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01.02.2011

Impact and characteristics of quality of life in Japanese patients with multiple sclerosis

verfasst von: Hiromi Kikuchi, Nobuhiro Mifune, Masaaki Niino, Sadayoshi Ohbu, Jun-ichi Kira, Tatsuo Kohriyama, Kohei Ota, Masami Tanaka, Hirofumi Ochi, Shunya Nakane, Masaji Maezawa, Seiji Kikuchi

Erschienen in: Quality of Life Research | Ausgabe 1/2011

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Abstract

Purpose

To evaluate health-related quality of life (HRQOL) in Japanese patients with multiple sclerosis (MS) and investigate associations between the results of these QOL assessments and disease severity.

Methods

One-hundred sixty-three Japanese MS patients completed a questionnaire battery comprising the Functional Assessment of MS (FAMS), the Nottingham Adjustment Scale-Japanese version (NAS-J), and the European QOL scale (EQ-5D). Additional five factors affecting QOL as identified by MS patients in a focus group interview were also investigated: employment status, change of income, availability of disease information, communication with medical staff, and care received. Disease severity was determined using the Expanded Disability Status Scale (EDSS).

Results

There was a strong negative correlation of the subscale scores for mobility, symptoms, emotional well-being, thinking and fatigue, and additional concerns on the FAMS with EDSS score. For the NAS-J, only acceptance of the condition was correlated with disease severity. Among the five additional aspects of the condition identified by patients, employment status, income, and disease information were shown to be important for maintaining QOL in patients with MS.

Conclusions

Support for finding employment and having increased or maintained household income and readily available information about the disease contribute to improving QOL in Japanese MS patients.

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Titel: Impact and characteristics of quality of life in Japanese patients with multiple sclerosis
verfasst von: Hiromi Kikuchi
Nobuhiro Mifune
Masaaki Niino
Sadayoshi Ohbu
Jun-ichi Kira
Tatsuo Kohriyama
Kohei Ota
Masami Tanaka
Hirofumi Ochi
Shunya Nakane
Masaji Maezawa
Seiji Kikuchi
Publikationsdatum: 01.02.2011
Verlag: Springer Netherlands
Erschienen in: Quality of Life Research / Ausgabe 1/2011
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-010-9725-2

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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