Introduction
Characteristics of MAFG-AS1 in human cancers
Disease type | Expression | Clinical characteristics | Refs. |
---|---|---|---|
Breast cancer | Upregulated | Tumor size, and ki-67 | |
Lung cancer | Upregulated | OS | |
Liver cancer | Upregulated | OS | |
Bladder cancer | Upregulated | DFS, OS, clinical stages, and TMN stages | |
Colorectal cancer | Upregulated | Depth of invasion, TNM stage, OS, and DFS | |
Gastric cancer | Upregulated | Clinical stage, depth of invasion, lymph node metastasis, distant metastasis, and OS | |
Esophageal cancer | Upregulated | OS | [69] |
Prostate cancer | Upregulated | – | [70] |
Pancreatic cancer | Upregulated | – | [71] |
Ovarian cancer | Upregulated | Tumor stage, size, lymph node metastasis, and OS | [72] |
Glioma | Upregulated | – | [73] |
Disease type | Cell lines | Functions | Related mechanisms | Refs. |
---|---|---|---|---|
Breast cancer | MCF7, MCF10, SUM149, HCC1937, BT474, Hs578T, SK-BR-3, MDA-MB-468, MDA-MB-231, and T47D | Cell proliferation, invasion, metastasis, apoptosis, and autophagy | miR-3612, FKBP4, miR-574-5p, SOD2, miR-150-5p, MYB, miR-339-5p, CDK2, miR-339-5p, MMP15, miR-3196, TFAP2A, JAK2, STAT3, and STC2 | |
Lung cancer | H1373, H1975, H1650, HCC827, A549, PC-9, and Calu-3 | Cell proliferation, migration, and invasion | miR-339-5p, MMP15, miR-744-5p, MAFG, miR-3196, and SOX12 | |
Liver cancer | Huh7, HepG2, LM3, HCCLM3, Hep3B, and MHCC97-H | Cell proliferation, migration, invasion, and drug resistance | miR-3196, STRN4, E2F1, MAFG, miR-3196, OTX1, and miR-6852 | |
Bladder cancer | HT01197, 5637, BIU87, EJ, RT4, J82, T24, HT-1376, UMUC3, and SVHUC1 | Cell proliferation, migration, and invasion | miR-125b-5p, SphK1, HuR, PTBP1, miR-143-3p, COX-2, miR-143-3p, and SERPINE1 | |
Colorectal cancer | HCT116, HT29, SW1116, SW480, and LoVo | Cell migration, proliferation, invasion, and glycolysis | miR-147b, NDUFA4, miRNA-149-3p, and HOXB8 | |
Gastric cancer | MKN-45, AGS, and SGC7901 | Cell proliferation, migration, and invasion | miR-505, and PLK1 | |
Esophageal cancer | EC9706, EC109, KYSE30, and KYSE150 | Cell proliferation, migration, invasion, and aerobic glycolysis | miR-765, and PDX1 | [69] |
Prostate cancer | DU145, and PC-3 | Cell proliferation and invasion | miR-3196, and NFIX | [70] |
Pancreatic cancer | Capan 1, CFPAC-1, SW1990, and PANC-1 | Cell proliferation and migration | NFKB1, and IGF1 | [71] |
Ovarian cancer | A2780, Caov-3, RMG-I, Caov-4, and CoC1 | Cell invasion and migration | – | [72] |
Glioma | U87, and U-118 | Cell proliferation | miR-34a | [73] |