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The Cerebellum
Erschienen in: The Cerebellum 1/2011

01.03.2011

Exposure to an Enriched Environment Accelerates Recovery from Cerebellar Lesion

verfasst von: Francesca Foti, Daniela Laricchiuta, Debora Cutuli, Paola De Bartolo, Francesca Gelfo, Francesco Angelucci, Laura Petrosini

Erschienen in: The Cerebellum | Ausgabe 1/2011

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Abstract

The exposure to enriched environments allows the maintenance of normal cognitive functioning even in the presence of brain pathology. Up until now, clinical and experimental studies have investigated environmental effects mainly on the symptoms linked to the presence of neuro-degenerative diseases, and no study has yet analyzed whether prolonged exposure to complex environments allows modifying the clinical expression and compensation of deficits of cerebellar origin. In animals previously exposed to complex stimulations, the effects of cerebellar lesions have been analyzed to verify whether a prolonged and intense exposure to complex stimulations affected the compensation of motor and cognitive functions following a cerebellar lesion. Hemicerebellectomized or intact animals housed in enriched or standard conditions were administered spatial tests. Postural asymmetries and motor behavior were also assessed. Exposure to the enriched environment almost completely compensated the effects of the hemicerebellectomy. In fact, the motor and cognitive performances of the enriched hemicerebellectomized animals were similar to those of the intact animals. The plastic changes induced by enhanced mental and physical activity seem to provide the development of compensatory responses against the disrupting motor and cognitive consequences of the cerebellar damage.
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Metadaten
Titel
Exposure to an Enriched Environment Accelerates Recovery from Cerebellar Lesion
verfasst von
Francesca Foti
Daniela Laricchiuta
Debora Cutuli
Paola De Bartolo
Francesca Gelfo
Francesco Angelucci
Laura Petrosini
Publikationsdatum
01.03.2011
Verlag
Springer-Verlag
Erschienen in
The Cerebellum / Ausgabe 1/2011
Print ISSN: 1473-4222
Elektronische ISSN: 1473-4230
DOI
https://doi.org/10.1007/s12311-010-0236-z

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