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Endocrine

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29.02.2016 | Editorial

Treatment of hypothyroidism: all that glitters is gold?

verfasst von: Anna Maria Formenti, Gherardo Mazziotti, Raffaele Giubbini, Andrea Giustina

Erschienen in: Endocrine | Ausgabe 3/2016

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Excerpt

Levothyroxine (L-T4) is recommended worldwide for replacement therapy of hypothyroidism due to its efficacy in resolving the symptoms, long-term experience of its benefits, long serum half-life, and low cost. Since the isolation of L-T4 by Kendall in 1914 [1] and then the synthesis of T4 and its better absorbed sodium salt [2], it has become the therapy of choice, also due to the demonstration that about 80 % of biologically active tri-iodiothyronine is derived from peripheral conversion of T4 [3]. …

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Titel: Treatment of hypothyroidism: all that glitters is gold?
verfasst von: Anna Maria Formenti
Gherardo Mazziotti
Raffaele Giubbini
Andrea Giustina
Publikationsdatum: 29.02.2016
Verlag: Springer US
Erschienen in: Endocrine / Ausgabe 3/2016
Print ISSN: 1355-008X
Elektronische ISSN: 1559-0100
DOI: https://doi.org/10.1007/s12020-016-0882-0

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