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Erschienen in: Journal of Cardiovascular Translational Research 2/2014

01.03.2014

Acute Mechanical Circulatory Support for Fulminant Myocarditis Complicated by Cardiogenic Shock

verfasst von: Kanika P. Mody, Hiroo Takayama, Elissa Landes, Melana Yuzefpolskaya, Paolo C. Colombo, Yoshifumi Naka, Ulrich P. Jorde, Nir Uriel

Erschienen in: Journal of Cardiovascular Translational Research | Ausgabe 2/2014

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Abstract

In fulminant myocarditis complicated by cardiogenic shock, early mechanical circulatory support (MCS) may prevent cardiomyopathy and death. We sought to examine the outcomes of patients with fulminant myocarditis supported with MCS. A retrospective review of patients with acute cardiogenic shock treated with MCS from 2007 to 2013 was conducted, and patients with a diagnosis of fulminant myocarditis were included in this series. At our center, 260 patients received MCS for acute cardiogenic shock, and 11 were implanted for fulminant myocarditis. Eight received the Centrimag biventricular assist device (BIVAD), and three received veno-arterial extracorporeal membrane oxygenator (VA ECMO), though 1 VA ECMO-supported patient was transitioned to BIVAD due to refractory shock. The mean acute support time was 14.7 ± 4.4 days. Two patients required long-term left ventricular assist devices and were further supported for 55 and 112 days. Eight patients recovered with a mean ejection fraction of 54 ± 7 %, and one was successfully transplanted. Eight patients survived to discharge (73 %) with mean follow-up: 292.6 ± 306.8 days. All three deaths were due to neurologic complications. MCS should be considered in patients with fulminant myocarditis complicated by shock. With aggressive medical therapy, early utilization of MCS carries promising outcomes.
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Metadaten
Titel
Acute Mechanical Circulatory Support for Fulminant Myocarditis Complicated by Cardiogenic Shock
verfasst von
Kanika P. Mody
Hiroo Takayama
Elissa Landes
Melana Yuzefpolskaya
Paolo C. Colombo
Yoshifumi Naka
Ulrich P. Jorde
Nir Uriel
Publikationsdatum
01.03.2014
Verlag
Springer US
Erschienen in
Journal of Cardiovascular Translational Research / Ausgabe 2/2014
Print ISSN: 1937-5387
Elektronische ISSN: 1937-5395
DOI
https://doi.org/10.1007/s12265-013-9521-9

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