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Erschienen in:
01.02.2012 | Original Article
Healing of cavitary bone defects
Erschienen in: European Journal of Orthopaedic Surgery & Traumatology | Ausgabe 2/2012
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Background
It has been a retrospective review of healing of bone defects, due to benign tumours or tumour-like lesions. We evaluated the therapeutical outcome in patients after use of either autologous bone grafts, or β-tricalcium phosphate (β-TCP), or mixture of both components. We tried to find indications for β-TCP application.
Methods
The initial volume of defects, as well as, their volume in the follow-up period resorption of the filling materials and trabeculation of the defects were measured using radiographs. By means of statistical analysis, we sought a dependence of bone healing on the initial volume of the defect, type of bone involved, patient’s age, gender and weight-bearing.
Results
During the period of 6 years from 2003 to 2009, 87 patients with bone defects (average volume 15 cm3) were included. Significant factor for bone healing remains the volume of the defect, and in case of large defects, there was a restricted progress of trabeculation into the central part.
Conclusions
Autologous bone grafts remain the gold standard in the healing of bone defects. β-TCP may be indicated in cases where there is insufficient amount of autologous bone grafts or in cases of bone defects up to 4 cm3 particularly in epiphysis or metaphysis.