fam Physician 72:1761–1768PubMed

26.

Gonzalez O, Musher D, Brar I, Furgeson S, Boktour M, Septimus EJ, Hamill RJ, Graviss EA (2003) Spectrum of bacilli Calmette-Guérin (BCG) infection after intravesical BCG immunotherapy. Clin Infect Dis 36:140–148PubMedCrossRef

27.

Griffith DE, Aksamit T, Brown-Elliot BA, Catanzaro A, Daley C, Gordin F, Holland SM, Horsburgh R, Huitt G, Lademarco MF, Iseman M, Olivier K, Ruoss S, von Reyn CF, Wallace RJ Jr, Winthrop K (2007) An official ATS/DSA statement: diagnosis, treatment and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med 175:367–416PubMedCrossRef

28.

Gunal S, Yang Z, Agarwal M, Koroglu M, Arici ZK, Durmaz R (2011) Demographic and microbial characteristics of extrapulmonary tuberculosis cases diagnosed in Malatya, Turkey, 2001–2007. BMC Public Health 11:154–161PubMedCrossRef

29.

Holland TS, Sangster MJ, Paton RW, Ormerod LP (2010) Bone and join tuberculosis in children in the Blackburn area since 2006: a case series. J Child Orthop 4:67–71PubMedCrossRef

30.

Hoing L, Wu J, Ding J, Wang X, Zheng M, Fu R, Li WB, Peng WX, He WF (2010) Multifocal skeletal tuberculosis: experience in diagnosis and treatment. Med Mal Infect 40:6–11CrossRef

31.

Houshian S, Poulsen S, Riegels-Nielsen PR (2000) Bone and joint tuberculosis in Denmark. Increase due to immigration. Acta Orthop Scand 71:312–315PubMedCrossRef

32.

Jain AK (2010) Tuberculosis of the spine. J Bone Joint Surg (Br) 92-B:905–913CrossRef

33.

Jain AK, Chauhan RS, Dhammi IK, Maheshawari AV, Ray R (2007) Tubercular pseudoaneurysm of aorta: a rare association with vertebral tuberculosis. Spine J 7:249–253PubMedCrossRef

34.

Jarzembowski JA, Young MB (2008) Nontuberculous mycobacterial infections. Arch Pathol 132:1330–1334

35.

Jutte PC, Louenhout-Royackers JH, Borgdorf MW, Horn JR (2004) Increase of bone and joint tuberculosis in the Netherlands. J Bone Joint Surg 86:901–904CrossRef

36.

Kaila R, Am Malhi, Mahmood B, Saifuddin A (2009) The incidence of multiple level non-contiguous vertebral tuberculosis detected using whole spine MRI. Eur Spine J 18:1096–1101CrossRef

37.

Kenyon P (2009) Tuberculous vertebral osteomyelitis. Findings of a 10-year review of experience in a UK centre. J Infect 59:372–373PubMedCrossRef

38.

Koya MP, Simon MA, Soloway MS (2006) Complications of intravesical therapy for urothelial cancer of the bladder. J Urol 175:2004–2010PubMedCrossRef

39.

Kumar K, Saxema MB (1988) Multiple osteoarticular tuberculosis. Int Orthop 12:135–138PubMedCrossRef

40.

Lamm DL, Meijden V, Morales APM, Brosman SA, Catalona WJ, Herr HW, Soloway MS, Steg A, Debruyne FM (1992) Incidence and treatment of complications of bacillus Calmette-Guerin intravesical therapy in superficial bladder cancer. J Urol 147:596–661PubMed

41.

Leibert E, Schluger NW, Bonk S, Rom WN (1996) Spinal tuberculosis in patients with immunodeficiency virus infection. Clinical presentation, therapy and outcome. Tuber Lung Dis 77:329–334PubMedCrossRef

42.

Lertsrisatit P, Nantiruj K, Totemchokyakam K, Janwityanujit S (2007) Extraspinal tuberculous arthritis in HIV era. Clin Rheumatol 26:319–321PubMedCrossRef

43.

Le Roux P, Quinque K, Bonnel AS, Luyer B (2005) Les atteintes extrapulmonaries de la tuberculose de l′enfant. Arch Pediatr 12:S122–S126PubMedCrossRef

44.

Luzzati R, Giacomazzi D, Danzi MC, Tacconi L, Concia E, Vento S (2009) Diagnosis, management and outcome of clinically-suspected spinal infection. J Infect 58:259–265PubMedCrossRef

45.

Mateo L, Ruiz J, Olive A, Manterola J, Pérez R, Tena X, Prats M (2007) Tuberculosis osteoarticular. Med Clin (Barc) 129:506–509CrossRef

46.

Mavrogenis AF, Sakellariou V, Tsiodras S, Papagelopulos PJ (2009) Late Mycobacterium bovis spondylitis after intravesical BCG therapy. Joint Bone Spine 76:296–300PubMedCrossRef

47.

Mulleman D, Mammou S, Griffoul I, Avimadje A, Goupille P, Vallat JP (2006) Characteristics of patients with spinal tuberculosis in a French teaching hospital. Joint Bone Spine 73:424–427PubMedCrossRef

48.

Muradali D, Gold WL, Vellend H, Becker E (1993) Multifocal osteoarticular tuberculosis: report of four cases and review of management. Clin Infect Dis 17:204–205PubMedCrossRef

49.

Mylona E, Samarkos M, Kakalou E, Fanourgiakis P, Skoutelis A (2009) Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics. Sem Arthr Rheum 39:10–17CrossRef

50.

Nikaido T, Ishibashi K, Otani K, Yabuki S, Konno S, Mori S, Ohashi K, Ishida T, Nakano M, Yamaguchi O, Suzutani T, Kikuchi S (2007) Mycobacterium bovis BCG vertebral osteomyelitis after intravesical BCG therapy, diagnosed by PCR-based genomic deletion analysis. J Clin Microbiol 45:4085–4087PubMedCrossRef

51.

Papagelopoulos P, Papadopoulos E, Mavrogenis A, Themistocleous G, Korres D, Soucacos P (2005) Tuberculous sacroiliitis. A case report and review of the literature. Eur Spine J 14:683–688PubMedCrossRef

52.

Pertuiset E, Beaudreuil J, Liote F, Horusitsky A, Kemiche F, Richette P, Clerc-Weyl D, Cerf I, Dorfmann H, Glowinski J, Crouzet J, Ziza JM, Bardin T, Meyer O, Dryll A, Kahn MF, Kuntz D (1999) Spinal tuberculosis in adults. A study of 103 cases in developed country, 1980-1994. Medicine (Baltimore) 78:309–320CrossRef

53.

Peto HM, Pratt RH, Harrington TA, Lobue PA, Armstrong LR (2009) Epidemiology of extrapulmonary tuberculosis in the United States, 1993-96. Clin Infect Dis 49:1350–1357PubMedCrossRef

54.

Pigrau C, Almirante B, Flores X, Falcó V, Rodríguez D, Gasser I, Villanueva C, Pahissa A (2005) Spontaneous pyogenic vertebral osteomyelitis and endocarditis: incidence, risk factors and outcome. Am J Med 118:1287–1292PubMedCrossRef

55.

Polley P, Dunn R (2007) Noncontiguous vertebral tuberculosis detected using whole spine MRI. J Spinal Disord Tech 20:78–81CrossRef

56.

Pring M, Eckhoff DG (1996) Mycobacterium chelonae infection following a total knee arthroplasty. J Arthroplast 11:115–116CrossRef

57.

Rajasekaran S (2001) The natural history of post-tubercular kyphosis in children: radiological signs which predict late increase in deformity. J Bone Joint Surgery (Br) 83-B:954–962CrossRef

58.

Rezai A, Lee M, Cooper P, Tomas E, Koslow M (1995) Modern management of spinal tuberculosis. Neurosurgery 36:87–97PubMedCrossRef

59.

Richter R, Nubling W, Kohler G, Iljinski A (1983) Tuberculosis of the iliosacral joints. Treatment, results, prognosis, and differential diagnosis. Z Orthop Ihre Grenzgeb 121:564–570PubMedCrossRef

60.

Rubinstein EM, Lehman T (1996) Sternal osteomyelitis due to Mycobacterium tuberculosis following coronary artery by pass surgery. Clin Infect Dis 23:202–203CrossRef

61.

Segal A, Krausse ES (2007) Infected total hip arthroplasty after intravesical bacillus Calmette-Guerin therapy. J Arthroplasty 22:759–762PubMedCrossRef

62.

Shanbhag V, Kotwal R, Gaitonde A, Singhal K (2009) Total hip replacement infected with Mycobacterium tuberculosis. A case report with review of the literature. Acta Orthop Belg 75:119–121PubMed

63.

Sharief HS, Clarc DC, Ashbed MY, Haddad MC, alDeeb SM, Yaqub B, alMoutaery KR (1990) Granulomatous spinal infections. MR imaging. Radiology 177:101–107

64.

Tayles N, Buckley HR (2004) Leprosy and tuberculosis in Iron Age Southeast Asia. Am J Phys Anthropol 125:239–256PubMedCrossRef

65.

Tuli SM (1969) Treatment of neurological complications in tuberculosis of the spine. J Bone Joint Surg (Am) 51-A:680–692

66.

Turunc T, Demiroglu Y, Uncu H, Colakoglu S, Arsian H (2007) A comparative analysis of tuberculous, brucellar and pyogenic spontaneous spondylodiscitis patients. J Infect 55:158–163PubMedCrossRef

67.

Turgut M (2001) Spinal tuberculosis (Pott’s disease): its clinical presentation, surgical management, and outcome. A survey study on 694 patients. Neurosurg Rev 24:8–13PubMedCrossRef

68.

Yoon HJ, Song YG, Park WI, Chol JP, Chanh KH, Kim JM (2004) Clinical manifestations and diagnosis of extrapulmonary tuberculosis. Yonsei Med J 45:453–461PubMed

69.

Zimmerli W (2010) Vertebral osteomyelitis. New Eng J Med 362:1022–1029PubMedCrossRef

70.

Zink A, Chass CJ, Reisch U, Szeimies U, Nerlich AG (2001) Molecular analysis of skeletal tuberculosis in an ancient Egyptian population. J Med Microbiol 50:355–566PubMed

71.

Zink AR, Grabner W, Nerlich AG (2005) Molecular identification of human tuberculosis in recent and historic bone tissue samples. The role of molecular techniques for the study of historic tuberculosis. Am J Phys Antropol 126:32–47CrossRef

72.

Weng CH, Chi CH, Shih P, Ho CH, Po Lin, Chou CH, Wang JH, Ho MW (2010) Spinal tuberculosis in non-HIV infected patients: a 10-year experience of a medical centre in central Taiwan. J Microbiol Immunol Infect 43:464–469PubMedCrossRef

Titel: Bone and joint tuberculosis
verfasst von: Carlos Pigrau-Serrallach
Dolores Rodríguez-Pardo
Publikationsdatum: 01.06.2013
Verlag: Springer-Verlag
Erschienen in: European Spine Journal / Ausgabe Sonderheft 4/2013
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI: https://doi.org/10.1007/s00586-012-2331-y

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen.
» Jetzt entdecken

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Aquatherapie bei Fibromyalgie wirksamer als Trockenübungen

03.05.2024 Fibromyalgiesyndrom Nachrichten

Bewegungs-, Dehnungs- und Entspannungsübungen im Wasser lindern die Beschwerden von Patientinnen mit Fibromyalgie besser als das Üben auf trockenem Land. Das geht aus einer spanisch-brasilianischen Vergleichsstudie hervor.

Endlich: Zi zeigt, mit welchen PVS Praxen zufrieden sind

IT für Ärzte Nachrichten

Darauf haben viele Praxen gewartet: Das Zi hat eine Liste von Praxisverwaltungssystemen veröffentlicht, die von Nutzern positiv bewertet werden. Eine gute Grundlage für wechselwillige Ärzte und Psychotherapeuten.

Proximale Humerusfraktur: Auch 100-Jährige operieren?

01.05.2024 DCK 2024 Kongressbericht

Mit dem demographischen Wandel versorgt auch die Chirurgie immer mehr betagte Menschen. Von Entwicklungen wie Fast-Track können auch ältere Menschen profitieren und bei proximaler Humerusfraktur können selbst manche 100-Jährige noch sicher operiert werden.

Sind Frauen die fähigeren Ärzte?

30.04.2024 Gendermedizin Nachrichten

Patienten, die von Ärztinnen behandelt werden, dürfen offenbar auf bessere Therapieergebnisse hoffen als Patienten von Ärzten. Besonders scheint das auf weibliche Kranke zuzutreffen, wie eine Studie zeigt.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar "Chronische Unterbauch- und Viszeralschmerzen in der Praxis managen"

Springer Medizin

Bone and joint tuberculosis

Abstract

Introduction

Material and methods

Results

Conclusions

Arthropedia

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Aquatherapie bei Fibromyalgie wirksamer als Trockenübungen

Endlich: Zi zeigt, mit welchen PVS Praxen zufrieden sind

Proximale Humerusfraktur: Auch 100-Jährige operieren?

Sind Frauen die fähigeren Ärzte?

Update Orthopädie und Unfallchirurgie

Live-Webinar "Chronische Unterbauch- und Viszeralschmerzen in der Praxis managen"

Springer Medizin

Abstract

Introduction

Material and methods

Results

Conclusions

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Sonderheft 4/2013

Natural history of Pott’s kyphosis

Historical aspects of Pott’s disease (spinal tuberculosis) management

Tuberculosis of the craniovertebral junction

Clinical and radiological outcomes after conservative treatment of TB spondylitis: is the 15 years’ follow-up in the MRC study long enough?

Tuberculosis and Pott’s disease, still very relevant health problems

Epidemiology of tuberculosis in WHO European Region and public health response

Arthropedia

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Aquatherapie bei Fibromyalgie wirksamer als Trockenübungen

Endlich: Zi zeigt, mit welchen PVS Praxen zufrieden sind

Proximale Humerusfraktur: Auch 100-Jährige operieren?

Sind Frauen die fähigeren Ärzte?

Update Orthopädie und Unfallchirurgie