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Erschienen in: Neurocritical Care 1/2010

01.08.2010 | Ethical Matters

Aggressive Care After a Massive Stroke in Young Patients: Is That What They Want?

verfasst von: Kazuma Nakagawa, Matt T. Bianchi, Shawn S. Nakagawa, Farzaneh A. Sorond

Erschienen in: Neurocritical Care | Ausgabe 1/2010

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Abstract

Background

The assumption is often made that aggressive care in the form of early decompressive hemicraniectomy is appropriate for young patients who suffer a massive stroke. However, neither their attitude toward aggressive treatment, nor their perception of acceptable quality of life after a stroke, has been adequately studied.

Methods

We conducted a cross-sectional questionnaire-based survey that consisted of demographic information and attitude toward neurological disability based on the highest acceptable modified Rankin Scale (mRS) that they would be “willing to live with.” Young adults in the Los Angeles County were surveyed and grouped by whether or not they would want early decompressive hemicraniectomy after a massive stroke. Logistic regression analysis was used to determine the factors associated with willingness to accept decompressive hemicraniectomy.

Results

Sixty-eight community-dwelling young adults (mean age: 24 ± 6 years) were surveyed. The highest acceptable mRS (0–5) participants felt “willing to live with” were: 10.3% (0), 29.4% (1), 27.9% (2), 20.6% (3), 8.8% (4), 2.9% (5). Despite being presented with a hypothetical high likelihood of long-term disability, 46 of 68 (68%) reported they would undergo hemicraniectomy. Neither the demographic factors nor the highest acceptable mRS was associated with the willingness to seek decompressive hemicraniectomy.

Conclusion

Our study supports the commonly held assumption that the majority of young adults would favor early decompressive hemicraniectomy after a massive ischemic stroke. We also show that a substantial minority in this age group is reluctant to accept this aggressive measure, emphasizing the importance of discussing the individual’s previously stated wishes, even in the young population.
Literatur
1.
Zurück zum Zitat Varona JF, Guerra JM, Bermejo F. Stroke in young adults. Med Clin (Barc). 2004;122:70–4. Varona JF, Guerra JM, Bermejo F. Stroke in young adults. Med Clin (Barc). 2004;122:70–4.
2.
Zurück zum Zitat Rasura M, Spalloni A, Ferrari M, et al. A case series of young stroke in Rome. Eur J Neurol. 2006;13:146–52.CrossRefPubMed Rasura M, Spalloni A, Ferrari M, et al. A case series of young stroke in Rome. Eur J Neurol. 2006;13:146–52.CrossRefPubMed
3.
Zurück zum Zitat Kwon SU, Kim JS, Lee JH, Lee MC. Ischemic stroke in Korean young adults. Acta Neurol Scand. 2000;101:19–24.CrossRefPubMed Kwon SU, Kim JS, Lee JH, Lee MC. Ischemic stroke in Korean young adults. Acta Neurol Scand. 2000;101:19–24.CrossRefPubMed
4.
Zurück zum Zitat Alvarez J, Matias-Guiu J, Sumalla J, et al. Ischemic stroke in young adults. I. Analysis of the etiological subgroups. Acta Neurol Scand. 1989;80:28–34.CrossRefPubMed Alvarez J, Matias-Guiu J, Sumalla J, et al. Ischemic stroke in young adults. I. Analysis of the etiological subgroups. Acta Neurol Scand. 1989;80:28–34.CrossRefPubMed
5.
Zurück zum Zitat Sloan MA, Kittner SJ, Feeser BR, et al. Illicit drug-associated ischemic stroke in the Baltimore–Washington Young Stroke Study. Neurology. 1998;50:1688–93.PubMed Sloan MA, Kittner SJ, Feeser BR, et al. Illicit drug-associated ischemic stroke in the Baltimore–Washington Young Stroke Study. Neurology. 1998;50:1688–93.PubMed
6.
Zurück zum Zitat Kittner SJ, Stern BJ, Wozniak M, et al. Cerebral infarction in young adults: the Baltimore–Washington Cooperative Young Stroke Study. Neurology. 1998;50:890–4.PubMed Kittner SJ, Stern BJ, Wozniak M, et al. Cerebral infarction in young adults: the Baltimore–Washington Cooperative Young Stroke Study. Neurology. 1998;50:890–4.PubMed
7.
Zurück zum Zitat Kristensen B, Malm J, Carlberg B, et al. Epidemiology and etiology of ischemic stroke in young adults aged 18 to 44 years in northern Sweden. Stroke. 1997;28:1702–9.PubMed Kristensen B, Malm J, Carlberg B, et al. Epidemiology and etiology of ischemic stroke in young adults aged 18 to 44 years in northern Sweden. Stroke. 1997;28:1702–9.PubMed
8.
Zurück zum Zitat Bogousslavsky J, Pierre P. Ischemic stroke in patients under age 45. Neurol Clin. 1992;10:113–24.PubMed Bogousslavsky J, Pierre P. Ischemic stroke in patients under age 45. Neurol Clin. 1992;10:113–24.PubMed
9.
Zurück zum Zitat Adams HP Jr, Kappelle LJ, Biller J, et al. Ischemic stroke in young adults. Experience in 329 patients enrolled in the Iowa Registry of stroke in young adults. Arch Neurol. 1995;52:491–5.PubMed Adams HP Jr, Kappelle LJ, Biller J, et al. Ischemic stroke in young adults. Experience in 329 patients enrolled in the Iowa Registry of stroke in young adults. Arch Neurol. 1995;52:491–5.PubMed
10.
Zurück zum Zitat Bogousslavsky J, Regli F. Ischemic stroke in adults younger than 30 years of age. Cause and prognosis. Arch Neurol. 1987;44:479–82.PubMed Bogousslavsky J, Regli F. Ischemic stroke in adults younger than 30 years of age. Cause and prognosis. Arch Neurol. 1987;44:479–82.PubMed
11.
Zurück zum Zitat Varona JF, Guerra JM, Bermejo F, Molina JA, Gomez de la Camara A. Causes of ischemic stroke in young adults, and evolution of the etiological diagnosis over the long term. Eur Neurol. 2007;57:212–8.CrossRefPubMed Varona JF, Guerra JM, Bermejo F, Molina JA, Gomez de la Camara A. Causes of ischemic stroke in young adults, and evolution of the etiological diagnosis over the long term. Eur Neurol. 2007;57:212–8.CrossRefPubMed
12.
Zurück zum Zitat Nencini P, Inzitari D, Baruffi MC, et al. Incidence of stroke in young adults in Florence, Italy. Stroke. 1988;19:977–81.PubMed Nencini P, Inzitari D, Baruffi MC, et al. Incidence of stroke in young adults in Florence, Italy. Stroke. 1988;19:977–81.PubMed
13.
Zurück zum Zitat Marini C, Totaro R, De Santis F, Ciancarelli I, Baldassarre M, Carolei A. Stroke in young adults in the community-based L’Aquila registry: incidence and prognosis. Stroke. 2001;32:52–6.PubMed Marini C, Totaro R, De Santis F, Ciancarelli I, Baldassarre M, Carolei A. Stroke in young adults in the community-based L’Aquila registry: incidence and prognosis. Stroke. 2001;32:52–6.PubMed
14.
Zurück zum Zitat Putaala J, Curtze S, Hiltunen S, Tolppanen H, Kaste M, Tatlisumak T. Causes of death and predictors of 5-year mortality in young adults after first-ever ischemic stroke: the Helsinki Young Stroke Registry. Stroke. 2009;40:2698–703.CrossRefPubMed Putaala J, Curtze S, Hiltunen S, Tolppanen H, Kaste M, Tatlisumak T. Causes of death and predictors of 5-year mortality in young adults after first-ever ischemic stroke: the Helsinki Young Stroke Registry. Stroke. 2009;40:2698–703.CrossRefPubMed
15.
Zurück zum Zitat Varona JF, Bermejo F, Guerra JM, Molina JA. Long-term prognosis of ischemic stroke in young adults. Study of 272 cases. J Neurol. 2004;251:1507–14.CrossRefPubMed Varona JF, Bermejo F, Guerra JM, Molina JA. Long-term prognosis of ischemic stroke in young adults. Study of 272 cases. J Neurol. 2004;251:1507–14.CrossRefPubMed
16.
Zurück zum Zitat Kappelle LJ, Adams HP Jr, Heffner ML, Torner JC, Gomez F, Biller J. Prognosis of young adults with ischemic stroke. A long-term follow-up study assessing recurrent vascular events and functional outcome in the Iowa Registry of Stroke in Young Adults. Stroke. 1994;25:1360–5.PubMed Kappelle LJ, Adams HP Jr, Heffner ML, Torner JC, Gomez F, Biller J. Prognosis of young adults with ischemic stroke. A long-term follow-up study assessing recurrent vascular events and functional outcome in the Iowa Registry of Stroke in Young Adults. Stroke. 1994;25:1360–5.PubMed
17.
Zurück zum Zitat Naess H, Waje-Andreassen U, Thomassen L, Nyland H, Myhr KM. Health-related quality of life among young adults with ischemic stroke on long-term follow-up. Stroke. 2006;37:1232–6.CrossRefPubMed Naess H, Waje-Andreassen U, Thomassen L, Nyland H, Myhr KM. Health-related quality of life among young adults with ischemic stroke on long-term follow-up. Stroke. 2006;37:1232–6.CrossRefPubMed
18.
Zurück zum Zitat Neau JP, Ingrand P, Mouille-Brachet C, et al. Functional recovery and social outcome after cerebral infarction in young adults. Cerebrovasc Dis. 1998;8:296–302.CrossRefPubMed Neau JP, Ingrand P, Mouille-Brachet C, et al. Functional recovery and social outcome after cerebral infarction in young adults. Cerebrovasc Dis. 1998;8:296–302.CrossRefPubMed
19.
Zurück zum Zitat Hacke W, Schwab S, Horn M, Spranger M, De Georgia M, von Kummer R. ‘Malignant’ middle cerebral artery territory infarction: clinical course and prognostic signs. Arch Neurol. 1996;53:309–15.PubMed Hacke W, Schwab S, Horn M, Spranger M, De Georgia M, von Kummer R. ‘Malignant’ middle cerebral artery territory infarction: clinical course and prognostic signs. Arch Neurol. 1996;53:309–15.PubMed
20.
Zurück zum Zitat Berrouschot J, Sterker M, Bettin S, Koster J, Schneider D. Mortality of space-occupying (‘malignant’) middle cerebral artery infarction under conservative intensive care. Intensive Care Med. 1998;24:620–3.CrossRefPubMed Berrouschot J, Sterker M, Bettin S, Koster J, Schneider D. Mortality of space-occupying (‘malignant’) middle cerebral artery infarction under conservative intensive care. Intensive Care Med. 1998;24:620–3.CrossRefPubMed
21.
Zurück zum Zitat Vahedi K, Hofmeijer J, Juettler E, et al. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol. 2007;6:215–22.CrossRefPubMed Vahedi K, Hofmeijer J, Juettler E, et al. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol. 2007;6:215–22.CrossRefPubMed
22.
Zurück zum Zitat Gupta R, Connolly ES, Mayer S, Elkind MS. Hemicraniectomy for massive middle cerebral artery territory infarction: a systematic review. Stroke. 2004;35:539–43.CrossRefPubMed Gupta R, Connolly ES, Mayer S, Elkind MS. Hemicraniectomy for massive middle cerebral artery territory infarction: a systematic review. Stroke. 2004;35:539–43.CrossRefPubMed
23.
Zurück zum Zitat Gerhart KA, Koziol-McLain J, Lowenstein SR, Whiteneck GG. Quality of life following spinal cord injury: knowledge and attitudes of emergency care providers. Ann Emerg Med. 1994;23:807–12.CrossRefPubMed Gerhart KA, Koziol-McLain J, Lowenstein SR, Whiteneck GG. Quality of life following spinal cord injury: knowledge and attitudes of emergency care providers. Ann Emerg Med. 1994;23:807–12.CrossRefPubMed
Metadaten
Titel
Aggressive Care After a Massive Stroke in Young Patients: Is That What They Want?
verfasst von
Kazuma Nakagawa
Matt T. Bianchi
Shawn S. Nakagawa
Farzaneh A. Sorond
Publikationsdatum
01.08.2010
Verlag
Humana Press Inc
Erschienen in
Neurocritical Care / Ausgabe 1/2010
Print ISSN: 1541-6933
Elektronische ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-010-9340-7

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