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Current Neurology and Neuroscience Reports
Erschienen in: Current Neurology and Neuroscience Reports 1/2011

01.02.2011

Prognosis After Cardiac Arrest and Hypothermia: A New Paradigm

verfasst von: Edgar A. Samaniego, Suzanne Persoon, Christine A. C. Wijman

Erschienen in: Current Neurology and Neuroscience Reports | Ausgabe 1/2011

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Abstract

Before the use of hypothermia as a treatment for comatose post-cardiac arrest patients, several prognostic variables were widely accepted as reliable and valid for the prediction of poor outcome. Recent studies using hypothermia have reported on patients with recovery of consciousness in spite of absent or extensor motor responses after 3 days, absent bilateral cortical N20 responses after 24 h, serum neuron-specific enolase levels greater than 33 μg/L, and early myoclonus status epilepticus. Hypothermia and its associated use of sedative and paralytic agents may delay neurologic recovery and affect the optimal timing of prognostic variables. Recent developments in brain imaging may provide additional objective prognostic information and deserve further study. Pending the results of future validation studies in patients treated with hypothermia, we recommend that irreversible management decisions not be made based on a single prognostic parameter, and, if there is uncertainty, these decisions be delayed for several days to allow for repeated testing.
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Metadaten
Titel
Prognosis After Cardiac Arrest and Hypothermia: A New Paradigm
verfasst von
Edgar A. Samaniego
Suzanne Persoon
Christine A. C. Wijman
Publikationsdatum
01.02.2011
Verlag
Current Science Inc.
Erschienen in
Current Neurology and Neuroscience Reports / Ausgabe 1/2011
Print ISSN: 1528-4042
Elektronische ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-010-0148-9

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