Skip to main content
Erschienen in: Clinical Orthopaedics and Related Research® 4/2013

01.04.2013 | Symposium: Osteochondritis Dissecans

A Review of Knowledge in Osteochondritis Dissecans: 123 Years of Minimal Evolution from König to the ROCK Study Group

verfasst von: Eric W. Edmonds, MD, John Polousky, MD

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 4/2013

Einloggen, um Zugang zu erhalten

Abstract

Background

Osteochondritis dissecans (OCD) was first described to provide an explanation for the nontraumatic development of loose bodies within a joint. Despite many reports on the subject, there remains no clear understanding of the etiology, natural history, or treatment.

Questions/purposes

This review was undertaken to delineate (1) the etiology of OCD; (2) the presentation and locations; (3) the most appropriate imaging modalities; and (4) the most effective treatment strategies.

Methods

We reviewed the English literature using a database compiled from a Medline search for “osteochondritis dissecans”. We identified 1716 publications, 1246 of which were in English. After exclusions, we reviewed 748 articles and of these cited 85. The observations of each study were then synthesized into this report.

Results

There appears to be no consensus concerning the etiology of OCD lesions. The presentations and locations are variable, but the knee, ankle, and elbow are most commonly involved. Although plain film assessment is important in OCD, there appears to be a trend toward the use of MRI, but the preferred sequences are in evolution. We found no consensus on the treatment of these lesions, related in part to the lack of agreement of methods for assessing outcomes.

Conclusions

Despite more than a century of study, we have made little advancement in our understanding of OCD. A study group has been formed to address this issue and actively seeks to answer these unknown issues regarding OCD.
Literatur
1.
Zurück zum Zitat Aichroth P. Osteochondritis dissecans of the knee. A clinical survey. J Bone Joint Surg Br. 1971;53:440–447.PubMed Aichroth P. Osteochondritis dissecans of the knee. A clinical survey. J Bone Joint Surg Br. 1971;53:440–447.PubMed
2.
Zurück zum Zitat Barrie HJ. Hypertrophy and laminar calcification of cartilage in loose bodies as probable evidence of an ossification abnormality. J Pathol. 1980;132:161–168.PubMedCrossRef Barrie HJ. Hypertrophy and laminar calcification of cartilage in loose bodies as probable evidence of an ossification abnormality. J Pathol. 1980;132:161–168.PubMedCrossRef
3.
Zurück zum Zitat Barrie HJ. Hypothesis—a diagram of the form and origin of loose bodies in osteochondritis dissecans. J Rheumatol. 1984;11:512–513.PubMed Barrie HJ. Hypothesis—a diagram of the form and origin of loose bodies in osteochondritis dissecans. J Rheumatol. 1984;11:512–513.PubMed
4.
Zurück zum Zitat Bedi A, Feeley BT, Williams RJ 3rd. Management of articular cartilage defects of the knee. J Bone Joint Surg Am. 2010;92:994–1009.PubMedCrossRef Bedi A, Feeley BT, Williams RJ 3rd. Management of articular cartilage defects of the knee. J Bone Joint Surg Am. 2010;92:994–1009.PubMedCrossRef
5.
Zurück zum Zitat Bradley J, Dandy DJ. Osteochondritis dissecans and other lesions of the femoral condyles. J Bone Joint Surg Br. 1989;71:518–522.PubMed Bradley J, Dandy DJ. Osteochondritis dissecans and other lesions of the femoral condyles. J Bone Joint Surg Br. 1989;71:518–522.PubMed
6.
Zurück zum Zitat Bradley J, Dandy DJ. Results of drilling osteochondritis dissecans before skeletal maturity. J Bone Joint Surg Br. 1989;71:642–644.PubMed Bradley J, Dandy DJ. Results of drilling osteochondritis dissecans before skeletal maturity. J Bone Joint Surg Br. 1989;71:642–644.PubMed
7.
Zurück zum Zitat Bruns J, Rayf M, Steinhagen J. Longitudinal long-term results of surgical treatment in patients with osteochondritis dissecans of the femoral condyles. Knee Surg Sports Traumatol Arthrosc. 2008;16:436–441.PubMedCrossRef Bruns J, Rayf M, Steinhagen J. Longitudinal long-term results of surgical treatment in patients with osteochondritis dissecans of the femoral condyles. Knee Surg Sports Traumatol Arthrosc. 2008;16:436–441.PubMedCrossRef
8.
Zurück zum Zitat Cahill B. Treatment of juvenile osteochondritis dissecans and osteochondritis dissecans of the knee. Clin Sports Med. 1985;4:367–384.PubMed Cahill B. Treatment of juvenile osteochondritis dissecans and osteochondritis dissecans of the knee. Clin Sports Med. 1985;4:367–384.PubMed
9.
Zurück zum Zitat Cahill BR. Osteochondritis dissecans of the knee: treatment of juvenile and adult forms. J Am Acad Orthop Surg. 1995;3:237–247.PubMed Cahill BR. Osteochondritis dissecans of the knee: treatment of juvenile and adult forms. J Am Acad Orthop Surg. 1995;3:237–247.PubMed
10.
Zurück zum Zitat Cahill BR, Ahten SM. The three critical components in the conservative treatment of juvenile osteochondritis dissecans (JOCD). Physician, parent, and child. Clin Sports Med. 2001;20:287–298, vi.PubMedCrossRef Cahill BR, Ahten SM. The three critical components in the conservative treatment of juvenile osteochondritis dissecans (JOCD). Physician, parent, and child. Clin Sports Med. 2001;20:287–298, vi.PubMedCrossRef
11.
Zurück zum Zitat Cahill BR, Phillips MR, Navarro R. The results of conservative management of juvenile osteochondritis dissecans using joint scintigraphy. A prospective study. Am J Sports Med. 1989;17:601–605; discussion 605–606.PubMedCrossRef Cahill BR, Phillips MR, Navarro R. The results of conservative management of juvenile osteochondritis dissecans using joint scintigraphy. A prospective study. Am J Sports Med. 1989;17:601–605; discussion 605–606.PubMedCrossRef
12.
Zurück zum Zitat Chambers HG, Shea KG, Carey JL. AAOS Clinical Practice Guideline: diagnosis and treatment of osteochondritis dissecans. J Am Acad Orthop Surg. 2011;19:307–309.PubMed Chambers HG, Shea KG, Carey JL. AAOS Clinical Practice Guideline: diagnosis and treatment of osteochondritis dissecans. J Am Acad Orthop Surg. 2011;19:307–309.PubMed
13.
Zurück zum Zitat Chiroff RT, Cooke CP 3rd. Osteochondritis dissecans: a histologic and microradiographic analysis of surgically excised lesions. J Trauma. 1975;15:689–696.PubMedCrossRef Chiroff RT, Cooke CP 3rd. Osteochondritis dissecans: a histologic and microradiographic analysis of surgically excised lesions. J Trauma. 1975;15:689–696.PubMedCrossRef
14.
Zurück zum Zitat Crawford DC, Safran MR. Osteochondritis dissecans of the knee. J Am Acad Orthop Surg. 2006;14:90–100.PubMed Crawford DC, Safran MR. Osteochondritis dissecans of the knee. J Am Acad Orthop Surg. 2006;14:90–100.PubMed
15.
Zurück zum Zitat De Smet AA, Fisher DR, Graf BK, Lange RH. Osteochondritis dissecans of the knee: value of MR imaging in determining lesion stability and the presence of articular cartilage defects. AJR Am J Roentgenol. 1990;155:549–553.PubMedCrossRef De Smet AA, Fisher DR, Graf BK, Lange RH. Osteochondritis dissecans of the knee: value of MR imaging in determining lesion stability and the presence of articular cartilage defects. AJR Am J Roentgenol. 1990;155:549–553.PubMedCrossRef
16.
Zurück zum Zitat De Smet AA, Ilahi OA, Graf BK. Reassessment of the MR criteria for stability of osteochondritis dissecans in the knee and ankle. Skeletal Radiol. 1996;25:159–163.PubMedCrossRef De Smet AA, Ilahi OA, Graf BK. Reassessment of the MR criteria for stability of osteochondritis dissecans in the knee and ankle. Skeletal Radiol. 1996;25:159–163.PubMedCrossRef
17.
Zurück zum Zitat Edmonds EW, Albright J, Bastrom T, Chambers HG. Outcomes of extra-articular, intra-epiphyseal drilling for osteochondritis dissecans of the knee. J Pediatr Orthop. 2010;30:870–878.PubMedCrossRef Edmonds EW, Albright J, Bastrom T, Chambers HG. Outcomes of extra-articular, intra-epiphyseal drilling for osteochondritis dissecans of the knee. J Pediatr Orthop. 2010;30:870–878.PubMedCrossRef
18.
Zurück zum Zitat Emmerson BC, Gortz S, Jamali AA, Chung C, Amiel D, Bugbee WD. Fresh osteochondral allografting in the treatment of osteochondritis dissecans of the femoral condyle. Am J Sports Med. 2007;35:907–914.PubMedCrossRef Emmerson BC, Gortz S, Jamali AA, Chung C, Amiel D, Bugbee WD. Fresh osteochondral allografting in the treatment of osteochondritis dissecans of the femoral condyle. Am J Sports Med. 2007;35:907–914.PubMedCrossRef
19.
20.
Zurück zum Zitat Fonseca F, Balaco I. Fixation with autogenous osteochondral grafts for the treatment of osteochondritis dissecans (stages III and IV). Int Orthop. 2009;33:139–144.PubMedCrossRef Fonseca F, Balaco I. Fixation with autogenous osteochondral grafts for the treatment of osteochondritis dissecans (stages III and IV). Int Orthop. 2009;33:139–144.PubMedCrossRef
21.
Zurück zum Zitat Freifberg AH, Woolley PG. Osteochondritis dissecans: concerning its nature and relation to formation of joint mice. J Bone Joint Surg Am. 1910; s2–s8: 477–494. Freifberg AH, Woolley PG. Osteochondritis dissecans: concerning its nature and relation to formation of joint mice. J Bone Joint Surg Am. 1910; s2–s8: 477–494.
22.
Zurück zum Zitat Friederichs MG, Greis PE, Burks RT. Pitfalls associated with fixation of osteochondritis dissecans fragments using bioabsorbable screws. Arthroscopy. 2001;17:542–545.PubMedCrossRef Friederichs MG, Greis PE, Burks RT. Pitfalls associated with fixation of osteochondritis dissecans fragments using bioabsorbable screws. Arthroscopy. 2001;17:542–545.PubMedCrossRef
23.
Zurück zum Zitat Garrett JC. Fresh osteochondral allografts for treatment of articular defects in osteochondritis dissecans of the lateral femoral condyle in adults. Clin Orthop Relat Res. 1994;303:33–37.PubMed Garrett JC. Fresh osteochondral allografts for treatment of articular defects in osteochondritis dissecans of the lateral femoral condyle in adults. Clin Orthop Relat Res. 1994;303:33–37.PubMed
24.
Zurück zum Zitat Gebarski K, Hernandez RJ. Stage-I osteochondritis dissecans versus normal variants of ossification in the knee in children. Pediatr Radiol. 2005;35:880–886.PubMedCrossRef Gebarski K, Hernandez RJ. Stage-I osteochondritis dissecans versus normal variants of ossification in the knee in children. Pediatr Radiol. 2005;35:880–886.PubMedCrossRef
25.
Zurück zum Zitat Ghazavi MT, Pritzker KP, Davis AM, Gross AE. Fresh osteochondral allografts for post-traumatic osteochondral defects of the knee. J Bone Joint Surg Br. 1997;79:1008–1013.PubMedCrossRef Ghazavi MT, Pritzker KP, Davis AM, Gross AE. Fresh osteochondral allografts for post-traumatic osteochondral defects of the knee. J Bone Joint Surg Br. 1997;79:1008–1013.PubMedCrossRef
26.
Zurück zum Zitat Glancy GL. Juvenile osteochondritis dissecans. Am J Knee Surg. 1999;12:120–124.PubMed Glancy GL. Juvenile osteochondritis dissecans. Am J Knee Surg. 1999;12:120–124.PubMed
27.
Zurück zum Zitat Gomoll AH, Flik KR, Hayden JK, Cole BJ, Bush-Joseph CA, Bach BR Jr. Internal fixation of unstable Cahill Type-2C osteochondritis dissecans lesions of the knee in adolescent patients. Orthopedics. 2007;30:487–490.PubMed Gomoll AH, Flik KR, Hayden JK, Cole BJ, Bush-Joseph CA, Bach BR Jr. Internal fixation of unstable Cahill Type-2C osteochondritis dissecans lesions of the knee in adolescent patients. Orthopedics. 2007;30:487–490.PubMed
28.
Zurück zum Zitat Green WT, Banks HH. Osteochondritis dissecans in children. J Bone Joint Surg Am. 1953;35:26–47; passim.PubMed Green WT, Banks HH. Osteochondritis dissecans in children. J Bone Joint Surg Am. 1953;35:26–47; passim.PubMed
29.
Zurück zum Zitat Gudas R, Simonaityte R, Cekanauskas E, Tamosiunas R. A prospective, randomized clinical study of osteochondral autologous transplantation versus microfracture for the treatment of osteochondritis dissecans in the knee joint in children. J Pediatr Orthop. 2009;29:741–748.PubMedCrossRef Gudas R, Simonaityte R, Cekanauskas E, Tamosiunas R. A prospective, randomized clinical study of osteochondral autologous transplantation versus microfracture for the treatment of osteochondritis dissecans in the knee joint in children. J Pediatr Orthop. 2009;29:741–748.PubMedCrossRef
30.
Zurück zum Zitat Guhl JF. Arthroscopic treatment of osteochondritis dissecans. Clin Orthop Relat Res. 1982;167:65–74.PubMed Guhl JF. Arthroscopic treatment of osteochondritis dissecans. Clin Orthop Relat Res. 1982;167:65–74.PubMed
31.
Zurück zum Zitat Hefti F, Beguiristain J, Krauspe R, Moller-Madsen B, Riccio V, Tschauner C, Wetzel R, Zeller R. Osteochondritis dissecans: a multicenter study of the European Pediatric Orthopedic Society. J Pediatr Orthop B. 1999;8:231–245.PubMed Hefti F, Beguiristain J, Krauspe R, Moller-Madsen B, Riccio V, Tschauner C, Wetzel R, Zeller R. Osteochondritis dissecans: a multicenter study of the European Pediatric Orthopedic Society. J Pediatr Orthop B. 1999;8:231–245.PubMed
32.
Zurück zum Zitat Hughston JC, Hergenroeder PT, Courtenay BG. Osteochondritis dissecans of the femoral condyles. J Bone Joint Surg Am. 1984;66:1340–1348.PubMed Hughston JC, Hergenroeder PT, Courtenay BG. Osteochondritis dissecans of the femoral condyles. J Bone Joint Surg Am. 1984;66:1340–1348.PubMed
33.
Zurück zum Zitat Jacobi M, Wahl P, Bouaicha S, Jakob RP, Gautier E. Association between mechanical axis of the leg and osteochondritis dissecans of the knee: radiographic study on 103 knees. Am J Sports Med. 2010;38:1425–1428.PubMedCrossRef Jacobi M, Wahl P, Bouaicha S, Jakob RP, Gautier E. Association between mechanical axis of the leg and osteochondritis dissecans of the knee: radiographic study on 103 knees. Am J Sports Med. 2010;38:1425–1428.PubMedCrossRef
34.
Zurück zum Zitat Johnson LL, Uitvlugt G, Austin MD, Detrisac DA, Johnson C. Osteochondritis dissecans of the knee: arthroscopic compression screw fixation. Arthroscopy. 1990;6:179–189.PubMedCrossRef Johnson LL, Uitvlugt G, Austin MD, Detrisac DA, Johnson C. Osteochondritis dissecans of the knee: arthroscopic compression screw fixation. Arthroscopy. 1990;6:179–189.PubMedCrossRef
35.
Zurück zum Zitat Jurgensen I, Bachmann G, Schleicher I, Haas H. Arthroscopic versus conservative treatment of osteochondritis dissecans of the knee: value of magnetic resonance imaging in therapy planning and follow-up. Arthroscopy. 2002;18:378–386.PubMedCrossRef Jurgensen I, Bachmann G, Schleicher I, Haas H. Arthroscopic versus conservative treatment of osteochondritis dissecans of the knee: value of magnetic resonance imaging in therapy planning and follow-up. Arthroscopy. 2002;18:378–386.PubMedCrossRef
36.
Zurück zum Zitat Kijowski R, Blankenbaker DG, Shinki K, Fine JP, Graf BK, De Smet AA. Juvenile versus adult osteochondritis dissecans of the knee: appropriate MR imaging criteria for instability. Radiology. 2008;248:571–578.PubMedCrossRef Kijowski R, Blankenbaker DG, Shinki K, Fine JP, Graf BK, De Smet AA. Juvenile versus adult osteochondritis dissecans of the knee: appropriate MR imaging criteria for instability. Radiology. 2008;248:571–578.PubMedCrossRef
37.
Zurück zum Zitat Kivisto R, Pasanen L, Leppilahti J, Jalovaara P. Arthroscopic repair of osteochondritis dissecans of the femoral condyles with metal staple fixation: a report of 28 cases. Knee Surg Sports Traumatol Arthrosc. 2002;10:305–309.PubMed Kivisto R, Pasanen L, Leppilahti J, Jalovaara P. Arthroscopic repair of osteochondritis dissecans of the femoral condyles with metal staple fixation: a report of 28 cases. Knee Surg Sports Traumatol Arthrosc. 2002;10:305–309.PubMed
38.
Zurück zum Zitat Kobayashi T, Fujikawa K, Oohashi M. Surgical fixation of massive osteochondritis dissecans lesion using cylindrical osteochondral plugs. Arthroscopy. 2004;20:981–986.PubMed Kobayashi T, Fujikawa K, Oohashi M. Surgical fixation of massive osteochondritis dissecans lesion using cylindrical osteochondral plugs. Arthroscopy. 2004;20:981–986.PubMed
39.
Zurück zum Zitat Kocher MS, Micheli LJ, Yaniv M, Zurakowski D, Ames A, Adrignolo AA. Functional and radiographic outcome of juvenile osteochondritis dissecans of the knee treated with transarticular arthroscopic drilling. Am J Sports Med. 2001;29:562–566.PubMed Kocher MS, Micheli LJ, Yaniv M, Zurakowski D, Ames A, Adrignolo AA. Functional and radiographic outcome of juvenile osteochondritis dissecans of the knee treated with transarticular arthroscopic drilling. Am J Sports Med. 2001;29:562–566.PubMed
40.
Zurück zum Zitat Kocher MS, Tucker R, Ganley TJ, Flynn JM. Management of osteochondritis dissecans of the knee: current concepts review. Am J Sports Med. 2006;34:1181–1191.PubMedCrossRef Kocher MS, Tucker R, Ganley TJ, Flynn JM. Management of osteochondritis dissecans of the knee: current concepts review. Am J Sports Med. 2006;34:1181–1191.PubMedCrossRef
41.
Zurück zum Zitat Konig F. Ueber freie korper in den gelenken. Dtsch Z Chir. 1887;27:90–109.CrossRef Konig F. Ueber freie korper in den gelenken. Dtsch Z Chir. 1887;27:90–109.CrossRef
42.
Zurück zum Zitat Kouzelis A, Plessas S, Papadopoulos AX, Gliatis I, Lambiris E. Herbert screw fixation and reverse guided drillings, for treatment of types III and IV osteochondritis dissecans. Knee Surg Sports Traumatol Arthrosc. 2006;14:70–75.PubMedCrossRef Kouzelis A, Plessas S, Papadopoulos AX, Gliatis I, Lambiris E. Herbert screw fixation and reverse guided drillings, for treatment of types III and IV osteochondritis dissecans. Knee Surg Sports Traumatol Arthrosc. 2006;14:70–75.PubMedCrossRef
43.
Zurück zum Zitat Kozlowski K, Middleton R. Familial osteochondritis dissecans: a dysplasia of articular cartilage? Skeletal Radiol. 1985;13:207–210.PubMedCrossRef Kozlowski K, Middleton R. Familial osteochondritis dissecans: a dysplasia of articular cartilage? Skeletal Radiol. 1985;13:207–210.PubMedCrossRef
44.
Zurück zum Zitat Larsen MW, Pietrzak WS, DeLee JC. Fixation of osteochondritis dissecans lesions using poly(L-lactic acid)/poly(glycolic acid) copolymer bioabsorbable screws. Am J Sports Med. 2005;33:68–76.PubMedCrossRef Larsen MW, Pietrzak WS, DeLee JC. Fixation of osteochondritis dissecans lesions using poly(L-lactic acid)/poly(glycolic acid) copolymer bioabsorbable screws. Am J Sports Med. 2005;33:68–76.PubMedCrossRef
45.
Zurück zum Zitat Lebolt JR, Wall EJ. Retroarticular drilling and bone grafting of juvenile osteochondritis dissecans of the knee. Arthroscopy. 2007;23:794.e1–e4. Lebolt JR, Wall EJ. Retroarticular drilling and bone grafting of juvenile osteochondritis dissecans of the knee. Arthroscopy. 2007;23:794.e1–e4.
46.
Zurück zum Zitat Lee CK, Mercurio C. Operative treatment of osteochondritis dissecans in situ by retrograde drilling and cancellous bone graft: a preliminary report. Clin Orthop Relat Res. 1981;158:129–136.PubMed Lee CK, Mercurio C. Operative treatment of osteochondritis dissecans in situ by retrograde drilling and cancellous bone graft: a preliminary report. Clin Orthop Relat Res. 1981;158:129–136.PubMed
47.
Zurück zum Zitat Linden B. The incidence of osteochondritis dissecans in the condyles of the femur. Acta Orthop Scand. 1976;47:664–667.PubMedCrossRef Linden B. The incidence of osteochondritis dissecans in the condyles of the femur. Acta Orthop Scand. 1976;47:664–667.PubMedCrossRef
48.
Zurück zum Zitat Linden B. Osteochondritis dissecans of the femoral condyles: a long-term follow-up study. J Bone Joint Surg Am. 1977;59:769–776.PubMed Linden B. Osteochondritis dissecans of the femoral condyles: a long-term follow-up study. J Bone Joint Surg Am. 1977;59:769–776.PubMed
49.
Zurück zum Zitat Lindholm TS, Osterman K. Treatment of juvenile osteochondritis dissecans in the knee. Acta Orthop Belg. 1979;45:633–640.PubMed Lindholm TS, Osterman K. Treatment of juvenile osteochondritis dissecans in the knee. Acta Orthop Belg. 1979;45:633–640.PubMed
50.
Zurück zum Zitat Litchman HM, McCullough RW, Gandsman EJ, Schatz SL. Computerized blood flow analysis for decision making in the treatment of osteochondritis dissecans. J Pediatr Orthop. 1988;8:208–212.PubMed Litchman HM, McCullough RW, Gandsman EJ, Schatz SL. Computerized blood flow analysis for decision making in the treatment of osteochondritis dissecans. J Pediatr Orthop. 1988;8:208–212.PubMed
51.
Zurück zum Zitat Mackie IG, Pemberton DJ, Maheson M. Arthroscopic use of the Herbert screw in osteochondritis dissecans. J Bone Joint Surg Br. 1990;72:1076.PubMed Mackie IG, Pemberton DJ, Maheson M. Arthroscopic use of the Herbert screw in osteochondritis dissecans. J Bone Joint Surg Br. 1990;72:1076.PubMed
52.
Zurück zum Zitat Makino A, Muscolo DL, Puigdevall M, Costa-Paz M, Ayerza M. Arthroscopic fixation of osteochondritis dissecans of the knee: clinical, magnetic resonance imaging, and arthroscopic follow-up. Am J Sports Med. 2005;33:1499–1504.PubMedCrossRef Makino A, Muscolo DL, Puigdevall M, Costa-Paz M, Ayerza M. Arthroscopic fixation of osteochondritis dissecans of the knee: clinical, magnetic resonance imaging, and arthroscopic follow-up. Am J Sports Med. 2005;33:1499–1504.PubMedCrossRef
53.
Zurück zum Zitat Michael JW, Wurth A, Eysel P, Konig DP. Long-term results after operative treatment of osteochondritis dissecans of the knee joint-30 year results. Int Orthop. 2008;32:217–221.PubMedCrossRef Michael JW, Wurth A, Eysel P, Konig DP. Long-term results after operative treatment of osteochondritis dissecans of the knee joint-30 year results. Int Orthop. 2008;32:217–221.PubMedCrossRef
54.
Zurück zum Zitat Milgram JW. Radiological and pathological manifestations of osteochondritis dissecans of the distal femur. A study of 50 cases. Radiology. 1978;126:305–311.PubMed Milgram JW. Radiological and pathological manifestations of osteochondritis dissecans of the distal femur. A study of 50 cases. Radiology. 1978;126:305–311.PubMed
55.
Zurück zum Zitat Miniaci A, Tytherleigh-Strong G. Fixation of unstable osteochondritis dissecans lesions of the knee using arthroscopic autogenous osteochondral grafting (mosaicplasty). Arthroscopy. 2007;23:845–851.PubMedCrossRef Miniaci A, Tytherleigh-Strong G. Fixation of unstable osteochondritis dissecans lesions of the knee using arthroscopic autogenous osteochondral grafting (mosaicplasty). Arthroscopy. 2007;23:845–851.PubMedCrossRef
56.
Zurück zum Zitat Mitsuoka T, Shino K, Hamada M, Horibe S. Osteochondritis dissecans of the lateral femoral condyle of the knee joint. Arthroscopy. 1999;15:20–26.PubMedCrossRef Mitsuoka T, Shino K, Hamada M, Horibe S. Osteochondritis dissecans of the lateral femoral condyle of the knee joint. Arthroscopy. 1999;15:20–26.PubMedCrossRef
57.
Zurück zum Zitat Miura K, Ishibashi Y, Tsuda E, Sato H, Toh S. Results of arthroscopic fixation of osteochondritis dissecans lesion of the knee with cylindrical autogenous osteochondral plugs. Am J Sports Med. 2007;35:216–222.PubMedCrossRef Miura K, Ishibashi Y, Tsuda E, Sato H, Toh S. Results of arthroscopic fixation of osteochondritis dissecans lesion of the knee with cylindrical autogenous osteochondral plugs. Am J Sports Med. 2007;35:216–222.PubMedCrossRef
58.
Zurück zum Zitat Mubarak SJ, Carroll NC. Familial osteochondritis dissecans of the knee. Clin Orthop Relat Res. 1979;140:131–136.PubMed Mubarak SJ, Carroll NC. Familial osteochondritis dissecans of the knee. Clin Orthop Relat Res. 1979;140:131–136.PubMed
59.
Zurück zum Zitat Mubarak SJ, Carroll NC. Juvenile osteochondritis dissecans of the knee: etiology. Clin Orthop Relat Res. 1981;157:200–211.PubMed Mubarak SJ, Carroll NC. Juvenile osteochondritis dissecans of the knee: etiology. Clin Orthop Relat Res. 1981;157:200–211.PubMed
60.
Zurück zum Zitat Murray JR, Chitnavis J, Dixon P, Hogan NA, Parker G, Parish EN, Cross MJ. Osteochondritis dissecans of the knee; long-term clinical outcome following arthroscopic débridement. Knee. 2007;14:94–98.PubMedCrossRef Murray JR, Chitnavis J, Dixon P, Hogan NA, Parker G, Parish EN, Cross MJ. Osteochondritis dissecans of the knee; long-term clinical outcome following arthroscopic débridement. Knee. 2007;14:94–98.PubMedCrossRef
61.
Zurück zum Zitat Nakagawa T, Kurosawa H, Ikeda H, Nozawa M, Kawakami A. Internal fixation for osteochondritis dissecans of the knee. Knee Surg Sports Traumatol Arthrosc. 2005;13:317–322.PubMedCrossRef Nakagawa T, Kurosawa H, Ikeda H, Nozawa M, Kawakami A. Internal fixation for osteochondritis dissecans of the knee. Knee Surg Sports Traumatol Arthrosc. 2005;13:317–322.PubMedCrossRef
62.
Zurück zum Zitat Nawata K, Teshima R, Morio Y, Hagino H. Anomalies of ossification in the posterolateral femoral condyle: assessment by MRI. Pediatr Radiol. 1999;29:781–784.PubMedCrossRef Nawata K, Teshima R, Morio Y, Hagino H. Anomalies of ossification in the posterolateral femoral condyle: assessment by MRI. Pediatr Radiol. 1999;29:781–784.PubMedCrossRef
63.
Zurück zum Zitat O’Connor MA, Palaniappan M, Khan N, Bruce CE. Osteochondritis dissecans of the knee in children. A comparison of MRI and arthroscopic findings. J Bone Joint Surg Br. 2002;84:258–262.PubMedCrossRef O’Connor MA, Palaniappan M, Khan N, Bruce CE. Osteochondritis dissecans of the knee in children. A comparison of MRI and arthroscopic findings. J Bone Joint Surg Br. 2002;84:258–262.PubMedCrossRef
64.
Zurück zum Zitat Paget J. On the production of some of the loose bodies in joints. St Bartholomew’s Hospital Reports. 1870;6:1–4. Paget J. On the production of some of the loose bodies in joints. St Bartholomew’s Hospital Reports. 1870;6:1–4.
65.
Zurück zum Zitat Paletta GA Jr, Bednarz PA, Stanitski CL, Sandman GA, Stanitski DF, Kottamasu S. The prognostic value of quantitative bone scan in knee osteochondritis dissecans. A preliminary experience. Am J Sports Med. 1998;26:7–14.PubMed Paletta GA Jr, Bednarz PA, Stanitski CL, Sandman GA, Stanitski DF, Kottamasu S. The prognostic value of quantitative bone scan in knee osteochondritis dissecans. A preliminary experience. Am J Sports Med. 1998;26:7–14.PubMed
66.
Zurück zum Zitat Peterson L, Minas T, Brittberg M, Lindahl A. Treatment of osteochondritis dissecans of the knee with autologous chondrocyte transplantation: results at two to ten years. J Bone Joint Surg Am. 2003;85(Suppl 2):17–24.PubMed Peterson L, Minas T, Brittberg M, Lindahl A. Treatment of osteochondritis dissecans of the knee with autologous chondrocyte transplantation: results at two to ten years. J Bone Joint Surg Am. 2003;85(Suppl 2):17–24.PubMed
67.
Zurück zum Zitat Petrie PW. Aetiology of osteochondritis dissecans. Failure to establish a familial background. J Bone Joint Surg Br. 1977;59:366–367.PubMed Petrie PW. Aetiology of osteochondritis dissecans. Failure to establish a familial background. J Bone Joint Surg Br. 1977;59:366–367.PubMed
68.
Zurück zum Zitat Phillips HO, Grubb SA. Familial multiple osteochondritis dissecans. Report of a kindred. J Bone Joint Surg Am. 1985;67:155–156.PubMed Phillips HO, Grubb SA. Familial multiple osteochondritis dissecans. Report of a kindred. J Bone Joint Surg Am. 1985;67:155–156.PubMed
69.
Zurück zum Zitat Ribbing S. Studies on hereditary, multiple epiphyseal disorder. Acta Radiol. 1937;34:1–107. Ribbing S. Studies on hereditary, multiple epiphyseal disorder. Acta Radiol. 1937;34:1–107.
70.
Zurück zum Zitat Schenck RC Jr, Goodnight JM. Osteochondritis dissecans. J Bone Joint Surg Am. 1996;78:439–456.PubMed Schenck RC Jr, Goodnight JM. Osteochondritis dissecans. J Bone Joint Surg Am. 1996;78:439–456.PubMed
71.
Zurück zum Zitat Slawski DP. High tibial osteotomy in the treatment of adult osteochondritis dissecans. Clin Orthop Relat Res. 1997;341:155–161.PubMedCrossRef Slawski DP. High tibial osteotomy in the treatment of adult osteochondritis dissecans. Clin Orthop Relat Res. 1997;341:155–161.PubMedCrossRef
72.
Zurück zum Zitat Slough JA, Noto AM, Schmidt TL. Tibial cortical bone peg fixation in osteochondritis dissecans of the knee. Clin Orthop Relat Res. 1991;267:122–127.PubMed Slough JA, Noto AM, Schmidt TL. Tibial cortical bone peg fixation in osteochondritis dissecans of the knee. Clin Orthop Relat Res. 1991;267:122–127.PubMed
73.
Zurück zum Zitat Smith DS, Sharp DC, Resendes M. MRI of healing osteochondritis dissecans fragment with absorbable pins. J Comput Assist Tomogr. 1994;18:832–833.PubMedCrossRef Smith DS, Sharp DC, Resendes M. MRI of healing osteochondritis dissecans fragment with absorbable pins. J Comput Assist Tomogr. 1994;18:832–833.PubMedCrossRef
74.
Zurück zum Zitat Stanitski CL, Bee J. Juvenile osteochondritis dissecans of the lateral femoral condyle after lateral discoid meniscal surgery. Am J Sports Med. 2004;32:797–801.PubMedCrossRef Stanitski CL, Bee J. Juvenile osteochondritis dissecans of the lateral femoral condyle after lateral discoid meniscal surgery. Am J Sports Med. 2004;32:797–801.PubMedCrossRef
75.
Zurück zum Zitat Steinhagen J, Bruns J, Deuretzbacher G, Ruether W, Fuerst M, Niggemeyer O. Treatment of osteochondritis dissecans of the femoral condyle with autologous bone grafts and matrix-supported autologous chondrocytes. Int Orthop. 2010;34:819–825.PubMedCrossRef Steinhagen J, Bruns J, Deuretzbacher G, Ruether W, Fuerst M, Niggemeyer O. Treatment of osteochondritis dissecans of the femoral condyle with autologous bone grafts and matrix-supported autologous chondrocytes. Int Orthop. 2010;34:819–825.PubMedCrossRef
76.
Zurück zum Zitat Tabaddor RR, Banffy MB, Andersen JS, McFeely E, Ogunwole O, Micheli LJ, Kocher MS. Fixation of juvenile osteochondritis dissecans lesions of the knee using poly 96L/4D-lactide copolymer bioabsorbable implants. J Pediatr Orthop. 2010;30:14–20.PubMedCrossRef Tabaddor RR, Banffy MB, Andersen JS, McFeely E, Ogunwole O, Micheli LJ, Kocher MS. Fixation of juvenile osteochondritis dissecans lesions of the knee using poly 96L/4D-lactide copolymer bioabsorbable implants. J Pediatr Orthop. 2010;30:14–20.PubMedCrossRef
77.
Zurück zum Zitat Thomson NL. Osteochondritis dissecans and osteochondral fragments managed by Herbert compression screw fixation. Clin Orthop Relat Res. 1987;224:71–78.PubMed Thomson NL. Osteochondritis dissecans and osteochondral fragments managed by Herbert compression screw fixation. Clin Orthop Relat Res. 1987;224:71–78.PubMed
78.
Zurück zum Zitat Uozumi H, Sugita T, Aizawa T, Takahashi A, Ohnuma M, Itoi E. Histologic findings and possible causes of osteochondritis dissecans of the knee. Am J Sports Med. 2009;37:2003–2008.PubMedCrossRef Uozumi H, Sugita T, Aizawa T, Takahashi A, Ohnuma M, Itoi E. Histologic findings and possible causes of osteochondritis dissecans of the knee. Am J Sports Med. 2009;37:2003–2008.PubMedCrossRef
79.
Zurück zum Zitat Wall E, Von Stein D. Juvenile osteochondritis dissecans. Orthop Clin North Am. 2003;34:341–353.PubMedCrossRef Wall E, Von Stein D. Juvenile osteochondritis dissecans. Orthop Clin North Am. 2003;34:341–353.PubMedCrossRef
80.
Zurück zum Zitat Wall EJ, Vourazeris J, Myer GD, Emery KH, Divine JG, Nick TG, Hewett TE. The healing potential of stable juvenile osteochondritis dissecans knee lesions. J Bone Joint Surg Am. 2008;90:2655–2664.PubMedCrossRef Wall EJ, Vourazeris J, Myer GD, Emery KH, Divine JG, Nick TG, Hewett TE. The healing potential of stable juvenile osteochondritis dissecans knee lesions. J Bone Joint Surg Am. 2008;90:2655–2664.PubMedCrossRef
81.
Zurück zum Zitat Wilson JN. A diagnostic sign in osteochondritis dissecans of the knee. J Bone Joint Surg Am. 1967;49:477–480.PubMed Wilson JN. A diagnostic sign in osteochondritis dissecans of the knee. J Bone Joint Surg Am. 1967;49:477–480.PubMed
82.
Zurück zum Zitat Woods K, Harris I. Osteochondritis dissecans of the talus in identical twins. J Bone Joint Surg Br. 1995;77:331.PubMed Woods K, Harris I. Osteochondritis dissecans of the talus in identical twins. J Bone Joint Surg Br. 1995;77:331.PubMed
83.
Zurück zum Zitat Wright RW, McLean M, Matava MJ, Shively RA. Osteochondritis dissecans of the knee: long-term results of excision of the fragment. Clin Orthop Relat Res. 2004;424:239–243.PubMedCrossRef Wright RW, McLean M, Matava MJ, Shively RA. Osteochondritis dissecans of the knee: long-term results of excision of the fragment. Clin Orthop Relat Res. 2004;424:239–243.PubMedCrossRef
84.
Zurück zum Zitat Yonetani Y, Nakamura N, Natsuume T, Shiozaki Y, Tanaka Y, Horibe S. Histological evaluation of juvenile osteochondritis dissecans of the knee: a case series. Knee Surg Sports Traumatol Arthrosc. 2010;18:723–730.PubMedCrossRef Yonetani Y, Nakamura N, Natsuume T, Shiozaki Y, Tanaka Y, Horibe S. Histological evaluation of juvenile osteochondritis dissecans of the knee: a case series. Knee Surg Sports Traumatol Arthrosc. 2010;18:723–730.PubMedCrossRef
85.
Zurück zum Zitat Yoshida S, Ikata T, Takai H, Kashiwaguchi S, Katoh S, Takeda Y. Osteochondritis dissecans of the femoral condyle in the growth stage. Clin Orthop Relat Res. 1998;346:162–170.PubMedCrossRef Yoshida S, Ikata T, Takai H, Kashiwaguchi S, Katoh S, Takeda Y. Osteochondritis dissecans of the femoral condyle in the growth stage. Clin Orthop Relat Res. 1998;346:162–170.PubMedCrossRef
Metadaten
Titel
A Review of Knowledge in Osteochondritis Dissecans: 123 Years of Minimal Evolution from König to the ROCK Study Group
verfasst von
Eric W. Edmonds, MD
John Polousky, MD
Publikationsdatum
01.04.2013
Verlag
Springer-Verlag
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 4/2013
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-012-2290-y

Weitere Artikel der Ausgabe 4/2013

Clinical Orthopaedics and Related Research® 4/2013 Zur Ausgabe

Symposium: Childhood Obesity and Musculoskeletal Problems

Get Up, Get Out, Get Moving: An Interactive Tool for Education at Your Local School

Symposium: Osteochondritis Dissecans

Biographical Sketch: Franz König, MD 1832–1910

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.