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Current Reviews in Musculoskeletal Medicine
Erschienen in: Current Reviews in Musculoskeletal Medicine 4/2018

23.10.2018 | Protein-Rich Plasma: From Bench to Treatment of Arthritis (S Choate and J Tokish, Section Editors)

Current Clinical Recommendations for Use of Platelet-Rich Plasma

verfasst von: Adrian D. K. Le, Lawrence Enweze, Malcolm R. DeBaun, Jason L. Dragoo

Erschienen in: Current Reviews in Musculoskeletal Medicine | Ausgabe 4/2018

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Abstract

Purpose of Review

This review evaluates current clinical literature on the use of platelet-rich plasma (PRP), including leukocyte-rich PRP (LR-PRP) and leukocyte-poor PRP (LP-PRP), in order to develop evidence-based recommendations for various musculoskeletal indications.

Recent Findings

Abundant high-quality evidence supports the use of LR-PRP injection for lateral epicondylitis and LP-PRP for osteoarthritis of the knee. Moderate high-quality evidence supports the use of LR-PRP injection for patellar tendinopathy and of PRP injection for plantar fasciitis and donor site pain in patellar tendon graft BTB ACL reconstruction. There is insufficient evidence to routinely recommend PRP for rotator cuff tendinopathy, osteoarthritis of the hip, or high ankle sprains. Current evidence demonstrates a lack of efficacy of PRP for Achilles tendinopathy, muscle injuries, acute fracture or nonunion, surgical augmentation in rotator cuff repair, Achilles tendon repair, and ACL reconstruction.

Summary

PRP is a promising treatment for some musculoskeletal diseases; however, evidence of its efficacy has been highly variable depending on the specific indication. Additional high-quality clinical trials with longer follow-up will be critical in shaping our perspective of this treatment option.
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Metadaten
Titel
Current Clinical Recommendations for Use of Platelet-Rich Plasma
verfasst von
Adrian D. K. Le
Lawrence Enweze
Malcolm R. DeBaun
Jason L. Dragoo
Publikationsdatum
23.10.2018
Verlag
Springer US
Erschienen in
Current Reviews in Musculoskeletal Medicine / Ausgabe 4/2018
Elektronische ISSN: 1935-9748
DOI
https://doi.org/10.1007/s12178-018-9527-7

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