Erschienen in:
01.06.2013 | Women and Heart Disease (J Robinson, Section Editor)
Women and Heart Failure: An Emerging Venus-Mars Concept
Erschienen in:
Current Cardiovascular Risk Reports
|
Ausgabe 3/2013
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Abstract
Some of the most profound sex differences in cardiovascular disease are evident in the syndrome of heart failure. Certain heart failure conditions have a unique predilection for women, such as heart failure with preserved ejection fraction and apical ballooning syndrome; or are exclusive to women, such as peripartum cardiomyopathy. Overall, there are notable differences between women and men in terms heart failure disease burden, risk factors, clinical presentation and prognosis. Yet, women remain under-represented in heart failure clinical trials. Important knowledge gaps exist in our understanding of the pathophysiologic basis for these sex differences and potential for effective sex-specific management strategies.