Background
Methods
Study design and setting
Data collection and serology
Data management and analysis plan
Ethical issues
Results
Hepatitis B virus | ||||
---|---|---|---|---|
Risk Factor | Positive n (%) | Negative n (%) | Odds Ratio (OR) 95% confidence interval (CI) | P value |
Therapeutic Injections
| ||||
Yes | 45 (69.2) | 1766 (50.9) | ||
No | 20 (30.8) | 1702 (49.1) | 2.2 (1.3 – 3.6) | 0.003 |
Use of new needle & and syringe
| ||||
Yes | 44 (67.7) | 1694 (48.8) | ||
No | 21 (32.3) | 1774 (51.2) | 2.2 (1.3 – 3.7) | 0.003 |
No: of Injections in the last year
| ||||
<2 injections | 4 (12.5) | 371 (28.2) | Reference | |
2–5 injections | 13 (40.7) | 462 (35.2) | 2.6 (0.8 – 8.1) | |
>5 injections | 15 (46.8) | 481 (36.6) | 2.9 (1.0 – 852) | 0.140 |
Received Blood Transfusion
| ||||
Yes | 1 (1.5) | 51 (1.5) | ||
No | 64 (98.5) | 3417 (98.5) | 1.0 (0.1 – 7.7) | 0.964 |
Hospitalized
| ||||
Yes | 16 (24.6) | 590 (17) | ||
No | 49 (75.4) | 2878(83) | 1.6 (0.9 – 12.8) | 0.107 |
Family member died of Liver disease
| ||||
Yes | 7(10.8) | 361 (10.4) | ||
No | 58 (89.2) | 3107 (89.6) | 1.0 (0.5 – 2.3) | 0.925 |
Diagnosis in Family member
| ||||
HCV | 1 (14.3) | 12 (3.2) | ||
HBV | 1 (14.3) | 36 (10) | - | |
Jaundice | 5 (71.4) | 306 (84.8) | ||
Liver disease | 0 | 7 (2) | 0.433 | |
Sharing of various items with infected person
| ||||
Yes | 4 (57.1) | 110 (31) | ||
No | 3 (42.9) | 244 (69) | 3.0 (0.7 – 13.4) | 0.147 |
Previous Immunization
| ||||
Vaccinated | 54 (83) | 3001(86.5) | ||
Non-Vaccinated | 11 (7) | 467 (13.5) | 1.3 (0.7 – 2.5) | 0.419 |
Place vaccinated
| ||||
Private Sector | 7 (10.8) | 1030 (29.7) | Reference | |
Govt. Sector | 46 (70.7) | 1974 (57) | 3.4 (1.5 – 7.6) | |
None | 12 (18.5) | 464 (13.3) | 3.8 (1.5 – 9.7) | 0.022 |
Visit to Barber Shop
| ||||
Yes | 47 (72.3) | 2814 (81.1) | ||
No | 18 (27.7) | 654 (18.9) | 0.6 (0.4 – 1.1) | 0.072 |
Received cuts at Barber Shop
| ||||
Yes | 11 (23.4) | 686 (24.4) | ||
No | 36 (76.6) | 2128 (75.6) | 0.9 (0.5 – 1.9) | 0.877 |
Child's ear/nose pierced
| ||||
Yes | 22 (33.8) | 1293 (37.3) | ||
No | 43 (66.2) | 2175 (62.7) | 0.9 (0.5 – 1.4) | 0.570 |
Dental treatment
| ||||
Yes | 0 | 107 (3) | ||
No | 65 (100) | 3361 (97) | - | 0.150 |
Father education status
| ||||
Educated | 34 (52.3) | 2300 (66.3) | ||
Non-Educated | 31 (47.7) | 1168 (33.7) | 1.8 (1.1 – 2.9) | 0.018 |
Mother education status
| ||||
Educated | 25 (38.5) | 1964 (56.6) | ||
Non-Educated | 40 (61.5) | 1504 (43.4) | 2.1 (1.3 – 3.5) | 0.003 |
Ethnic Origin
| ||||
Sindhi | 1 (1.5) | 86 (2.5) | Reference | |
Balochi | 12 (18.5) | 133 (3.9) | 7.8 (1.0 – 60.8) | |
Punjabi | 10 (15.4) | 996 (28.8) | 0.9 (0.1 – 6.8) | < 0.001 |
Pathan | 4 (6.2) | 179 (5) | 1.9 (0.2 – 17.5) | |
Mohajirs | 19 (29.2) | 1796 (51.8) | 0.9 (0.1 – 6.9) | |
Others | 19 (29.2) | 278 (8) | 5.3 (0.7 – 40.1) | |
Age Group (years)
| ||||
≤ 5 years | 17 (26.2) | 915 (26.4) | Reference | |
6 – 9 years | 14 (21.5) | 931 (26.8) | 0.8 (0.4 – 1.7) | |
10 – 13 years | 16 (24.6) | 934 (27) | 0.9 (0.5 – 1.8) | |
> 13 years | 18 (27.7) | 688 (19.8) | 1.4 (0.7 – 2.8) | 0.428 |
Gender
| ||||
Boys | 38 (58.5) | 1788 (51.6) | ||
Girls | 27 (41.5) | 1680 (48.4) | 1.3 (0.8 – 2.2) | 0.270 |
Anti-Hepatitis C antibody | ||||
---|---|---|---|---|
Risk Factor | Positive n (%) | Negative n (%) | Odds Ratio (OR) 95% confidence interval (CI) | P value |
Therapeutic Injections
| ||||
Yes | 28 (50.9) | 1783 (51.3) | ||
No | 27 (49.1) | 1695 (48.7) | 0.9 (0.6 – 1.6) | 0.958 |
Use of new needle & and syringe
| ||||
Yes | 28 (50.9) | 1710 (49.2) | ||
No | 27 (49.1) | 1768 (50.8) | 1.0 (0.6 – 1.8) | 0.798 |
No: of Injections in the last year
| ||||
<2 injections | 7(38.9) | 368 (27.7) | Reference | |
2–5 injections | 4 (22.2) | 471 (35.5) | 0.4 (0.1 – 1.5) | |
>5 injections | 7 (38.9) | 489 (36.8) | 0.8 (0.3 – 2.2) | 0.427 |
Received Blood Transfusion
| ||||
Yes | 2 (3.7) | 50 (1.4) | ||
No | 53 (96.3) | 3428 (98.6) | 2.6 (0.6 – 10.9) | 0.179 |
Hospitalized
| ||||
Yes | 12 (21.8) | 594 (17) | ||
No | 43 (78.2) | 2884(83) | 1.4 (0.7 – 2.6) | 0.355 |
Family member died of Liver disease
| ||||
Yes | 8(14.5) | 360 (10.3) | ||
No | 47 (85.5) | 3118 (89.7) | 1.5 (0.7 – 3.1) | 0.312 |
Diagnosis in Family member
| ||||
HCV | 1 (12.5) | 12 (3.4) | ||
HBV | 0 | 37 (10.5) | - | |
Jaundice | 7(87.5) | 304 (86.1) | 0.380 | |
Previous Immunization
| ||||
Vaccinated | 47 (85.5) | 3008 (86.5) | ||
Non-Vaccinated | 8 (14.5) | 470 (13.5) | 0.9 (0.4 – 2.0) | 0.842 |
Place vaccinated
| ||||
Private Sector | 14 (25.5) | 1023 (29.4) | Reference | |
Govt. Sector | 33 (60) | 1987 (57.1) | 1.2 (0.6 – 2.3) | |
None | 8 (14.5) | 469(13.5) | 1.2 (0.5 – 3.0) | 0.930 |
Visit to Barber Shop
| ||||
Yes | 45 (81.8) | 2816 (81) | ||
No | 10 (18.2) | 662 (19) | 1.1 (0.5 – 2.1) | 0.873 |
Received cuts at Barber Shop
| ||||
Yes | 7 (15.6) | 690 (24.5) | ||
No | 38 (84.4) | 2126 (75.5) | 0.6 (0.3 – 1.3) | 0.165 |
Child's ear/nose pierced
| ||||
Yes | 19 (34.6) | 1296 (37.2) | ||
No | 36 (65.4) | 2182 (62.8) | 0.9 (0.5 – 1.6) | 0.679 |
Dental treatment
| ||||
Yes | 1 (1.9) | 106 (3) | ||
No | 54 (98.1) | 3372 (97) | 0.6 (0.1 – 4.3) | 0.598 |
Father education status
| ||||
Educated | 36 (65.5) | 2298 (66) | ||
Non-Educated | 19 (34.5) | 1180 (34) | 1.0 (0.6 – 1.8) | 0.924 |
Mother education status
| ||||
Educated | 24 (43.7) | 1965 (56.5) | ||
Non-Educated | 31 (56.3) | 1513 (43.5) | 1.7 (0.9 – 2.9) | 0.056 |
Ethnic Origin
| ||||
Sindhi | 1 (1.8) | 86 (2.5) | Reference | |
Balochi | 3 (5.5) | 142 (4) | 1.8 (0.2 – 17.7) | |
Punjabi | 16 (29) | 990 (28.5) | 1.4 (0.2 – 10.6) | |
Pathan | 4 (7.3) | 179 (5.1) | 1.9 (0.2 – 17.5) | 0.568 |
Muhajirs | 23 (41.8) | 1792 (51.5) | 1.1 (0.1 – 8.3) | |
Others | 8 (14.6) | 289 (8.4) | 2.4 (0.3 – 19.3) | |
Age Group (years)
| ||||
<= 5 | 13 (23.5) | 919 (26.4) | Reference | |
6–9 | 14 (25.5) | 931 (26.8) | 1.1 (0.5 – 2.3) | |
10–13 | 14 (25.5) | 936 (27) | 1.1 (0.5 – 2.3) | |
> 13 | 14 (25.5) | 692 (19.8) | 1.4 (0.7 – 3.1) | 0.783 |
Gender
| ||||
Boys | 32 (58.2) | 1794 (51.6) | ||
Girls | 23 (41.8) | 1684 (48.4) | 0.7 (0.4–1.3) | 0.331 |
Demographic features of the study population
Area of study population
Accommodation
Educational status
Risk Factor | Adjusted odds Ratio (AOR) | 95% confidence interval (CI) | P value |
---|---|---|---|
Use of new needle & and syringe | |||
No | Reference | ||
Yes | 1.9 | (1.1 – 3.3) | 0.033 |
Place vaccinated
| |||
Private Sector | Reference | ||
Govt. Sector | 2.4 | (1.1 – 5.2) | 0.030 |
Father education status
| |||
Educated | Reference | ||
Non-Educated | 1.4 | (0.7 – 2.7) | 0.333 |
Mother education status
| |||
Educated | Reference | ||
Non-Educated | 1.4 | (0.6 – 2.7) | 0.361 |