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01.08.2012 | The Therapeutic Trials (G Mancia and TD Giles, Section Editors)

Total Cardiovascular Risk, Blood Pressure Variability and Adrenergic Overdrive in Hypertension: Evidence, Mechanisms and Clinical Implications

verfasst von: Guido Grassi, Michele Bombelli, Gianmaria Brambilla, Fosca Quarti Trevano, Raffaella Dell’Oro, Giuseppe Mancia

Erschienen in: Current Hypertension Reports | Ausgabe 4/2012

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Abstract

In hypertensive patients the risk of developing cardiovascular events and complications depends not only on the magnitude of the blood pressure elevation, but also, and to a consistent extent, on the presence of associated cardiovascular risk factors, concomitant disease and target organ damage. Recent findings suggest that also sympathetic overdrive and alterations in blood pressure variability (which are detected in hypertension) may participate at the increased cardiovascular risk of the patients with high blood pressure. This review will discuss the evidence collected over the past few years on the relationships between sympathetic activation and blood pressure variability and their impact on cardiovascular risk profile.

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Titel: Total Cardiovascular Risk, Blood Pressure Variability and Adrenergic Overdrive in Hypertension: Evidence, Mechanisms and Clinical Implications
verfasst von: Guido Grassi
Michele Bombelli
Gianmaria Brambilla
Fosca Quarti Trevano
Raffaella Dell’Oro
Giuseppe Mancia
Publikationsdatum: 01.08.2012
Verlag: Current Science Inc.
Erschienen in: Current Hypertension Reports / Ausgabe 4/2012
Print ISSN: 1522-6417
Elektronische ISSN: 1534-3111
DOI: https://doi.org/10.1007/s11906-012-0273-8

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