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Erschienen in:

01.06.2013 | Therapeutic Trials (G Mancia, Section Editor)

The Pamela Study: Main Findings and Perspectives

verfasst von: Michele Bombelli, Elena Toso, Maria Peronio, Danilo Fodri, Marco Volpe, Gianmaria Brambilla, Rita Facchetti, Roberto Sega, Guido Grassi, Giuseppe Mancia

Erschienen in: Current Hypertension Reports | Ausgabe 3/2013

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Abstract

PAMELA (Pressioni Arteriose Monitorate E Loro Associazioni) is an epidemiological study, originally designed to determine the normality of home and ambulatory blood pressure values. The study was performed on 3,200 subjects, aged 25 to 74 years, randomly selected from the general population of Monza (Milan, Italy). In the study context we performed clinical, home and ambulatory blood pressure measurements, echocardiographic assessment of cardiac structure and function as well as laboratory examinations (glucose and lipids). Personal and family histories were collected. The same procedures were repeated 10 years later. During a 12-year follow-up, the incident cardiovascular events were validated. Cardiovascular and all-cause fatal events were collected for a 16-year follow-up. This article will review the main results of the PAMELA study, with particular emphasis on (1) the prognostic value of the different blood pressure measurements, (2) the relationships between metabolic variables and blood pressure and (3) the clinical relevance and prognostic importance of left ventricular mass values and alterations.

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Titel: The Pamela Study: Main Findings and Perspectives
verfasst von: Michele Bombelli
Elena Toso
Maria Peronio
Danilo Fodri
Marco Volpe
Gianmaria Brambilla
Rita Facchetti
Roberto Sega
Guido Grassi
Giuseppe Mancia
Publikationsdatum: 01.06.2013
Verlag: Current Science Inc.
Erschienen in: Current Hypertension Reports / Ausgabe 3/2013
Print ISSN: 1522-6417
Elektronische ISSN: 1534-3111
DOI: https://doi.org/10.1007/s11906-013-0348-1

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