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Clinical Oral Investigations
Erschienen in: Clinical Oral Investigations 4/2014

01.05.2014 | Original Article

A randomized clinical trial to evaluate the impact of a dental care program in the quality of life of head and neck cancer patients

verfasst von: Camila Samara Funk, Cristine Maria Warmling, Julio Baldisserotto

Erschienen in: Clinical Oral Investigations | Ausgabe 4/2014

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Abstract

Objectives

A randomized clinical trial (RCT) to evaluate the impact of dental care program on the quality of life (QOL) of head and neck cancer patients under oncological treatment.

Materials and methods

The study design was a parallel RCT where 46 subjects with a diagnosis of head and neck primary neoplasy were randomly allocated to the control (CG) or test group (TG). Both groups received basic dental care but the TG received a complimentary care before and during, oncological therapy. Data related to general (WHOQOL-BREF) and specific (EORTC QLQ H&N 35) QOL were assessed before and 15 days after the conclusion of the oncological therapy.

Results

The TG showed an improvement in the general and specific QOL, while the CG showed a worsening in these indexes but without significant difference. The variation between the initial and final measures in the TG shows a tendency of significant improvement along the time. A reduction in candidiasis (p < 0.05) and muccositis was observed in the TG.

Conclusion

In a short follow-up period, dental care was able to reduce damage from the oncological therapy especially related to muccositis and candidiasis, although the QOL was not significantly improved. However, a longer follow-up to measure the late side effects over the QOL of these patients is necessary.

Clinical relevance

Provision of continuous dental care for head and neck cancer patients can reduce deleterious side effects of the oncological treatment.
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Metadaten
Titel
A randomized clinical trial to evaluate the impact of a dental care program in the quality of life of head and neck cancer patients
verfasst von
Camila Samara Funk
Cristine Maria Warmling
Julio Baldisserotto
Publikationsdatum
01.05.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Oral Investigations / Ausgabe 4/2014
Print ISSN: 1432-6981
Elektronische ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-013-1068-2

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