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Current Neurology and Neuroscience Reports
Erschienen in: Current Neurology and Neuroscience Reports 5/2010

01.09.2010

What Can We Learn From Freezing of Gait in Parkinson’s Disease?

verfasst von: Nina Browner, Nir Giladi

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 5/2010

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Abstract

Freezing of gait (FOG) is defined as an episodic inability to generate effective stepping in the absence of any known cause, other than parkinsonism or high-level gait disorders. Substantial effort has been made to describe the clinical and kinematic characteristics of patients with FOG. In our review, we highlight the distinctive features of FOG in Parkinson’s disease (PD) and apply the knowledge of its pathophysiology in PD to other clinical situations and conditions. It is possible that FOG in PD represents the ultimate break in the frontal lobe–basal ganglia–cerebellar–brainstem network that controls gait. Dysrhythmic and discoordinated gait with abnormal scaling of stride length, as well as gait festination, likely is the primary and continuous abnormality of “the gait network” in PD, and FOG represents its extreme and complete but transient disruption.
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Metadaten
Titel
What Can We Learn From Freezing of Gait in Parkinson’s Disease?
verfasst von
Nina Browner
Nir Giladi
Publikationsdatum
01.09.2010
Verlag
Current Science Inc.
Erschienen in
Current Neurology and Neuroscience Reports / Ausgabe 5/2010
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-010-0127-1

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