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Erschienen in: Neurotherapeutics 1/2019

01.01.2019 | Review

Tractography for Surgical Neuro-Oncology Planning: Towards a Gold Standard

verfasst von: Sandip S. Panesar, Kumar Abhinav, Fang-Cheng Yeh, Timothée Jacquesson, Malie Collins, Juan Fernandez-Miranda

Erschienen in: Neurotherapeutics | Ausgabe 1/2019

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Abstract

Magnetic resonance imaging tractography permits in vivo visualization of white matter structures. Aside from its academic value, tractography has been proven particularly useful to neurosurgeons for preoperative planning. Preoperative tractography permits both qualitative and quantitative analyses of tumor effects upon surrounding white matter, allowing the surgeon to specifically tailor their operative approach. Despite its benefits, there is controversy pertaining to methodology, implementation, and interpretation of results in this context. High-definition fiber tractography (HDFT) is one of several non-tensor tractography approaches permitting visualization of crossing white matter trajectories at high resolutions, dispensing with the well-known shortcomings of diffusion tensor imaging (DTI) tractography. In this article, we provide an overview of the advantages of HDFT in a neurosurgical context, derived from our considerable experience implementing the technique for academic and clinical purposes. We highlight nuances of qualitative and quantitative approaches to using HDFT for brain tumor surgery planning, and integration of tractography with complementary operative adjuncts, and consider areas requiring further research.
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Metadaten
Titel
Tractography for Surgical Neuro-Oncology Planning: Towards a Gold Standard
verfasst von
Sandip S. Panesar
Kumar Abhinav
Fang-Cheng Yeh
Timothée Jacquesson
Malie Collins
Juan Fernandez-Miranda
Publikationsdatum
01.01.2019
Verlag
Springer International Publishing
Erschienen in
Neurotherapeutics / Ausgabe 1/2019
Print ISSN: 1933-7213
Elektronische ISSN: 1878-7479
DOI
https://doi.org/10.1007/s13311-018-00697-x

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