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01.02.2014 | R&D Insight Report

Sofosbuvir: First Global Approval

verfasst von: Gillian M. Keating, Asha Vaidya

Erschienen in: Drugs | Ausgabe 2/2014

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Abstract

Sofosbuvir (Solvadi™), a nucleotide analogue hepatitis C virus NS5B polymerase inhibitor, is under development with Gilead Sciences for the once-daily, oral treatment of chronic hepatitis C. Oral sofosbuvir has been approved in the US for the treatment of chronic hepatitis C as a component of a combination antiviral regimen. In addition, the European Medicines Agency’s Committee for Medicinal Products for Human Use has recommended the approval of sofosbuvir for the treatment of chronic hepatitis C. This article summarizes the milestones in the development of sofosbuvir leading to this first approval for chronic hepatitis C.

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Titel: Sofosbuvir: First Global Approval
verfasst von: Gillian M. Keating
Asha Vaidya
Publikationsdatum: 01.02.2014
Verlag: Springer International Publishing
Erschienen in: Drugs / Ausgabe 2/2014
Print ISSN: 0012-6667
Elektronische ISSN: 1179-1950
DOI: https://doi.org/10.1007/s40265-014-0179-7

Springer Medizin

Abstract

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