Skip to main content
Erschienen in: Archives of Virology 1/2013

01.01.2013 | Brief Report

Hepatitis C virus genotype diversity in Shanghai, China

verfasst von: Shaokun Pan, Yuliang Rao, Jiangyan Li, Huijuan Yang, Jing Tang, Renqian Zhong, Jianwei Zhai, Jing Liu, Hao Wang, Wei Liu, Youhua Xie

Erschienen in: Archives of Virology | Ausgabe 1/2013

Einloggen, um Zugang zu erhalten

Abstract

We studied 67 hepatitis C virus (HCV) isolates from 64 hospitalized patients in Shanghai, China. Genotype 1 was prevalent, and genotypes 2, 3, 6 were found for the first time in Shanghai. A rare mixed infection with three subtypes (1a, 1b, 2a) was found. The complete genome sequence of a subtype 3b isolate was determined and analyzed.
Literatur
1.
Zurück zum Zitat Chayama K, Tsubota A, Koida I, Arase Y, Saitoh S, Ikeda K, Kumada H (1994) Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C. J Gen Virol 75(Pt 12):3623–3628PubMedCrossRef Chayama K, Tsubota A, Koida I, Arase Y, Saitoh S, Ikeda K, Kumada H (1994) Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C. J Gen Virol 75(Pt 12):3623–3628PubMedCrossRef
2.
Zurück zum Zitat Chen YD, Liu MY, Yu WL, Li JQ, Dai Q, Zhou ZQ, Tisminetzky SG (2003) Mix-infections with different genotypes of HCV and with HCV plus other hepatitis viruses in patients with hepatitis C in China. World J Gastroenterol 9:984–992PubMed Chen YD, Liu MY, Yu WL, Li JQ, Dai Q, Zhou ZQ, Tisminetzky SG (2003) Mix-infections with different genotypes of HCV and with HCV plus other hepatitis viruses in patients with hepatitis C in China. World J Gastroenterol 9:984–992PubMed
3.
Zurück zum Zitat Cui XH, Pan W, Qi ZT (1995) Genotyping of hepatitis C virus in patients with hepatocellular carcinoma. Zhonghua Yi Xue Za Zhi 75(92–93):126–127 Cui XH, Pan W, Qi ZT (1995) Genotyping of hepatitis C virus in patients with hepatocellular carcinoma. Zhonghua Yi Xue Za Zhi 75(92–93):126–127
4.
Zurück zum Zitat Fu Y, Wang Y, Xia W, Pybus OG, Qin W, Lu L, Nelson K (2011) New trends of HCV infection in China revealed by genetic analysis of viral sequences determined from first-time volunteer blood donors. J Viral Hepat 18:42–52PubMedCrossRef Fu Y, Wang Y, Xia W, Pybus OG, Qin W, Lu L, Nelson K (2011) New trends of HCV infection in China revealed by genetic analysis of viral sequences determined from first-time volunteer blood donors. J Viral Hepat 18:42–52PubMedCrossRef
5.
Zurück zum Zitat Hnatyszyn HJ (2005) Chronic hepatitis C and genotyping: the clinical significance of determining HCV genotypes. Antivir Ther 10:1–11PubMed Hnatyszyn HJ (2005) Chronic hepatitis C and genotyping: the clinical significance of determining HCV genotypes. Antivir Ther 10:1–11PubMed
6.
Zurück zum Zitat Hwang SJ, Lee SD, Lu RH, Chu CW, Wu JC, Lai ST, Chang FY (2001) Hepatitis C viral genotype influences the clinical outcome of patients with acute posttransfusion hepatitis C. J Med Virol 65:505–509PubMedCrossRef Hwang SJ, Lee SD, Lu RH, Chu CW, Wu JC, Lai ST, Chang FY (2001) Hepatitis C viral genotype influences the clinical outcome of patients with acute posttransfusion hepatitis C. J Med Virol 65:505–509PubMedCrossRef
7.
Zurück zum Zitat Jiang W, Gu S, Hu Y (1999) Genotyping of HCV isolates from different populations in Shanghai by using second generation line probe assay. Zhonghua Gan Zang Bing Za Zhi 7:29–30PubMed Jiang W, Gu S, Hu Y (1999) Genotyping of HCV isolates from different populations in Shanghai by using second generation line probe assay. Zhonghua Gan Zang Bing Za Zhi 7:29–30PubMed
8.
Zurück zum Zitat Kolykhalov AA, Agapov EV, Blight KJ, Mihalik K, Feinstone SM, Rice CM (1997) Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science 277:570–574PubMedCrossRef Kolykhalov AA, Agapov EV, Blight KJ, Mihalik K, Feinstone SM, Rice CM (1997) Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science 277:570–574PubMedCrossRef
9.
Zurück zum Zitat Lu L, Nakano T, He Y, Fu Y, Hagedorn CH, Robertson BH (2005) Hepatitis C virus genotype distribution in China: predominance of closely related subtype 1b isolates and existence of new genotype 6 variants. J Med Virol 75:538–549PubMedCrossRef Lu L, Nakano T, He Y, Fu Y, Hagedorn CH, Robertson BH (2005) Hepatitis C virus genotype distribution in China: predominance of closely related subtype 1b isolates and existence of new genotype 6 variants. J Med Virol 75:538–549PubMedCrossRef
10.
Zurück zum Zitat Lu L, Nakano T, Li C, Fu Y, Miller S, Kuiken C, Robertson BH, Hagedorn CH (2006) Hepatitis C virus complete genome sequences identified from China representing subtypes 6k and 6n and a novel, as yet unassigned subtype within genotype 6. J Gen Virol 87:629–634PubMedCrossRef Lu L, Nakano T, Li C, Fu Y, Miller S, Kuiken C, Robertson BH, Hagedorn CH (2006) Hepatitis C virus complete genome sequences identified from China representing subtypes 6k and 6n and a novel, as yet unassigned subtype within genotype 6. J Gen Virol 87:629–634PubMedCrossRef
11.
Zurück zum Zitat Lu L, Li C, Fu Y, Thaikruea L, Thongswat S, Maneekarn N, Apichartpiyakul C, Hotta H, Okamoto H, Netski D, Pybus OG, Murphy D, Hagedorn CH, Nelson KE (2007) Complete genomes for hepatitis C virus subtypes 6f, 6i, 6j and 6m: viral genetic diversity among Thai blood donors and infected spouses. J Gen Virol 88:1505–1518PubMedCrossRef Lu L, Li C, Fu Y, Thaikruea L, Thongswat S, Maneekarn N, Apichartpiyakul C, Hotta H, Okamoto H, Netski D, Pybus OG, Murphy D, Hagedorn CH, Nelson KE (2007) Complete genomes for hepatitis C virus subtypes 6f, 6i, 6j and 6m: viral genetic diversity among Thai blood donors and infected spouses. J Gen Virol 88:1505–1518PubMedCrossRef
12.
Zurück zum Zitat Lu L, Murphy D, Li C, Liu S, Xia X, Pham PH, Jin Y, Hagedorn CH, Abe K (2008) Complete genomes of three subtype 6t isolates and analysis of many novel hepatitis C virus variants within genotype 6. J Gen Virol 89:444–452PubMedCrossRef Lu L, Murphy D, Li C, Liu S, Xia X, Pham PH, Jin Y, Hagedorn CH, Abe K (2008) Complete genomes of three subtype 6t isolates and analysis of many novel hepatitis C virus variants within genotype 6. J Gen Virol 89:444–452PubMedCrossRef
13.
Zurück zum Zitat Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R, Goodman ZD, Koury K, Ling M, Albrecht JK (2001) Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 358:958–965PubMedCrossRef Manns MP, McHutchison JG, Gordon SC, Rustgi VK, Shiffman M, Reindollar R, Goodman ZD, Koury K, Ling M, Albrecht JK (2001) Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 358:958–965PubMedCrossRef
14.
Zurück zum Zitat Murphy DG, Willems B, Deschenes M, Hilzenrat N, Mousseau R, Sabbah S (2007) Use of sequence analysis of the NS5B region for routine genotyping of hepatitis C virus with reference to C/E1 and 5 ‘ untranslated region sequences. Journal of Clinical Microbiology 45:1102–1112PubMedCrossRef Murphy DG, Willems B, Deschenes M, Hilzenrat N, Mousseau R, Sabbah S (2007) Use of sequence analysis of the NS5B region for routine genotyping of hepatitis C virus with reference to C/E1 and 5 ‘ untranslated region sequences. Journal of Clinical Microbiology 45:1102–1112PubMedCrossRef
15.
Zurück zum Zitat Pawlotsky JM (2003) Mechanisms of antiviral treatment efficacy and failure in chronic hepatitis C. Antiviral Res 59:1–11PubMedCrossRef Pawlotsky JM (2003) Mechanisms of antiviral treatment efficacy and failure in chronic hepatitis C. Antiviral Res 59:1–11PubMedCrossRef
16.
Zurück zum Zitat Reed KE, Rice CM (2000) Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties. Curr Top Microbiol Immunol 242:55–84PubMedCrossRef Reed KE, Rice CM (2000) Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties. Curr Top Microbiol Immunol 242:55–84PubMedCrossRef
17.
Zurück zum Zitat Sandres-Saune K, Deny P, Pasquier C, Thibaut V, Duverlie G, Izopet J (2003) Determining hepatitis C genotype by analyzing the sequence of the NS5b region. J Virol Methods 109:187–193PubMedCrossRef Sandres-Saune K, Deny P, Pasquier C, Thibaut V, Duverlie G, Izopet J (2003) Determining hepatitis C genotype by analyzing the sequence of the NS5b region. J Virol Methods 109:187–193PubMedCrossRef
18.
Zurück zum Zitat Sievert W, Altraif I, Razavi HA, Abdo A, Ahmed EA, Alomair A, Amarapurkar D, Chen CH, Dou X, El Khayat H, Elshazly M, Esmat G, Guan R, Han KH, Koike K, Largen A, McCaughan G, Mogawer S, Monis A, Nawaz A, Piratvisuth T, Sanai FM, Sharara AI, Sibbel S, Sood A, Suh DJ, Wallace C, Young K, Negro F (2011) A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt. Liver Int 31(Suppl 2):61–80PubMedCrossRef Sievert W, Altraif I, Razavi HA, Abdo A, Ahmed EA, Alomair A, Amarapurkar D, Chen CH, Dou X, El Khayat H, Elshazly M, Esmat G, Guan R, Han KH, Koike K, Largen A, McCaughan G, Mogawer S, Monis A, Nawaz A, Piratvisuth T, Sanai FM, Sharara AI, Sibbel S, Sood A, Suh DJ, Wallace C, Young K, Negro F (2011) A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt. Liver Int 31(Suppl 2):61–80PubMedCrossRef
19.
Zurück zum Zitat Simmonds P, Bukh J, Combet C, Deleage G, Enomoto N, Feinstone S, Halfon P, Inchauspe G, Kuiken C, Maertens G, Mizokami M, Murphy DG, Okamoto H, Pawlotsky JM, Penin F, Sablon E, Shin IT, Stuyver LJ, Thiel HJ, Viazov S, Weiner AJ, Widell A (2005) Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. Hepatology 42:962–973PubMedCrossRef Simmonds P, Bukh J, Combet C, Deleage G, Enomoto N, Feinstone S, Halfon P, Inchauspe G, Kuiken C, Maertens G, Mizokami M, Murphy DG, Okamoto H, Pawlotsky JM, Penin F, Sablon E, Shin IT, Stuyver LJ, Thiel HJ, Viazov S, Weiner AJ, Widell A (2005) Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. Hepatology 42:962–973PubMedCrossRef
20.
Zurück zum Zitat Xu B, Lu P, Zhu M (2000) Epidemiological aspects of the genotype of hepatitis C virus. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 14:148–150PubMed Xu B, Lu P, Zhu M (2000) Epidemiological aspects of the genotype of hepatitis C virus. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 14:148–150PubMed
Metadaten
Titel
Hepatitis C virus genotype diversity in Shanghai, China
verfasst von
Shaokun Pan
Yuliang Rao
Jiangyan Li
Huijuan Yang
Jing Tang
Renqian Zhong
Jianwei Zhai
Jing Liu
Hao Wang
Wei Liu
Youhua Xie
Publikationsdatum
01.01.2013
Verlag
Springer Vienna
Erschienen in
Archives of Virology / Ausgabe 1/2013
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-012-1457-x

Weitere Artikel der Ausgabe 1/2013

Archives of Virology 1/2013 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Erhöhte Mortalität bei postpartalem Brustkrebs

07.05.2024 Mammakarzinom Nachrichten

Auch für Trägerinnen von BRCA-Varianten gilt: Erkranken sie fünf bis zehn Jahre nach der letzten Schwangerschaft an Brustkrebs, ist das Sterberisiko besonders hoch.

Hypertherme Chemotherapie bietet Chance auf Blasenerhalt

07.05.2024 Harnblasenkarzinom Nachrichten

Eine hypertherme intravesikale Chemotherapie mit Mitomycin kann für Patienten mit hochriskantem nicht muskelinvasivem Blasenkrebs eine Alternative zur radikalen Zystektomie darstellen. Kölner Urologen berichten über ihre Erfahrungen.

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Medizinstudium Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

Vorhofflimmern bei Jüngeren gefährlicher als gedacht

06.05.2024 Vorhofflimmern Nachrichten

Immer mehr jüngere Menschen leiden unter Vorhofflimmern. Betroffene unter 65 Jahren haben viele Risikofaktoren und ein signifikant erhöhtes Sterberisiko verglichen mit Gleichaltrigen ohne die Erkrankung.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.