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01.06.2013

Usefulness of EQ-5D for evaluation of health-related quality of life in young adults with first-episode psychosis

verfasst von: J. Stochl, T. Croudace, J. Perez, M. Birchwood, H. Lester, M. Marshall, T. Amos, V. Sharma, D. Fowler, P. B. Jones, The National Eden Study Team

Erschienen in: Quality of Life Research | Ausgabe 5/2013

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Abstract

Purpose

To evaluate the psychometric properties of the EQ-5D and the usefulness of this instrument in psychiatric practice as a measure of health-related quality of life (HRQoL) in a sample of young adults with first-episode psychosis.

Methods

The validity of individual questionnaire items is studied using an Item Response/Latent Trait Theory modeling approach. Sensitivity of response patterns on EQ-5D items to particular diagnostic subtypes of psychosis is investigated using a finite mixture modeling approach through latent class analysis. Finally, a structural equation modeling framework is used to study differential item functioning via a multigroup approach.

Results

Results suggest that the data closely correspond to the Rasch Rating Scale Model, and therefore that EQ-5D latent scores are equal interval measures. Despite comprising relatively few items, the instrument yields reliable measures of HRQoL for group comparisons and cost-effectiveness evaluation, but EQ-5D score is too imprecise for the assessment of HRQoL for clinical purposes at the individual level. A significant relationship was found between EQ-5D responses and type of psychosis due to inclusion of item anxiety/depression in EQ-5D. Two items (anxiety/depression, functioning in usual activities) showed an ethnicity bias.

Conclusions

Psychometric evidence confirmed the EQ-5D to be a valid, interval measure that is scalable according to Rasch principles.

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Titel: Usefulness of EQ-5D for evaluation of health-related quality of life in young adults with first-episode psychosis
verfasst von: J. Stochl
T. Croudace
J. Perez
M. Birchwood
H. Lester
M. Marshall
T. Amos
V. Sharma
D. Fowler
P. B. Jones
The National Eden Study Team
Publikationsdatum: 01.06.2013
Verlag: Springer Netherlands
Erschienen in: Quality of Life Research / Ausgabe 5/2013
Print ISSN: 0962-9343
Elektronische ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-012-0222-7

Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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