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International Urology and Nephrology

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01.09.2007 | Original Paper

A prospective study of the efficacy of Serenoa repens, Tamsulosin, and Serenoa repens plus Tamsulosin treatment for patients with benign prostate hyperplasia

verfasst von: Fatih Hızlı, M. Cemil Uygur

Erschienen in: International Urology and Nephrology | Ausgabe 3/2007

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Abstract

Introduction

Increasing attention has been focused on the use of phytotherapeutic agents to alleviate the symptoms of benign prostatic hyperplasia (BPH) in recent times. The best described and studied phytotherapeutic agent is Serenoa repens (SR).

Materials and methods

This prospective study was designed to have 3 arms including SR 320 mg per day (N = 20), Tamsulosin (TAM) 0.4 mg per day (N = 20) and SR + TAM (N = 20) to reveal the superiority or equivalence between these treatment regimens in BPH.

Results

The groups were not statistically different with regard to increase in maximal urinary flow rate (Q _max) and decrease in International Prostate Symptom Score (I-PSS) (P > 0.05). No adverse effect was detected in SR therapy group.

Conclusion

Treatment of BPH by both SR and TAM seems to be effective alone. None of them had superiority to another and additionally, combined therapy (SR + TAM) does not provide extra benefits. Furthermore SR is a well-tolerated agent that can be used alternatively in the treatment of LUTS due to BPH.

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Titel: A prospective study of the efficacy of Serenoa repens, Tamsulosin, and Serenoa repens plus Tamsulosin treatment for patients with benign prostate hyperplasia
verfasst von: Fatih Hızlı
M. Cemil Uygur
Publikationsdatum: 01.09.2007
Verlag: Springer Netherlands
Erschienen in: International Urology and Nephrology / Ausgabe 3/2007
Print ISSN: 0301-1623
Elektronische ISSN: 1573-2584
DOI: https://doi.org/10.1007/s11255-006-9106-5

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A prospective study of the efficacy of Serenoa repens, Tamsulosin, and Serenoa repens plus Tamsulosin treatment for patients with benign prostate hyperplasia

Abstract

Introduction

Materials and methods

Results

Conclusion

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Abstract

Introduction

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Conclusion

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