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01.09.2010 | Original Paper

Pickled meat consumption and colorectal cancer (CRC): a case–control study in Newfoundland and Labrador, Canada

verfasst von: Josh Squires, Barbara Roebothan, Sharon Buehler, Zhuoyu Sun, Michelle Cotterchio, Ban Younghusband, Elizabeth Dicks, John R. Mclaughlin, Patrick S. Parfrey, Peizhong Peter Wang

Erschienen in: Cancer Causes & Control | Ausgabe 9/2010

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Abstract

Objective

Although a large body of epidemiological research suggests that red meat intake increases the risk of colorectal cancer, little is known regarding how such an association varies across populations and types of red meat. The objective of this study was to assess whether an association exists between the intakes of total red meat and pickled red meat and the risk of colorectal cancer in study subjects residing in Newfoundland and Labrador.

Methods

This case–control study of 1,204 residents of Newfoundland and Labrador was part of a larger study on colorectal cancer. Personal history food frequency questionnaires were used to collect retrospective data from 518 individuals diagnosed with colorectal cancer and 686 controls. Intakes were ranked and divided into tertiles. Logistic regression was used to examine the possible association between meat intakes and colorectal cancer diagnosis while controlling for possible confounding factors.

Results

A positive, but non-statistically significant, association between total red meat intake and CRC was observed in this study. Pickled red meat consumption was found to be significantly associated with an increased risk of CRC (men, OR = 2.07, 95% CI 1.37–3.15; women, OR = 2.51, 95% CI 1.45–4.32), the odds ratios increasing with each tertile of consumption, suggesting a dose–response effect.

Conclusion

Intake of pickled red meat appears to increase the risk of colorectal cancer in Newfoundland and Labrador.

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Titel: Pickled meat consumption and colorectal cancer (CRC): a case–control study in Newfoundland and Labrador, Canada
verfasst von: Josh Squires
Barbara Roebothan
Sharon Buehler
Zhuoyu Sun
Michelle Cotterchio
Ban Younghusband
Elizabeth Dicks
John R. Mclaughlin
Patrick S. Parfrey
Peizhong Peter Wang
Publikationsdatum: 01.09.2010
Verlag: Springer Netherlands
Erschienen in: Cancer Causes & Control / Ausgabe 9/2010
Print ISSN: 0957-5243
Elektronische ISSN: 1573-7225
DOI: https://doi.org/10.1007/s10552-010-9580-z

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Pickled meat consumption and colorectal cancer (CRC): a case–control study in Newfoundland and Labrador, Canada