Anzeige
Erschienen in:
01.01.2016 | Original paper
Obesity, ethnicity, and quality of life among breast cancer survivors and women without breast cancer: the long-term quality of life follow-up study
Erschienen in: Cancer Causes & Control | Ausgabe 1/2016
Einloggen, um Zugang zu erhaltenAbstract
Purpose
The purpose of this study was to examine the relationship between obesity and quality of life (QOL) among Hispanic and non-Hispanic white breast cancer survivors and population-based controls from the ‘Long-Term Quality of Life Study’—a 12- to 15-year follow-up study of breast cancer cases/survivors and controls from New Mexico (n = 451).
Methods
Using multiple linear regressions, obesity measures [body mass index (BMI) ≥ 30 kg/m2] at baseline and follow-up interview were modeled with composite scores for physical and mental health from the SF-36 Quality of Life Survey. Interaction between ethnicity and BMI and change in BMI were evaluated. All models were adjusted for age, ethnicity, Charlson Index, depression, fatigue, and physical activity.
Results
Baseline obesity (β = −6.58, p = 0.04) was significantly associated with decreased mental health among survivors, but not among controls. Obesity at baseline and follow-up were significantly associated with decreased physical health among survivors (baseline β = −10.51, p = 0.004; follow-up β = −7.16, p = 0.02) and controls (baseline β = −11.07, p < 0.001; follow-up β = −5.18, p = 0.04). No significant interactions between ethnicity and BMI were observed.
Conclusions
Our findings provide unique information about a diverse population of breast cancer survivors and controls and the impact of obesity on the mental and physical aspects of QOL.