Skip to main content
Erschienen in: Journal of Clinical Psychology in Medical Settings 4/2007

01.12.2007

Non-pharmacologic Interventions for CFS: A Randomized Trial

verfasst von: Leonard A. Jason, Susan Torres-Harding, Fred Friedberg, Katrina Corradi, Mary Gloria Njoku, Julie Donalek, Nadia Reynolds, Molly Brown, Bing Bing Weitner, Alfred Rademaker, Morris Papernik

Erschienen in: Journal of Clinical Psychology in Medical Settings | Ausgabe 4/2007

Einloggen, um Zugang zu erhalten

Abstract

Non-pharmacological behavioral treatments for CFS have been suggested as promising. These trials have tested protocols composed of behavioral, cognitive and cognitive–behavioral interventions but there have been few efforts to differentially evaluate their outcomes. The primary purpose of the current study was to evaluate the effectiveness of nurse delivered non-pharmacologic interventions. In the present study, 114 participants diagnosed with CFS were randomly assigned to four 6-month interventions. The interventions were: cognitive–behavior therapy, cognitive therapy, anaerobic activity, and a relaxation control group. The study found that these interventions led to increases in several areas of functioning, with more consistent changes occurring among those participants in the cognitive condition. For the 25 variables in this study, significant change occurred for 28%, 20%, 16%, and 12% of the variables for the cognitive, cognitive behavior therapy, anaerobic activity, and relaxation conditions, respectively. However, the majority of participants continued to be diagnosed with CFS following the treatment trial. Implications of these findings are discussed.
Literatur
Zurück zum Zitat Akagi, H., Klimes, I., & Bass, C. (2001). Cognitive behavioral therapy for chronic fatigue syndrome in a general hospital—feasible and effective. General Hospital Psychiatry, 23, 254–260.PubMedCrossRef Akagi, H., Klimes, I., & Bass, C. (2001). Cognitive behavioral therapy for chronic fatigue syndrome in a general hospital—feasible and effective. General Hospital Psychiatry, 23, 254–260.PubMedCrossRef
Zurück zum Zitat Antoni, M. H., Lutgendorf, S., Cole, S., Dhabhar, F., Sephton, S., McDonald, P., Stefanek, M., & Sood, A. (2006). The influence of biobehavioral factors on tumor biology, pathways and mechanisms. Nature Reviews Cancer, 6, 240–248.PubMedCrossRef Antoni, M. H., Lutgendorf, S., Cole, S., Dhabhar, F., Sephton, S., McDonald, P., Stefanek, M., & Sood, A. (2006). The influence of biobehavioral factors on tumor biology, pathways and mechanisms. Nature Reviews Cancer, 6, 240–248.PubMedCrossRef
Zurück zum Zitat Antoni, M. H., & Weiss, D. E. (2003). Stress and immunity. In L. A. Jason, P. A. Fennell, & R. R. Taylor (Eds.), Handbook of chronic fatigue syndrome (pp. 527–545). Hoboken: John Wiley & Sons. Antoni, M. H., & Weiss, D. E. (2003). Stress and immunity. In L. A. Jason, P. A. Fennell, & R. R. Taylor (Eds.), Handbook of chronic fatigue syndrome (pp. 527–545). Hoboken: John Wiley & Sons.
Zurück zum Zitat Bazelmans, E., Prins, J. B., Lulofs, R., van der Meer, J. W. M., & Bleijenberg, G. (2005). Cognitive behaviour group therapy for chronic fatigue syndrome. A nonrandomized waiting list controlled study. Psychotherapy and Psychosomatics, 74, 218–224.PubMedCrossRef Bazelmans, E., Prins, J. B., Lulofs, R., van der Meer, J. W. M., & Bleijenberg, G. (2005). Cognitive behaviour group therapy for chronic fatigue syndrome. A nonrandomized waiting list controlled study. Psychotherapy and Psychosomatics, 74, 218–224.PubMedCrossRef
Zurück zum Zitat Beck, A. T., Steer, R. A., & Brown, G. K. (1996). Manual for the Beck Depression Inventory-II. San Antonio: Psychological Corporation. Beck, A. T., Steer, R. A., & Brown, G. K. (1996). Manual for the Beck Depression Inventory-II. San Antonio: Psychological Corporation.
Zurück zum Zitat Black, C. D., O’Connor, P. J., & McCully, K. K. (2005). Increased daily physical activity and fatigue symptoms in chronic fatigue syndrome. Dynamic Medicine, 4, 3. doi: 10;1186/1476-5918-4-3. Black, C. D., O’Connor, P. J., & McCully, K. K. (2005). Increased daily physical activity and fatigue symptoms in chronic fatigue syndrome. Dynamic Medicine, 4, 3. doi:​ 10;1186/​1476-5918-4-3.
Zurück zum Zitat Buchwald, D., Pearlman, T., Umali, J., Schmaling, K., & Katon, W. (1996). Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals. American Journal of Medicine, 101, 364–370.PubMedCrossRef Buchwald, D., Pearlman, T., Umali, J., Schmaling, K., & Katon, W. (1996). Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals. American Journal of Medicine, 101, 364–370.PubMedCrossRef
Zurück zum Zitat Burckhardt, C. S., & Anderson, K. L. (2003). The Quality of Life Scale (QOLS): Reliability, validity, and utilization. Health and Quality of Life Outcomes, 1, 60.PubMedCrossRef Burckhardt, C. S., & Anderson, K. L. (2003). The Quality of Life Scale (QOLS): Reliability, validity, and utilization. Health and Quality of Life Outcomes, 1, 60.PubMedCrossRef
Zurück zum Zitat Butland, R. J. A., Pang, J., Gross, E. R., Woodcock, A. A., & Geddes, D. M. (1982). Two, six, and 12-minute walking tests in respiratory disease. British Medical Journal, 284, 1607–1608.PubMed Butland, R. J. A., Pang, J., Gross, E. R., Woodcock, A. A., & Geddes, D. M. (1982). Two, six, and 12-minute walking tests in respiratory disease. British Medical Journal, 284, 1607–1608.PubMed
Zurück zum Zitat Chambers, D., Bagnall, A. M., Hempel, S., & Forbes, C. (2006). Interventions for the treatment, management and rehabilitation of patients with chronic fatigue syndrome/myaglic encephalomyelitis: An updated systemic review. Journal of the Royal Society of Medicine, 99, 506–520.PubMedCrossRef Chambers, D., Bagnall, A. M., Hempel, S., & Forbes, C. (2006). Interventions for the treatment, management and rehabilitation of patients with chronic fatigue syndrome/myaglic encephalomyelitis: An updated systemic review. Journal of the Royal Society of Medicine, 99, 506–520.PubMedCrossRef
Zurück zum Zitat Chalder, T., Berelowitz, G., Pawlikowska, J., Watts, L., & Wessely, D. (1993). Development of a fatigue scale. Journal of Psychosomatic Research, 37, 147–153.PubMedCrossRef Chalder, T., Berelowitz, G., Pawlikowska, J., Watts, L., & Wessely, D. (1993). Development of a fatigue scale. Journal of Psychosomatic Research, 37, 147–153.PubMedCrossRef
Zurück zum Zitat Chengalur, S. N., Smith, G. A., Nelson, R. C., & Sadoff, A. M. (1990). Assessing sincerity of effort in maximal grip strength tests. American Journal of Physical Medicine and Rehabilitation, 69, 148–153.PubMed Chengalur, S. N., Smith, G. A., Nelson, R. C., & Sadoff, A. M. (1990). Assessing sincerity of effort in maximal grip strength tests. American Journal of Physical Medicine and Rehabilitation, 69, 148–153.PubMed
Zurück zum Zitat Cho, H. J., Hotopf, M., & Wessely, S. (2005). The placebo response in the treatment of chronic fatigue syndrome. A systematic review and meta-analysis. Psychosomatic Medicine, 67, 301–313.PubMedCrossRef Cho, H. J., Hotopf, M., & Wessely, S. (2005). The placebo response in the treatment of chronic fatigue syndrome. A systematic review and meta-analysis. Psychosomatic Medicine, 67, 301–313.PubMedCrossRef
Zurück zum Zitat Clapp, L. L., Richardson, M. T., Smith, J. F., Wang, M., Clapp, A. J., & Pieroni, R. E. (1999). Acute effects of thirty minutes of light-intensity, intermittent exercise on patients with chronic fatigue syndrome. Physical Therapy, 79, 749–756.PubMed Clapp, L. L., Richardson, M. T., Smith, J. F., Wang, M., Clapp, A. J., & Pieroni, R. E. (1999). Acute effects of thirty minutes of light-intensity, intermittent exercise on patients with chronic fatigue syndrome. Physical Therapy, 79, 749–756.PubMed
Zurück zum Zitat Cleeland, C. S., & Ryan, K. M. (1994). Pain assessment: The global use of the Brief Pain Inventory. Annals Academy of Medicine Singapore, 23, 129–138. Cleeland, C. S., & Ryan, K. M. (1994). Pain assessment: The global use of the Brief Pain Inventory. Annals Academy of Medicine Singapore, 23, 129–138.
Zurück zum Zitat Cohen, S., Kamark, T., & Mermelstein, R. (1983). A global measure of perceived stress. Journal of Health and Social Behavior, 37, 147–153. Cohen, S., Kamark, T., & Mermelstein, R. (1983). A global measure of perceived stress. Journal of Health and Social Behavior, 37, 147–153.
Zurück zum Zitat Cooper, L. (2001). Report on survey of members of local ME groups. Perspectives. Cooper, L. (2001). Report on survey of members of local ME groups. Perspectives.
Zurück zum Zitat Deale, A., Chalder, T., Marks, I., & Wessely, S. (1997). Cognitive behaviour therapy for chronic fatigue syndrome: A randomized controlled trial. American Journal of Psychiatry, 154, 408–414.PubMed Deale, A., Chalder, T., Marks, I., & Wessely, S. (1997). Cognitive behaviour therapy for chronic fatigue syndrome: A randomized controlled trial. American Journal of Psychiatry, 154, 408–414.PubMed
Zurück zum Zitat Deale, A., Husain, K., Chalder, T., & Wessely, S. (2001). Long-term outcome of cognitive behavior therapy versus relaxation therapy for chronic fatigue syndrome: A 5-year follow-up study. American Journal of Psychiatry, 158, 2038–2042.PubMedCrossRef Deale, A., Husain, K., Chalder, T., & Wessely, S. (2001). Long-term outcome of cognitive behavior therapy versus relaxation therapy for chronic fatigue syndrome: A 5-year follow-up study. American Journal of Psychiatry, 158, 2038–2042.PubMedCrossRef
Zurück zum Zitat Donta, S. T., Clauw, D. J., Engel, C. C., Guarino, P., Peduzzi, P., Williams, D. A., et al. (2003). Cognitive behavioral therapy and aerobic exercise for Gulf war veterans’ illnesses: A randomized controlled trial. Journal of the American Medical Association, 289, 1396–1404.PubMedCrossRef Donta, S. T., Clauw, D. J., Engel, C. C., Guarino, P., Peduzzi, P., Williams, D. A., et al. (2003). Cognitive behavioral therapy and aerobic exercise for Gulf war veterans’ illnesses: A randomized controlled trial. Journal of the American Medical Association, 289, 1396–1404.PubMedCrossRef
Zurück zum Zitat Edmonds, M., McGuire, H., & Price, J. (2004). Exercise therapy for chronic fatigue syndrome. The Cochrane Library, 3, 1–22. Edmonds, M., McGuire, H., & Price, J. (2004). Exercise therapy for chronic fatigue syndrome. The Cochrane Library, 3, 1–22.
Zurück zum Zitat Fennell, P. A. (1995). A four stage progressive model of CFS. Journal of Chronic Fatigue Syndrome, 1, 69–79.CrossRef Fennell, P. A. (1995). A four stage progressive model of CFS. Journal of Chronic Fatigue Syndrome, 1, 69–79.CrossRef
Zurück zum Zitat Ferguson, R. J., Robinson, A. B., & Splaine, M. (2002). Use of the Reliable Change Index to evaluate clinical significance in SF-36 outcomes. Quality of Life Research, 11, 509–516.PubMedCrossRef Ferguson, R. J., Robinson, A. B., & Splaine, M. (2002). Use of the Reliable Change Index to evaluate clinical significance in SF-36 outcomes. Quality of Life Research, 11, 509–516.PubMedCrossRef
Zurück zum Zitat Friedberg, F. (1996). Chronic fatigue syndrome: A new clinical application. Professional Psychology: Research and Practice, 27, 487–494.CrossRef Friedberg, F. (1996). Chronic fatigue syndrome: A new clinical application. Professional Psychology: Research and Practice, 27, 487–494.CrossRef
Zurück zum Zitat Friedberg, F., & Jason, L. A. (1998). Understanding chronic fatigue syndrome: An empirical guide to assessment and treatment. Washington: American Psychological Association. Friedberg, F., & Jason, L. A. (1998). Understanding chronic fatigue syndrome: An empirical guide to assessment and treatment. Washington: American Psychological Association.
Zurück zum Zitat Friedberg, F., & Krupp, L. B. (1994). A comparison of cognitive behavioral treatment for chronic fatigue syndrome and primary depression. Clinical Infectious Diseases, 18, 105–110. Friedberg, F., & Krupp, L. B. (1994). A comparison of cognitive behavioral treatment for chronic fatigue syndrome and primary depression. Clinical Infectious Diseases, 18, 105–110.
Zurück zum Zitat Fukuda, K., Straus, S. E., Hickie, I., Sharpe, M. C., Dobbins, J. G., & Komaroff, A. (1994). The chronic fatigue syndrome: A comprehensive approach to its definition and study. Annals of Internal Medicine, 121, 953–959.PubMed Fukuda, K., Straus, S. E., Hickie, I., Sharpe, M. C., Dobbins, J. G., & Komaroff, A. (1994). The chronic fatigue syndrome: A comprehensive approach to its definition and study. Annals of Internal Medicine, 121, 953–959.PubMed
Zurück zum Zitat Fulcher, K. Y., & White, P. D. (1997). Randomized controlled trial of graded exercise in patients with the chronic fatigue syndrome. British Medical Journal, 314, 1647–1652.PubMed Fulcher, K. Y., & White, P. D. (1997). Randomized controlled trial of graded exercise in patients with the chronic fatigue syndrome. British Medical Journal, 314, 1647–1652.PubMed
Zurück zum Zitat Gabbe, B. J., Bennell, K. L., Wajswelner, H., & Finch, C. F. (2004). Reliability of common lower extremity musculoskeletal screening tests. Physical Therapy in Sport, 5, 90–97. Gabbe, B. J., Bennell, K. L., Wajswelner, H., & Finch, C. F. (2004). Reliability of common lower extremity musculoskeletal screening tests. Physical Therapy in Sport, 5, 90–97.
Zurück zum Zitat Goudsmit, E. (2001). Measuring the quality of trials of treatments for chronic fatigue syndrome. Journal of the American Medical Association, 286, 3078–3079.PubMedCrossRef Goudsmit, E. (2001). Measuring the quality of trials of treatments for chronic fatigue syndrome. Journal of the American Medical Association, 286, 3078–3079.PubMedCrossRef
Zurück zum Zitat Gould, R., Abramson, I., Galasko, D., & Salmon, D. (2001). Rate of cognitive change in Alzheimer’s disease: Methodological approaches using random effects models. Journal of the International Neuropsychological Society, 7, 813–824.PubMed Gould, R., Abramson, I., Galasko, D., & Salmon, D. (2001). Rate of cognitive change in Alzheimer’s disease: Methodological approaches using random effects models. Journal of the International Neuropsychological Society, 7, 813–824.PubMed
Zurück zum Zitat Hawk, C., Jason, L. A., & Torres-Harding, S. (2007). Reliability of a chronic fatigue syndrome questionnaire. Journal of Chronic Fatigue Syndrome, 13, 41–66.CrossRef Hawk, C., Jason, L. A., & Torres-Harding, S. (2007). Reliability of a chronic fatigue syndrome questionnaire. Journal of Chronic Fatigue Syndrome, 13, 41–66.CrossRef
Zurück zum Zitat Hewitt, P. L., & Norton, G. R. (1993). The Beck Anxiety Inventory: A psychometric analysis. Psychological Assessment, 5, 408–412.CrossRef Hewitt, P. L., & Norton, G. R. (1993). The Beck Anxiety Inventory: A psychometric analysis. Psychological Assessment, 5, 408–412.CrossRef
Zurück zum Zitat Huibers, M. J. H., Beurskens, A. J. H. M., van Schayck, C. P., Bazelmans, E., Metsemakers, J. F. M., Knottnerus, J. A., et al. (2004). Efficacy of cognitive-behavioral therapy by general practitioners for unexplained fatigue among employees. The British Journal of Psychiatry, 184, 240–246.PubMedCrossRef Huibers, M. J. H., Beurskens, A. J. H. M., van Schayck, C. P., Bazelmans, E., Metsemakers, J. F. M., Knottnerus, J. A., et al. (2004). Efficacy of cognitive-behavioral therapy by general practitioners for unexplained fatigue among employees. The British Journal of Psychiatry, 184, 240–246.PubMedCrossRef
Zurück zum Zitat Innes, E. (1999). Handgrip strength testing: A review of the literature. Australian Occupational Therapy Journal, 46, 120–140.CrossRef Innes, E. (1999). Handgrip strength testing: A review of the literature. Australian Occupational Therapy Journal, 46, 120–140.CrossRef
Zurück zum Zitat Jason, L. A., Melrose, H., Lerman, A., Burroughs, V., Lewis, K., King, C. P., et al. (1999). Managing chronic fatigue syndrome: A case study. AAOHN Journal, 47, 17–21.PubMed Jason, L. A., Melrose, H., Lerman, A., Burroughs, V., Lewis, K., King, C. P., et al. (1999). Managing chronic fatigue syndrome: A case study. AAOHN Journal, 47, 17–21.PubMed
Zurück zum Zitat Jason, L. A., Ropacki, J. A., Santoro, N. B., Richman, J. A., Heatherly, W., Taylor, R., et al. (1997). A screening scale for chronic fatigue syndrome: Reliability and validity. Journal of Chronic Fatigue Syndrome, 3, 39–59.CrossRef Jason, L. A., Ropacki, J. A., Santoro, N. B., Richman, J. A., Heatherly, W., Taylor, R., et al. (1997). A screening scale for chronic fatigue syndrome: Reliability and validity. Journal of Chronic Fatigue Syndrome, 3, 39–59.CrossRef
Zurück zum Zitat Jensen, M. P., & Karoly, P. (1992). Self-report scales and procedures for assessing pain in adults. In D. C. Turk & R. Melzack (Eds.), Handbook of pain assessment (pp. 135–151). New York: Guilford Press. Jensen, M. P., & Karoly, P. (1992). Self-report scales and procedures for assessing pain in adults. In D. C. Turk & R. Melzack (Eds.), Handbook of pain assessment (pp. 135–151). New York: Guilford Press.
Zurück zum Zitat Johnson, S. K., DeLuca, J., & Natelson, B. (1996). Depression in fatiguing illness: Comparing patients with chronic fatigue syndrome, multiple sclerosis and depression. Journal of Affective Disorders, 39, 21–30.PubMedCrossRef Johnson, S. K., DeLuca, J., & Natelson, B. (1996). Depression in fatiguing illness: Comparing patients with chronic fatigue syndrome, multiple sclerosis and depression. Journal of Affective Disorders, 39, 21–30.PubMedCrossRef
Zurück zum Zitat Keller, S., Bann, C. M., Dodd, S. L., Schein, J., Mendoza, T. R., & Cleeland, C. S. (2004). Validity of the Brief Pain Inventory for use in documenting the outcomes of patients with noncancer pain. The Clinical Journal of Pain, 20, 309–318.PubMedCrossRef Keller, S., Bann, C. M., Dodd, S. L., Schein, J., Mendoza, T. R., & Cleeland, C. S. (2004). Validity of the Brief Pain Inventory for use in documenting the outcomes of patients with noncancer pain. The Clinical Journal of Pain, 20, 309–318.PubMedCrossRef
Zurück zum Zitat Komaroff, A. L., Fagioli, L. R., Geiger, A. M., Doolittle, T. H., Lee, J., Kornish, R. J., et al. (1996). An examination of the working case definition of chronic fatigue syndrome. American Journal of Medicine, 100, 56–64.PubMedCrossRef Komaroff, A. L., Fagioli, L. R., Geiger, A. M., Doolittle, T. H., Lee, J., Kornish, R. J., et al. (1996). An examination of the working case definition of chronic fatigue syndrome. American Journal of Medicine, 100, 56–64.PubMedCrossRef
Zurück zum Zitat Krupp, L. B., LaRocca, N. G., Muir-Nash, J., & Steinberg, A. D. (1989). The Fatigue Severity Scale: Application to patents with multiple sclerosis and systemic Lupus erythematosus. Archives of Neurology, 46, 1121–1123.PubMed Krupp, L. B., LaRocca, N. G., Muir-Nash, J., & Steinberg, A. D. (1989). The Fatigue Severity Scale: Application to patents with multiple sclerosis and systemic Lupus erythematosus. Archives of Neurology, 46, 1121–1123.PubMed
Zurück zum Zitat Laird, N., & Ware, J. (1982). Random-effects models for longitudinal data. Biometrics, 38, 963–974.PubMedCrossRef Laird, N., & Ware, J. (1982). Random-effects models for longitudinal data. Biometrics, 38, 963–974.PubMedCrossRef
Zurück zum Zitat McGregor, B., Antoni, M., Boyers, A., Alferi, S., Blomberg, B., Carver, C. (2004). Cognitive–behavioral stress management increases benefit finding and immune function among women with early-stage breast cancer. Journal of Psychosomatic Research, 56, 1–8.PubMedCrossRef McGregor, B., Antoni, M., Boyers, A., Alferi, S., Blomberg, B., Carver, C. (2004). Cognitive–behavioral stress management increases benefit finding and immune function among women with early-stage breast cancer. Journal of Psychosomatic Research, 56, 1–8.PubMedCrossRef
Zurück zum Zitat McHorney, C. A., Ware, J. E., Lu, A. W., & Sherbourne, C. D. (1994). The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Medical Care, 32, 40–66.PubMedCrossRef McHorney, C. A., Ware, J. E., Lu, A. W., & Sherbourne, C. D. (1994). The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Medical Care, 32, 40–66.PubMedCrossRef
Zurück zum Zitat McKenzie, M., Dechene, L., Friedberg, F., & Fontanetta, R. (1995). Cognitive-behavioral coping skills in long-term chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome, 1, 59–67.CrossRef McKenzie, M., Dechene, L., Friedberg, F., & Fontanetta, R. (1995). Cognitive-behavioral coping skills in long-term chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome, 1, 59–67.CrossRef
Zurück zum Zitat Miller, G. E., & Cohen, S. (2001). Psychological interventions and the immune system: A meta-analytic review and critique. Health Psychology, 20, 47–63.PubMedCrossRef Miller, G. E., & Cohen, S. (2001). Psychological interventions and the immune system: A meta-analytic review and critique. Health Psychology, 20, 47–63.PubMedCrossRef
Zurück zum Zitat Ost, L. (1987). Applied relaxation: Description of a coping technique and review of controlled studies. Behavior Research and Therapy, 25, 397–409.CrossRef Ost, L. (1987). Applied relaxation: Description of a coping technique and review of controlled studies. Behavior Research and Therapy, 25, 397–409.CrossRef
Zurück zum Zitat Peckerman, A., LaManca, J. J., Dahl, K. A., Chemitiganti, R., Qureishi, B., & Natelson, B. H. (2003). Abnormal impedance cardiography predicts symptom severity in chronic fatigue syndrome. The American Journal of the Medical Sciences, 326, 55–60.PubMedCrossRef Peckerman, A., LaManca, J. J., Dahl, K. A., Chemitiganti, R., Qureishi, B., & Natelson, B. H. (2003). Abnormal impedance cardiography predicts symptom severity in chronic fatigue syndrome. The American Journal of the Medical Sciences, 326, 55–60.PubMedCrossRef
Zurück zum Zitat Pepper, C. M., Krupp, L. B., Friedberg, F., Doscher, C., & Coyle, P. K. (1993). A comparison of neuropsychiatric characteristics in chronic fatigue syndrome, multiple sclerosis, and major depression. The Journal of Neuropsychiatry and Clinical Neurosciences, 5, 200–205.PubMed Pepper, C. M., Krupp, L. B., Friedberg, F., Doscher, C., & Coyle, P. K. (1993). A comparison of neuropsychiatric characteristics in chronic fatigue syndrome, multiple sclerosis, and major depression. The Journal of Neuropsychiatry and Clinical Neurosciences, 5, 200–205.PubMed
Zurück zum Zitat Powell, P., Bentall, R. P., Nye, F. J., & Edwards, R. H. T. (2001). Randomized controlled trial of patient education to encourage exercise in chronic fatigue syndrome. British Medical Journal, 322, 1–5.CrossRef Powell, P., Bentall, R. P., Nye, F. J., & Edwards, R. H. T. (2001). Randomized controlled trial of patient education to encourage exercise in chronic fatigue syndrome. British Medical Journal, 322, 1–5.CrossRef
Zurück zum Zitat Powell, P., Bentall, R. P., Nye, F. J., & Edwards, R. H. T. (2004). Patient education to encourage graded exercise in chronic fatigue syndrome – 2-year follow-up randomized controlled trial. The British Journal of Psychiatry, 184, 142–146.PubMedCrossRef Powell, P., Bentall, R. P., Nye, F. J., & Edwards, R. H. T. (2004). Patient education to encourage graded exercise in chronic fatigue syndrome – 2-year follow-up randomized controlled trial. The British Journal of Psychiatry, 184, 142–146.PubMedCrossRef
Zurück zum Zitat Preliminary Report. (2001). The severely affected. AfME, Feb., 28, 2001. Preliminary Report. (2001). The severely affected. AfME, Feb., 28, 2001.
Zurück zum Zitat Prins, J. B., Bleijenberg, G., Bazelmans, E., Elving, L. D., De Boo, T. M., Severens, J. L., et al. (2001). Cognitive behaviour therapy for chronic fatigue syndrome: A multicenter randomized controlled trial. Lancet, 357, 841–847.PubMedCrossRef Prins, J. B., Bleijenberg, G., Bazelmans, E., Elving, L. D., De Boo, T. M., Severens, J. L., et al. (2001). Cognitive behaviour therapy for chronic fatigue syndrome: A multicenter randomized controlled trial. Lancet, 357, 841–847.PubMedCrossRef
Zurück zum Zitat Ridsdale, L., Godfrey, E., Chalder, T., Seed, P., King, M., Wallace, P., et al. (2001). Chronic fatigue in general practice: Is counseling as good as cognitive behaviour therapy? A randomized trial. British Journal of General Practice, 51, 19–24.PubMed Ridsdale, L., Godfrey, E., Chalder, T., Seed, P., King, M., Wallace, P., et al. (2001). Chronic fatigue in general practice: Is counseling as good as cognitive behaviour therapy? A randomized trial. British Journal of General Practice, 51, 19–24.PubMed
Zurück zum Zitat Ridsdale, L., Darbishire, L., & Seed, P. (2004). Is graded exercise better than cognitive behavior therapy for fatigue? A UK randomized trial in primary care. Psychological Medicine, 34, 37–49.PubMedCrossRef Ridsdale, L., Darbishire, L., & Seed, P. (2004). Is graded exercise better than cognitive behavior therapy for fatigue? A UK randomized trial in primary care. Psychological Medicine, 34, 37–49.PubMedCrossRef
Zurück zum Zitat Robinson, G. K. (1991). The BLUP is a good thing: The estimation of random effects. Statistical Science, 6, 15–51. Robinson, G. K. (1991). The BLUP is a good thing: The estimation of random effects. Statistical Science, 6, 15–51.
Zurück zum Zitat Severens, J. L., Prins, J. B., Van Wilt, G. J. Van Meer, J. W. M., & Bleijenberg, G. (2004). Cost-effectiveness of cognitive behavior therapy for patients with chronic fatigue syndrome. Quarterly Journal of Medicine, 97, 153–161. Severens, J. L., Prins, J. B., Van Wilt, G. J. Van Meer, J. W. M., & Bleijenberg, G. (2004). Cost-effectiveness of cognitive behavior therapy for patients with chronic fatigue syndrome. Quarterly Journal of Medicine, 97, 153–161.
Zurück zum Zitat Sharpe, M., Hawton, K., Simkin, S., Surawy, C., Hackmann, A., Klimes, I., et al. (1996). Cognitive behavior therapy for the chronic fatigue syndrome: A randomized controlled trial. British Medical Journal, 312, 22–26.PubMed Sharpe, M., Hawton, K., Simkin, S., Surawy, C., Hackmann, A., Klimes, I., et al. (1996). Cognitive behavior therapy for the chronic fatigue syndrome: A randomized controlled trial. British Medical Journal, 312, 22–26.PubMed
Zurück zum Zitat Soderberg, S., & Evengard, B. (2001). Short-term group therapy for patients with chronic fatigue syndrome. Psychotherapy Psychosomatics, 70, 108–111.CrossRef Soderberg, S., & Evengard, B. (2001). Short-term group therapy for patients with chronic fatigue syndrome. Psychotherapy Psychosomatics, 70, 108–111.CrossRef
Zurück zum Zitat Song, S., & Jason, L. A. (2005). A population-based study of chronic fatigue syndrome (CFS) experienced in differing patient groups: An effort to replicate Vercoulen et al.’s model of CFS. Journal of Mental Health, 14, 277–289.CrossRef Song, S., & Jason, L. A. (2005). A population-based study of chronic fatigue syndrome (CFS) experienced in differing patient groups: An effort to replicate Vercoulen et al.’s model of CFS. Journal of Mental Health, 14, 277–289.CrossRef
Zurück zum Zitat Spitzer, R. L., Williams, J. B. W., Gibbon, M., & First, M. B. (1995). Structured Clinical Interview for the DSM-IV—non-patient edition (SCID—NP, version 2.0). Washington: American Psychiatric Press. Spitzer, R. L., Williams, J. B. W., Gibbon, M., & First, M. B. (1995). Structured Clinical Interview for the DSM-IV—non-patient edition (SCID—NP, version 2.0). Washington: American Psychiatric Press.
Zurück zum Zitat Steer, R. A., Clark, D. A., Beck, A. T., & Ranieri, W. F. (1995). Common and specific dimensions of self-reported anxiety and depression: A replication. Journal of Abnormal Psychology, 104, 542–545.PubMedCrossRef Steer, R. A., Clark, D. A., Beck, A. T., & Ranieri, W. F. (1995). Common and specific dimensions of self-reported anxiety and depression: A replication. Journal of Abnormal Psychology, 104, 542–545.PubMedCrossRef
Zurück zum Zitat Surawy, C., Hackmann, A., Hawton, K., & Sharpe, M. (1995). Chronic fatigue syndrome: A cognitive approach. Behavior Research Therapy, 33, 535–544.CrossRef Surawy, C., Hackmann, A., Hawton, K., & Sharpe, M. (1995). Chronic fatigue syndrome: A cognitive approach. Behavior Research Therapy, 33, 535–544.CrossRef
Zurück zum Zitat Taylor, R. R., & Jason, L. A. (1998). Comparing the DIS with the SCID: Chronic fatigue syndrome and psychiatric comorbidity. Psychology and Health: The International Review of Health Psychology, 13, 1087–1104. Taylor, R. R., & Jason, L. A. (1998). Comparing the DIS with the SCID: Chronic fatigue syndrome and psychiatric comorbidity. Psychology and Health: The International Review of Health Psychology, 13, 1087–1104.
Zurück zum Zitat Taylor, R. R., Jason, L. A., Shiraishi, Y., Schoeny, M. E., & Keller, J. (2006). Conservation of resources theory, perceived stress, and chronic fatigue syndrome: Outcomes of a consumer-driven rehabilitation program. Rehabilitation Psychology, 51, 157–165.CrossRef Taylor, R. R., Jason, L. A., Shiraishi, Y., Schoeny, M. E., & Keller, J. (2006). Conservation of resources theory, perceived stress, and chronic fatigue syndrome: Outcomes of a consumer-driven rehabilitation program. Rehabilitation Psychology, 51, 157–165.CrossRef
Zurück zum Zitat Taylor, R. R., Jason, L. A., & Torres, A. (2000). Fatigue rating scales: An empirical comparison. Psychological Medicine, 30, 849–856.PubMedCrossRef Taylor, R. R., Jason, L. A., & Torres, A. (2000). Fatigue rating scales: An empirical comparison. Psychological Medicine, 30, 849–856.PubMedCrossRef
Zurück zum Zitat Van der Werf, S. P., de Vree, B., Alberts, M., van der Meer, J. W. M., & Bleijenberg, G. (2002). Natural course and predicting self-reported improvement in patients with chronic fatigue syndrome with a relatively short illness duration. Journal of Psychosomatic Research, 53, 749–753.PubMedCrossRef Van der Werf, S. P., de Vree, B., Alberts, M., van der Meer, J. W. M., & Bleijenberg, G. (2002). Natural course and predicting self-reported improvement in patients with chronic fatigue syndrome with a relatively short illness duration. Journal of Psychosomatic Research, 53, 749–753.PubMedCrossRef
Zurück zum Zitat Van Hoof, E. (2004). Cognitive behavioral therapy as cure-all for CFS. Journal of Chronic Fatigue Syndrome, 11, 43–47.CrossRef Van Hoof, E. (2004). Cognitive behavioral therapy as cure-all for CFS. Journal of Chronic Fatigue Syndrome, 11, 43–47.CrossRef
Zurück zum Zitat Vercoulen, J. H., Swanink, C. M., Galama, J. M., Fennis, J. F., Jongen, P. J., Hommes, O. R., et al. (1998). The persistence of fatigue in chronic fatigue syndrome and multiple sclerosis: Development of a model. Journal of Psychosomatic Research, 45, 507–517.PubMedCrossRef Vercoulen, J. H., Swanink, C. M., Galama, J. M., Fennis, J. F., Jongen, P. J., Hommes, O. R., et al. (1998). The persistence of fatigue in chronic fatigue syndrome and multiple sclerosis: Development of a model. Journal of Psychosomatic Research, 45, 507–517.PubMedCrossRef
Zurück zum Zitat Wallman, K. E., Morton, A. R., Goodman, C., Grove, R., & Guilfoyle, A. M. (2004). Randomised controlled trial of graded exercise in chronic fatigue syndrome. The Medical Journal of Australia, 180, 444–448.PubMed Wallman, K. E., Morton, A. R., Goodman, C., Grove, R., & Guilfoyle, A. M. (2004). Randomised controlled trial of graded exercise in chronic fatigue syndrome. The Medical Journal of Australia, 180, 444–448.PubMed
Zurück zum Zitat Ware, J. E., & Sherbourne, C. D. (1992). The MOS 36-item short-form health survey. Medical Care, 30, 473–483.PubMedCrossRef Ware, J. E., & Sherbourne, C. D. (1992). The MOS 36-item short-form health survey. Medical Care, 30, 473–483.PubMedCrossRef
Zurück zum Zitat Wearden, A. J., Morriss, R. K., Mullis, R., Strickland, P. L., Pearson, D. J., & Appleby, L. (1998). Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome. The British Journal of Psychiatry, 172, 485–490.PubMedCrossRef Wearden, A. J., Morriss, R. K., Mullis, R., Strickland, P. L., Pearson, D. J., & Appleby, L. (1998). Randomised, double-blind, placebo-controlled treatment trial of fluoxetine and graded exercise for chronic fatigue syndrome. The British Journal of Psychiatry, 172, 485–490.PubMedCrossRef
Zurück zum Zitat White, P. D., Sharpe, M. C., Chalder, T., DeCesare, J. C., & Walwyn, R. (2007). Protocol for the PACE trial: A randomised controlled trial of adaptive pacing, cognitive behaviour therapy, and graded exercise, as supplements to standardised specialist medical care versus standardised specialist medical care alone for patients with the chronic fatigue syndrome/myalgic encephalomyelitis or encephalopathy. BMC Neurology, 7, 6. doi: 10.1186/1471-2377-7-6. White, P. D., Sharpe, M. C., Chalder, T., DeCesare, J. C., & Walwyn, R. (2007). Protocol for the PACE trial: A randomised controlled trial of adaptive pacing, cognitive behaviour therapy, and graded exercise, as supplements to standardised specialist medical care versus standardised specialist medical care alone for patients with the chronic fatigue syndrome/myalgic encephalomyelitis or encephalopathy. BMC Neurology, 7, 6. doi:​ 10.​1186/​1471-2377-7-6.
Zurück zum Zitat Whitehead, L., & Campion, P. (2002). Can general practitioners manage chronic fatigue syndrome? A controlled trial. Journal of Chronic Fatigue Syndrome, 10, 55–64.CrossRef Whitehead, L., & Campion, P. (2002). Can general practitioners manage chronic fatigue syndrome? A controlled trial. Journal of Chronic Fatigue Syndrome, 10, 55–64.CrossRef
Zurück zum Zitat Whiteside, A., Hansen, S., & Chaudhuri, A. (2004). Exercise lowers pain threshold in chronic fatigue syndrome. Pain, 109, 497–499.PubMedCrossRef Whiteside, A., Hansen, S., & Chaudhuri, A. (2004). Exercise lowers pain threshold in chronic fatigue syndrome. Pain, 109, 497–499.PubMedCrossRef
Zurück zum Zitat Whiting, P., Bagnall, A. M., Sowden, A. J., Cornell, J. E., Mulrow, C. D., & Ramirez, G. (2001). Interventions for the treatment and management of chronic fatigue syndrome. Journal of the American Medical Association, 286, 1360–1368.PubMedCrossRef Whiting, P., Bagnall, A. M., Sowden, A. J., Cornell, J. E., Mulrow, C. D., & Ramirez, G. (2001). Interventions for the treatment and management of chronic fatigue syndrome. Journal of the American Medical Association, 286, 1360–1368.PubMedCrossRef
Zurück zum Zitat Wood, B., & Wessely, S. (1999). Personality and social attitudes in chronic fatigue syndrome. Journal of Psychosomatic Research, 47, 385–397.PubMedCrossRef Wood, B., & Wessely, S. (1999). Personality and social attitudes in chronic fatigue syndrome. Journal of Psychosomatic Research, 47, 385–397.PubMedCrossRef
Metadaten
Titel
Non-pharmacologic Interventions for CFS: A Randomized Trial
verfasst von
Leonard A. Jason
Susan Torres-Harding
Fred Friedberg
Katrina Corradi
Mary Gloria Njoku
Julie Donalek
Nadia Reynolds
Molly Brown
Bing Bing Weitner
Alfred Rademaker
Morris Papernik
Publikationsdatum
01.12.2007
Verlag
Springer US
Erschienen in
Journal of Clinical Psychology in Medical Settings / Ausgabe 4/2007
Print ISSN: 1068-9583
Elektronische ISSN: 1573-3572
DOI
https://doi.org/10.1007/s10880-007-9090-7

Weitere Artikel der Ausgabe 4/2007

Journal of Clinical Psychology in Medical Settings 4/2007 Zur Ausgabe