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Clinical Drug Investigation

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01.12.2004 | Short Communication

Cerebral Blood Flow before and after Treatment with Amlodipine in Elderly Patients with Lacunar Infarction

verfasst von: Dr Toshio Imaizumi, Masahiko Chiba, Toshimi Honma, Junpei Yoshikawa, Jun Niwa

Erschienen in: Clinical Drug Investigation | Ausgabe 12/2004

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Because the autoregulation of cerebral blood flow (CBF) is impaired in patients with acute ischaemic stroke, blood pressure (BP) reductions may induce further ischaemia.[1‐3] However, the treatment of hypertension reduces the risk of ischaemic stroke.[4‐10] Moreover, a BP reduction in subacute and chronic stroke may also prevent lipohyalinosis and other vascular lesions associated with stroke. Although some studies have investigated the effect of BP lowering in the acute and subacute phases of stroke,[11‐13] the duration and degree of a BP reduction remains controversial.[4‐7,14,15] …

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Titel: Cerebral Blood Flow before and after Treatment with Amlodipine in Elderly Patients with Lacunar Infarction
verfasst von: Dr Toshio Imaizumi
Masahiko Chiba
Toshimi Honma
Junpei Yoshikawa
Jun Niwa
Publikationsdatum: 01.12.2004
Verlag: Springer International Publishing
Erschienen in: Clinical Drug Investigation / Ausgabe 12/2004
Print ISSN: 1173-2563
Elektronische ISSN: 1179-1918
DOI: https://doi.org/10.2165/00044011-200424120-00009

Springer Medizin

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