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Erschienen in: Maternal and Child Health Journal 3/2011

01.04.2011

U.S. Provider Reported Folic Acid or Multivitamin Ordering for Non-Pregnant Women of Childbearing Age: NAMCS and NHAMCS, 2005–2006

verfasst von: Heather H. Burris, Martha M. Werler

Erschienen in: Maternal and Child Health Journal | Ausgabe 3/2011

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Abstract

Folic acid use started prior to pregnancy confers a decreased risk of neural tube defects, and yet 20–50% of pregnancies are unplanned. We sought to determine whether medical providers order folic acid (FA) or folic acid-containing multivitamins (MVI) for their non-pregnant female patients of childbearing age. This is a cross-sectional study using data from the CDC’s National Ambulatory Medical Care Survey (NAMCS) and National Hospital Ambulatory Medical Care Survey (NHAMCS) (2005 and 2006). Among non-pregnant, female patients of childbearing age (15–44), the proportion of preventive visits during which a provider ordered FA/MVI supplements was determined and compared to pregnant patients. Next, the rates of FA/MVI orders were examined according to race/ethnicity, age, insurance status, region of the country, provider type, contraceptive care, income and education. Analyses were conducted using SAS-callable Sudaan to account for survey design and to obtain population estimates. There were 4,634 preventive visits for non-pregnant women of childbearing age, representing 32.1 million visits nationally. Of these visits, 7.2% included provider-ordered FA/MVI. Multivariable logistic regression analyses revealed that provider-ordered FA/MVI was most common for women ages 30–34, who receive Medicaid, and whose race/ethnicity was other than White, Black or Hispanic. Preventive care visits represent an important venue for counseling regarding the benefits of FA for women of childbearing age, but appear to be under-utilized in all women. Our findings suggest that annually there may be over 29 million missed opportunities to recommend folic acid to non-pregnant women seeking preventive care.
Literatur
1.
Zurück zum Zitat MRC Vitamin Study Research Group. (1991). Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study. Mrc Vitamin Study Research Group. Lancet, 338, 131–137.CrossRef MRC Vitamin Study Research Group. (1991). Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study. Mrc Vitamin Study Research Group. Lancet, 338, 131–137.CrossRef
2.
Zurück zum Zitat Laurence, K. M., James, N., Miller, M. H., Tennant, G. B., & Campbell, H. (1981). Double-blind randomised controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects. British Medical Journal (Clinical Research ed.), 282, 1509–1511.CrossRef Laurence, K. M., James, N., Miller, M. H., Tennant, G. B., & Campbell, H. (1981). Double-blind randomised controlled trial of folate treatment before conception to prevent recurrence of neural-tube defects. British Medical Journal (Clinical Research ed.), 282, 1509–1511.CrossRef
3.
Zurück zum Zitat Werler, M. M., Shapiro, S., & Mitchell, A. A. (1993). Periconceptional folic acid exposure and risk of occurrent neural tube defects. JAMA, 269, 1257–1261.PubMedCrossRef Werler, M. M., Shapiro, S., & Mitchell, A. A. (1993). Periconceptional folic acid exposure and risk of occurrent neural tube defects. JAMA, 269, 1257–1261.PubMedCrossRef
4.
Zurück zum Zitat Kuroki, L. M., Allsworth, J. E., Redding, C. A., Blume, J. D., & Peipert, J. F. (2008). Is a previous unplanned pregnancy a risk factor for a subsequent unplanned pregnancy? American Journal of Obstetrics and Gynecology, 199(5), 517.e1–517.e7CrossRef Kuroki, L. M., Allsworth, J. E., Redding, C. A., Blume, J. D., & Peipert, J. F. (2008). Is a previous unplanned pregnancy a risk factor for a subsequent unplanned pregnancy? American Journal of Obstetrics and Gynecology, 199(5), 517.e1–517.e7CrossRef
5.
Zurück zum Zitat Wilson, R. D., Davies, G., Desilets, V., Reid, G. J., Summers, A., Wyatt, P., et al. (2003). The use of folic acid for the prevention of neural tube defects and other congenital anomalies. Journal of Obstetrics and Gynaecology Canada, 25, 959–973.PubMed Wilson, R. D., Davies, G., Desilets, V., Reid, G. J., Summers, A., Wyatt, P., et al. (2003). The use of folic acid for the prevention of neural tube defects and other congenital anomalies. Journal of Obstetrics and Gynaecology Canada, 25, 959–973.PubMed
6.
Zurück zum Zitat Finer, L. B., & Henshaw, S. K. (2006). Disparities in rates of unintended pregnancy in the United States, 1994 and 2001. Perspectives on Sexual and Reproductive Health, 38, 90–96.PubMedCrossRef Finer, L. B., & Henshaw, S. K. (2006). Disparities in rates of unintended pregnancy in the United States, 1994 and 2001. Perspectives on Sexual and Reproductive Health, 38, 90–96.PubMedCrossRef
7.
Zurück zum Zitat Beck, L. F., Morrow, B., Lipscomb, L. E., Johnson, C. H., Gaffield, M. E., Rogers, M., et al. (2002). Prevalence of selected maternal behaviors and experiences, pregnancy risk assessment monitoring system (Prams), 1999. MMWR Surveillance Summaries, 51, 1–27. Beck, L. F., Morrow, B., Lipscomb, L. E., Johnson, C. H., Gaffield, M. E., Rogers, M., et al. (2002). Prevalence of selected maternal behaviors and experiences, pregnancy risk assessment monitoring system (Prams), 1999. MMWR Surveillance Summaries, 51, 1–27.
8.
Zurück zum Zitat Henshaw, S. K. (1998). Unintended pregnancy in the United States. Family Planning Perspectives, 30, 24–29. 46.PubMedCrossRef Henshaw, S. K. (1998). Unintended pregnancy in the United States. Family Planning Perspectives, 30, 24–29. 46.PubMedCrossRef
9.
Zurück zum Zitat Dott, M., Rasmussen, S. A., Hogue, C. J., & Reefhuis J. (2009). Association between pregnancy intention and reproductive-health related behaviors before and after pregnancy recognition, National Birth Defects Prevention Study, 1997–2002. Maternal and Child Health Journal (Epub ahead of print, February 28, 2009). doi:10.1007/s10995-009-0458-1. Dott, M., Rasmussen, S. A., Hogue, C. J., & Reefhuis J. (2009). Association between pregnancy intention and reproductive-health related behaviors before and after pregnancy recognition, National Birth Defects Prevention Study, 1997–2002. Maternal and Child Health Journal (Epub ahead of print, February 28, 2009). doi:10.​1007/​s10995-009-0458-1.
10.
Zurück zum Zitat U.S. Preventive Services Task Force. (2009). Folic acid for the prevention of neural tube defects: U.S. preventive services task force recommendation statement. Annals of Internal Medicine, 150, 626–631. U.S. Preventive Services Task Force. (2009). Folic acid for the prevention of neural tube defects: U.S. preventive services task force recommendation statement. Annals of Internal Medicine, 150, 626–631.
12.
Zurück zum Zitat Centers for Disease Control and Prevention. (1992). Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR Recommendations and Reports, 41, 1–7. Centers for Disease Control and Prevention. (1992). Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR Recommendations and Reports, 41, 1–7.
13.
Zurück zum Zitat Food and Nutrition Board, Institute of Medicine, Subcommittee on Upper Reference Levels of Nutrients. (2000). Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotine, and coholine; a report of the standing committee on the scientific evaluation of dietary reference intakes and its panel on folate, other B vitamins, and choline. Washington, D.C.: National Academy Press. Food and Nutrition Board, Institute of Medicine, Subcommittee on Upper Reference Levels of Nutrients. (2000). Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotine, and coholine; a report of the standing committee on the scientific evaluation of dietary reference intakes and its panel on folate, other B vitamins, and choline. Washington, D.C.: National Academy Press.
14.
Zurück zum Zitat Cleves, M. A., Hobbs, C. A., Collins, H. B., Andrews, N., Smith, L. N., & Robbins, J. M. (2004). Folic acid use by women receiving routine gynecologic care. Obstetrics and Gynecology, 103, 746–753.PubMedCrossRef Cleves, M. A., Hobbs, C. A., Collins, H. B., Andrews, N., Smith, L. N., & Robbins, J. M. (2004). Folic acid use by women receiving routine gynecologic care. Obstetrics and Gynecology, 103, 746–753.PubMedCrossRef
15.
Zurück zum Zitat Sullivan, K. M., Ford, E. S., Azrak, M., Fuad, M., & Ali, H. (2009). Multivitamin use in pregnant and nonpregnant women: Results from the behavioral risk factor surveillance system. Public Health Reports, 124, 7. Sullivan, K. M., Ford, E. S., Azrak, M., Fuad, M., & Ali, H. (2009). Multivitamin use in pregnant and nonpregnant women: Results from the behavioral risk factor surveillance system. Public Health Reports, 124, 7.
16.
Zurück zum Zitat Johnston, R. (2009). Folic acid: Preventive nutrition for preconception, the fetus, and the newborn. NeoReviews, 10, e10–e19.CrossRef Johnston, R. (2009). Folic acid: Preventive nutrition for preconception, the fetus, and the newborn. NeoReviews, 10, e10–e19.CrossRef
17.
Zurück zum Zitat Honein, M. A., Paulozzi, L. J., Mathews, T. J., Erickson, J. D., & Wong, L. Y. (2001). Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. JAMA, 285, 2981–2986.PubMedCrossRef Honein, M. A., Paulozzi, L. J., Mathews, T. J., Erickson, J. D., & Wong, L. Y. (2001). Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. JAMA, 285, 2981–2986.PubMedCrossRef
18.
Zurück zum Zitat Food and Drug Administration. (1996). Food additives permitted for direct addition to food for human consumption; folic acid (folacin), final rule. Federal Register, 61, 8797–8807. Food and Drug Administration. (1996). Food additives permitted for direct addition to food for human consumption; folic acid (folacin), final rule. Federal Register, 61, 8797–8807.
19.
Zurück zum Zitat Ganji, V., & Kafai, M. R. (2006). Trends in serum folate, Rbc folate, and circulating total homocysteine concentrations in the United States: Analysis of data from National Health and Nutrition Examination Surveys, 1988–1994, 1999–2000, and 2001–2002. Journal of Nutrition, 136, 153–158.PubMed Ganji, V., & Kafai, M. R. (2006). Trends in serum folate, Rbc folate, and circulating total homocysteine concentrations in the United States: Analysis of data from National Health and Nutrition Examination Surveys, 1988–1994, 1999–2000, and 2001–2002. Journal of Nutrition, 136, 153–158.PubMed
20.
Zurück zum Zitat Yang, Q. H., Carter, H. K., Mulinare, J., Berry, R. J., Friedman, J. M., & Erickson, J. D. (2007). Race-ethnicity differences in folic acid intake in women of childbearing age in the United States after folic acid fortification: Findings from the National Health and Nutrition Examination Survey, 2001–2002. American Journal of Clinical Nutrition, 85, 1409–1416.PubMed Yang, Q. H., Carter, H. K., Mulinare, J., Berry, R. J., Friedman, J. M., & Erickson, J. D. (2007). Race-ethnicity differences in folic acid intake in women of childbearing age in the United States after folic acid fortification: Findings from the National Health and Nutrition Examination Survey, 2001–2002. American Journal of Clinical Nutrition, 85, 1409–1416.PubMed
21.
Zurück zum Zitat De Wals, P., Tairou, F., Van Allen, M. I., Uh, S. H., Lowry, R. B., Sibbald, B., et al. (2007). Reduction in neural-tube defects after folic acid fortification in Canada. New England Journal of Medicine, 357, 135–142.PubMedCrossRef De Wals, P., Tairou, F., Van Allen, M. I., Uh, S. H., Lowry, R. B., Sibbald, B., et al. (2007). Reduction in neural-tube defects after folic acid fortification in Canada. New England Journal of Medicine, 357, 135–142.PubMedCrossRef
22.
Zurück zum Zitat Catov, J. M., Bodnar, L. M., Ness, R. B., Markovic, N., & Roberts, J. M. (2007). Association of periconceptional multivitamin use and risk of preterm or small-for-gestational-age births. American Journal of Epidemiology, 166, 296–303.PubMedCrossRef Catov, J. M., Bodnar, L. M., Ness, R. B., Markovic, N., & Roberts, J. M. (2007). Association of periconceptional multivitamin use and risk of preterm or small-for-gestational-age births. American Journal of Epidemiology, 166, 296–303.PubMedCrossRef
23.
Zurück zum Zitat Scholl, T. O., Hediger, M. L., Schall, J. I., Khoo, C. S., & Fischer, R. L. (1996). Dietary and serum folate: Their influence on the outcome of pregnancy. American Journal of Clinical Nutrition, 63, 520–525.PubMed Scholl, T. O., Hediger, M. L., Schall, J. I., Khoo, C. S., & Fischer, R. L. (1996). Dietary and serum folate: Their influence on the outcome of pregnancy. American Journal of Clinical Nutrition, 63, 520–525.PubMed
24.
Zurück zum Zitat Bukowski, R., Malone, F. D., Porter, F. T., Nyberg, D. A., Comstock, C. H., Hankins, G. D., et al. (2009). Preconceptional folate supplementation and the risk of spontaneous preterm birth: A cohort study. PLoS Medicine, 6, e1000061.PubMedCrossRef Bukowski, R., Malone, F. D., Porter, F. T., Nyberg, D. A., Comstock, C. H., Hankins, G. D., et al. (2009). Preconceptional folate supplementation and the risk of spontaneous preterm birth: A cohort study. PLoS Medicine, 6, e1000061.PubMedCrossRef
25.
Zurück zum Zitat Timmermans, S., Jaddoe, V. W., Hofman, A., Steegers-Theunissen, R. P., & Steegers, E. A. (2009). Periconception folic acid supplementation, fetal growth and the risks of low birth weight and preterm birth: The generation R study. The British Journal of Nutrition, 102, 777–785.PubMedCrossRef Timmermans, S., Jaddoe, V. W., Hofman, A., Steegers-Theunissen, R. P., & Steegers, E. A. (2009). Periconception folic acid supplementation, fetal growth and the risks of low birth weight and preterm birth: The generation R study. The British Journal of Nutrition, 102, 777–785.PubMedCrossRef
26.
Zurück zum Zitat Czeizel, A. E. (2009). Periconceptional folic acid and multivitamin supplementation for the prevention of neural tube defects and other congenital abnormalities. Birth Defects Research. Part A, Clinical and Molecular Teratology, 85, 260–268.PubMedCrossRef Czeizel, A. E. (2009). Periconceptional folic acid and multivitamin supplementation for the prevention of neural tube defects and other congenital abnormalities. Birth Defects Research. Part A, Clinical and Molecular Teratology, 85, 260–268.PubMedCrossRef
27.
Zurück zum Zitat Vahratian, A., Siega-Riz, A. M., Savitz, D. A., & Thorp, J. M., Jr. (2004). Multivitamin use and the risk of preterm birth. American Journal of Epidemiology, 160, 886–892.PubMedCrossRef Vahratian, A., Siega-Riz, A. M., Savitz, D. A., & Thorp, J. M., Jr. (2004). Multivitamin use and the risk of preterm birth. American Journal of Epidemiology, 160, 886–892.PubMedCrossRef
28.
Zurück zum Zitat Dowd, J. B., & Aiello, A. E. (2008). Did national folic acid fortification reduce socioeconomic and racial disparities in folate status in the US? International Journal of Epidemiology, 37, 1059–1066.PubMedCrossRef Dowd, J. B., & Aiello, A. E. (2008). Did national folic acid fortification reduce socioeconomic and racial disparities in folate status in the US? International Journal of Epidemiology, 37, 1059–1066.PubMedCrossRef
29.
Zurück zum Zitat Tough, S. C., Clarke, M., Hicks, M., & Cook, J. (2006). Pre-conception practices among family physicians and obstetrician-gynaecologists: Results from a National Survey. Journal of Obstetrics and Gynaecology Canada, 28, 780–788.PubMed Tough, S. C., Clarke, M., Hicks, M., & Cook, J. (2006). Pre-conception practices among family physicians and obstetrician-gynaecologists: Results from a National Survey. Journal of Obstetrics and Gynaecology Canada, 28, 780–788.PubMed
30.
Zurück zum Zitat Morin, P., Demers, K., Giguere, C., Tribble, D. S., & Lane, J. (2007). Multivitamin supplement for primary prevention of birth defects: Application of a preventive clinical practice. Canadian Family Physician, 53, 2142–2143.PubMed Morin, P., Demers, K., Giguere, C., Tribble, D. S., & Lane, J. (2007). Multivitamin supplement for primary prevention of birth defects: Application of a preventive clinical practice. Canadian Family Physician, 53, 2142–2143.PubMed
31.
Zurück zum Zitat Robbins, J. M., Cleves, M. A., Collins, H. B., Andrews, N., Smith, L. N., & Hobbs, C. A. (2005). Randomized trial of a physician-based intervention to increase the use of folic acid supplements among women. American Journal of Obstetrics and Gynecology, 192, 1126–1132.PubMedCrossRef Robbins, J. M., Cleves, M. A., Collins, H. B., Andrews, N., Smith, L. N., & Hobbs, C. A. (2005). Randomized trial of a physician-based intervention to increase the use of folic acid supplements among women. American Journal of Obstetrics and Gynecology, 192, 1126–1132.PubMedCrossRef
35.
Zurück zum Zitat Czeizel, A. E., & Dudas, I. (1992). Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. New England Journal of Medicine, 327, 1832–1835.PubMedCrossRef Czeizel, A. E., & Dudas, I. (1992). Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. New England Journal of Medicine, 327, 1832–1835.PubMedCrossRef
36.
Zurück zum Zitat Mosley, B. S., Cleves, M. A., Siega-Riz, A. M., Shaw, G. M., Canfield, M. A., Waller, D. K., et al. (2009). Neural tube defects and maternal folate intake among pregnancies conceived after folic acid fortification in the United States. American Journal of Epidemiology, 169, 9–17.PubMedCrossRef Mosley, B. S., Cleves, M. A., Siega-Riz, A. M., Shaw, G. M., Canfield, M. A., Waller, D. K., et al. (2009). Neural tube defects and maternal folate intake among pregnancies conceived after folic acid fortification in the United States. American Journal of Epidemiology, 169, 9–17.PubMedCrossRef
Metadaten
Titel
U.S. Provider Reported Folic Acid or Multivitamin Ordering for Non-Pregnant Women of Childbearing Age: NAMCS and NHAMCS, 2005–2006
verfasst von
Heather H. Burris
Martha M. Werler
Publikationsdatum
01.04.2011
Verlag
Springer US
Erschienen in
Maternal and Child Health Journal / Ausgabe 3/2011
Print ISSN: 1092-7875
Elektronische ISSN: 1573-6628
DOI
https://doi.org/10.1007/s10995-010-0587-6

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