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Erschienen in:
01.11.2008 | Original Paper
A prospective study of educational background and breast cancer among Japanese women
Erschienen in: Cancer Causes & Control | Ausgabe 9/2008
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Objective
This prospective cohort study examined the association between educational level and breast cancer incidence in Japan.
Method
A baseline survey was conducted between 1988 and 1990 among 110,792 residents of 45 areas, aged 40–79 years. Data were restricted to 24 areas where incidence registry data were available, and to subjects which provided information on educational level (32,646). The subjects were assigned to three groups according to their level of education (<16, 16–18, 18<). During 13 years of follow-up (328,931 person-year), 169 cases of breast cancer were newly diagnosed.
Results
Women with a high level of education had an increased risk of breast cancer (HR = 1.93, 95 percent confidence interval (95% CI): 1.18, 3.16, in women with the highest educational level) compared with women with the lowest educational level. Adjustment for lifestyle and reproductive factors did not substantially change the results. In addition, when analyses were stratified by age subgroups, the educational difference in breast cancer incidence was more evident among the younger than the elder subgroup.
Conclusion
The present results suggested that cancer prevention strategies should recognize women with a higher educational level as a high risk group for breast cancer.